Lipid

Crucial building blocks of life on Earth can more easily form in outer space – new research

Retrieved on: 
Thursday, April 18, 2024

Scientists believe life arose in a primordial soup of organic chemicals and biomolecules on the early Earth, eventually leading to actual organisms.

Key Points: 
  • Scientists believe life arose in a primordial soup of organic chemicals and biomolecules on the early Earth, eventually leading to actual organisms.
  • However, these complex molecules are assembled from a variety of small and simple molecules such as amino acids – the so-called building blocks of life.
  • This latest study sheds light on how some of these building blocks might have formed and assembled, and how they ended up on Earth.

Steps to life

  • Peptides can be made up of as little as two amino acids, but also range to hundreds of amino acids.
  • The assemblage of amino acids into peptides is an important step because peptides provide functions such as “catalysing”, or enhancing, reactions that are important to maintaining life.
  • However, despite their potentially important role in the origin of life, it was not so straightforward for peptides to form spontaneously under the environmental conditions on the early Earth.
  • Many of the building blocks of life such as amino acids, lipids and sugars can form in the space environment.
  • Because peptide formation is more efficient in space than on Earth, and because they can accumulate in comets, their impacts on the early Earth might have delivered loads that boosted the steps towards the origin of life on Earth.
  • So what does all this mean for our chances of finding alien life?
  • Once we know that, we’ll have a good idea of how widespread, or not, life might be.


Christian Schroeder does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Drinking apple cider vinegar may help with weight loss but its health benefits are overstated

Retrieved on: 
Wednesday, April 10, 2024

One day, she explained that she adds apple cider vinegar to improve my health.

Key Points: 
  • One day, she explained that she adds apple cider vinegar to improve my health.
  • Apple cider vinegar is a natural product made of fermented apple juice that has gone sour.
  • I decided to turn medical sleuth and investigate whether apple cider vinegar is as good for health as it sounds.

Claim: disinfectant properties

  • But does apple cider vinegar’s decontaminant qualities translate to the human gut?
  • Our stomachs produce acid, which acts as a natural barrier to infection, so how can adding more acid help?

Claim: weight loss and management of type 2 diabetes

  • There are plenty of anecdotal claims that apple cider vinegar can aid weight loss, supported by limited evidence from several small studies.
  • Apple cider vinegar is thought to cause weight loss through its effect on delay of gastric emptying.
  • Reduced calorific intake will lead to weight loss – but how are the metabolic effects on blood glucose and lipids mediated?
  • In type 2 diabetes there is a reduction in sensitivity to insulin which in turn leads to a reduced uptake of glucose by cells.

Claim: reduces risk of heart disease

  • Raised blood lipids are a risk factor for cardiovascular diseases such as myocardial infarction and stroke.
  • Well, I’m afraid there’s no scientific evidence that vinegar consumption of any kind reduces cardiovascular morbidity and mortality in those with or without diabetes.

Claim: cancer treatment and prevention

  • One of the more outrageous claims of benefits of daily apple cider vinegar consumption is that it may prevent or treat cancer.
  • A frequently quoted case-control study from China found that an increased consumption of vinegar was associated with a reduced incidence of oesophageal cancer.


Stephen Hughes does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

NuCana Presents Data at the AACR 2024 Annual Meeting Highlighting the Ability of NUC-7738 to Profoundly Alter Tumor Biology in a Paired Biopsy Clinical Study

Retrieved on: 
Tuesday, April 9, 2024

SAN DIEGO, April 09, 2024 (GLOBE NEWSWIRE) -- NuCana plc (NASDAQ: NCNA) announced two posters being presented today at the American Association of Cancer Research (AACR) Annual Meeting.

Key Points: 
  • The tumor microenvironment (TME) is a complex interplay of various cell types, extracellular matrix, signalling molecules and physical factors that collectively influence tumor growth.
  • Lipids play an important role in the TME, contributing to various aspects of cancer progression and therapy resistance.
  • They also further explain the compelling clinical data we have generated with NUC-7738 as a monotherapy and in combination with pembrolizumab.
  • Our translational data help us to understand these clinical observations and guide the optimal development pathway for NUC-7738.

