Eye

IceCube researchers detect a rare type of energetic neutrino sent from powerful astronomical objects

Retrieved on: 
Thursday, April 25, 2024

In fact, only one of them is likely to lightly tap an atom in your body in your entire lifetime.

Key Points: 
  • In fact, only one of them is likely to lightly tap an atom in your body in your entire lifetime.
  • While much rarer, these energetic neutrinos are more likely to crash into something and create a signal that physicists like me can detect.
  • IceCube, one such experiment, documented an especially rare type of particularly energetic astrophysical neutrino in a study published in April 2024.

IceCube observatory

  • The IceCube Neutrino Observatory is the 800-pound gorilla of large neutrino experiments.
  • But the tau neutrino, one type of particularly energetic neutrino, has eluded IceCube – until now.

Neutrino flavors

  • When a neutrino bangs into another particle, it usually produces a charged particle that corresponds with its flavor.
  • A muon neutrino produces a muon, an electron neutrino produces an electron, and a tau neutrino produces a tau.
  • The third flavor of neutrino, the tau neutrino, is the chameleon of the trio.
  • One tau neutrino can appear as a track of light, while the next can appear as a ball.

Energetic tau neutrinos

  • This data confirms IceCube’s earlier discovery of astrophysical neutrinos, and they confirm a hint that IceCube previously picked up of astrophysical tau neutrinos.
  • In particular, the detection of astrophysical tau neutrinos confirms that energetic neutrinos from distant sources change flavor, or oscillate.
  • As IceCube and other neutrino experiments gather more data, and scientists get better at distinguishing the three neutrino flavors, researchers will eventually be able to guess how neutrinos that come from black holes are produced.
  • There will always be fewer energetic tau neutrinos and their muon and electron cousins compared with the more common neutrinos that come from the Big Bang.


Doug Cowen receives funding from the National Science Foundation.

Nearsightedness is at epidemic levels – and the problem begins in childhood

Retrieved on: 
Thursday, April 25, 2024

Some even consider myopia, also known as nearsightedness, an epidemic.

Key Points: 
  • Some even consider myopia, also known as nearsightedness, an epidemic.
  • In the United States alone, spending on corrective lenses, eye tests and related expenses may be as high as US$7.2 billion a year.
  • To answer that question, first let’s examine what causes myopia – and what reduces it.

How myopia develops

  • Optometrists have learned a great deal about the progression of myopia by studying visual development in infant chickens.
  • Just like in humans, if visual input is distorted, a chick’s eyes grow too large, resulting in myopia.
  • The more time we spend focusing on something within arm’s length of our faces, dubbed “near work,” the greater the odds of having myopia.

Outside light keeps myopia at bay

  • A 2022 study, for example, found that myopia rates were more than four times greater for children who didn’t spend much time outdoors – say, once or twice a week – compared with those who were outside daily.
  • In another paper, from 2012, researchers conducted a meta-analysis of seven studies that compared duration of time spent outdoors with myopia incidence.
  • The odds of developing myopia dropped by 2% for each hour spent outside per week.

What’s driving the epidemic

  • Globally, a big part of this is due to the rapid development and industrialization of countries in East Asia over the last 50 years.
  • Around that time, young people began spending more time in classrooms reading and focusing on other objects very close to their eyes and less time outdoors.
  • This is also what researchers observed in the North American Arctic after World War II, when schooling was mandated for Indigenous people.

Treating myopia

  • Fortunately, just a few minutes a day with glasses or contact lenses that correct for blur stops the progression of myopia, which is why early vision testing and vision correction are important to limit the development of myopia.
  • People with with high myopia, however, have increased risk of blindness and other severe eye problems, such as retinal detachment, in which the retina pulls away from the the back of the eye.
  • The chances of myopia-related macular degeneration increase by 40% for each diopter of myopia.


Andrew Herbert receives funding from NSF.

Ukraine war: Putin’s plan to fire up Zaporizhzhia power plant risks massive nuclear disaster

Retrieved on: 
Thursday, April 25, 2024

Recent reports of a series of drone strikes on Ukraine’s Zaporizhzhia Nuclear Power Plant (ZNPP) have demonstrated the serious safety and security concerns at Europe’s largest nuclear power station.

Key Points: 
  • Recent reports of a series of drone strikes on Ukraine’s Zaporizhzhia Nuclear Power Plant (ZNPP) have demonstrated the serious safety and security concerns at Europe’s largest nuclear power station.
  • It has not been confirmed who is responsible for the strikes.
  • Both Russia, which occupied ZNPP in March 2022, and Ukraine have pointed the finger at each other.

Drones strike targets

  • Attacks have included a drone strike on the oxygen and nitrogen production facility, two on the training centre and a drone shot down above a turbine hall.
  • It is clearly part of the power plant, yet is isolated and likely contains little to no nuclear material, meaning the risk of resulting nuclear accident is relatively low.
  • The IAEA has repeatedly stated that there can be no benefit to any party from a nuclear disaster at the plant.
  • Ukrainian personnel still working at ZNPP have claimed that Russia has turned the plant into a military base.
  • The IAEA continues to call for restraint and for all military activity to be halted in the vicinity of the plant.

A risky restart

  • This means the cooling water in the reactor is below 100°C and at atmospheric pressure.
  • This is safer than the previous state of “hot shutdown”, but a restart would be far worse than either of these.
  • Putting ZNPP, a plant still on the