Altimmune Announces Positive Lean Mass Preservation Data for Pemvidutide and Reports Fourth Quarter and Full Year 2023 Financial Results

Retrieved on: 
Wednesday, March 27, 2024

“We are extremely pleased with the results of the body composition analysis from our recently completed MOMENTUM 48-week Phase 2 obesity trial of pemvidutide.

Key Points: 
  • “We are extremely pleased with the results of the body composition analysis from our recently completed MOMENTUM 48-week Phase 2 obesity trial of pemvidutide.
  • “There is a growing appreciation that the quality of weight loss is as important as the quantity of weight loss.
  • Achieved mean weight loss of 15.6% on 2.4 mg dose of pemvidutide at week 48, with weight loss continuing at the end of treatment.
  • Financial Results for the Three Months Ended December 31, 2023
    Altimmune had cash, cash equivalents and short-term investments totaling $198.0 million at December 31, 2023.

ZyVersa Therapeutics Announces IRB Approval of Phase 2a Clinical Trial Protocol to Evaluate Cholesterol Efflux Mediator™ VAR 200 in Patients with Diabetic Kidney Disease

Retrieved on: 
Monday, March 18, 2024

Cholesterol Efflux MediatorTM VAR 200 is in development to ameliorate renal lipid accumulation that damages the kidneys’ filtration system, leading to chronic kidney disease and its progression.

Key Points: 
  • Cholesterol Efflux MediatorTM VAR 200 is in development to ameliorate renal lipid accumulation that damages the kidneys’ filtration system, leading to chronic kidney disease and its progression.
  • WESTON, Fla., March 18, 2024 (GLOBE NEWSWIRE) -- ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA, or “ZyVersa”), a clinical stage specialty biopharmaceutical company developing first-in-class drugs for the treatment of renal and inflammatory diseases with high unmet medical needs, announces Institutional Review Board (IRB) approval of the Phase 2a clinical trial protocol to evaluate the efficacy and safety of Cholesterol Efflux Mediator VAR 200 in patients with diabetic kidney disease.
  • It is the first in human trial for VAR 200 intended to substantiate that the promising preclinical results demonstrated in three different animal models of kidney disease (diabetic kidney disease, focal segmental glomerulosclerosis, and Alport syndrome) translate to patients with kidney disease.
  • We are excited about the potential of Cholesterol Efflux MediatorTM VAR 200 to protect against kidney injury and reduce kidney disease progression.”

Global Algae Biofuel Industry Research 2024: Government Policies Expected to Create Opportunities - Analysis and Forecasts to 2033 - ResearchAndMarkets.com

Retrieved on: 
Wednesday, April 3, 2024

The global shift toward sustainability is a key driver in the global algae biofuel market, driving both innovation and investment in this renewable energy sector.

Key Points: 
  • The global shift toward sustainability is a key driver in the global algae biofuel market, driving both innovation and investment in this renewable energy sector.
  • These policies enhance the market viability of algae biofuels by providing financial incentives, tax breaks, and research grants.
  • North America led the global algae biofuel market in 2022, owing to several key factors that propelled the region to the forefront of this burgeoning industry.
  • Government initiatives and supportive policies, such as research funding and tax incentives, have fostered a conducive environment for algae biofuel development.

Lipids with potential health benefits in herbal teas

Retrieved on: 
Wednesday, April 3, 2024

SAPPORO, Japan, April 3, 2024 /PRNewswire/ -- Herbal teas are enjoyed worldwide, not only for their taste and refreshment but also for a wide range of reputed health benefits. But the potential significance of a category of compounds called lipids in the teas has been relatively unexplored. Researchers at Hokkaido University, led by Associate Professor Siddabasave Gowda and Professor Shu-Ping Hui of the Faculty of Health Sciences, have now identified 341 different molecular species from five categories of lipids in samples of four types of herbal tea. They published their results in the journal Food Chemistry.

Key Points: 
  • Hokkaido University researchers have identified new lipids in some herbal teas in detail for the first time, preparing the ground for investigating their contribution to the health benefits of the teas.
  • SAPPORO, Japan, April 3, 2024 /PRNewswire/ -- Herbal teas are enjoyed worldwide, not only for their taste and refreshment but also for a wide range of reputed health benefits.
  • But the potential significance of a category of compounds called lipids in the teas has been relatively unexplored.
  • "Our initial study paves the way for further exploration of the role of lipids in herbal teas and their broad implications for human health and nutrition," Gowda concludes.

Lipids with potential health benefits in herbal teas

Retrieved on: 
Wednesday, April 3, 2024

SAPPORO, Japan, April 3, 2024 /PRNewswire/ -- Herbal teas are enjoyed worldwide, not only for their taste and refreshment but also for a wide range of reputed health benefits. But the potential significance of a category of compounds called lipids in the teas has been relatively unexplored. Researchers at Hokkaido University, led by Associate Professor Siddabasave Gowda and Professor Shu-Ping Hui of the Faculty of Health Sciences, have now identified 341 different molecular species from five categories of lipids in samples of four types of herbal tea. They published their results in the journal Food Chemistry.

Key Points: 
  • Hokkaido University researchers have identified new lipids in some herbal teas in detail for the first time, preparing the ground for investigating their contribution to the health benefits of the teas.
  • SAPPORO, Japan, April 3, 2024 /PRNewswire/ -- Herbal teas are enjoyed worldwide, not only for their taste and refreshment but also for a wide range of reputed health benefits.
  • But the potential significance of a category of compounds called lipids in the teas has been relatively unexplored.
  • "Our initial study paves the way for further exploration of the role of lipids in herbal teas and their broad implications for human health and nutrition," Gowda concludes.

Obagi Cosmeceuticals Announces the Launch of Daily Hydro-Drops® Rejuvenating Eye Gel Cream

Retrieved on: 
Thursday, March 7, 2024

LONG BEACH, Calif., March 07, 2024 (GLOBE NEWSWIRE) -- Obagi Cosmeceuticals LLC (“Obagi”), a leader in skincare innovation and the originator of medical-grade skincare and a subsidiary of Waldencast plc, (NASDAQ: WALD) (“Waldencast”), today announced the launch of Daily Hydro-Drops® Rejuvenating Eye Gel Cream.

Key Points: 
  • LONG BEACH, Calif., March 07, 2024 (GLOBE NEWSWIRE) -- Obagi Cosmeceuticals LLC (“Obagi”), a leader in skincare innovation and the originator of medical-grade skincare and a subsidiary of Waldencast plc, (NASDAQ: WALD) (“Waldencast”), today announced the launch of Daily Hydro-Drops® Rejuvenating Eye Gel Cream.
  • Daily Hydro-Drops® Rejuvenating Eye Gel Cream offers a transformative solution to the eye area, bringing an immediate boost in radiance, while simultaneously rejuvenating the eye area with 24-hour lasting hydration for a more awakened appearance.
  • With just one swipe, Rejuvenating Eye Gel Cream delivers brighter, smoother, and more hydrated skin around the eyes.
  • Multimodal efficacy testing was completed to demonstrate the efficacy of Daily Hydro-Drops® Rejuvenating Eye Gel Cream, revealing the below findings after various time increments:
    Daily Hydro-Drops® Rejuvenating Eye Gel Cream is now available for $75 through partnering physician channels, and will be available for customers to purchase on Obagi.com on March 21st.

Capricor Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update

Retrieved on: 
Thursday, February 29, 2024

Further, Capricor will receive a meaningful mid-range double-digit revenue share of product revenue under the terms of this Agreement.

Key Points: 
  • Further, Capricor will receive a meaningful mid-range double-digit revenue share of product revenue under the terms of this Agreement.
  • Next steps for Cohort A: plan to report top-line data in the fourth quarter of 2024.
  • Revenues for the fourth quarter of 2023 were approximately $12.1 million compared with approximately $1.0 million for the fourth quarter of 2022.
  • Operating expenses: Total operating expenses for the fourth quarter of 2023 were approximately $13.2 million compared with approximately $9.0 million for the fourth quarter of 2022.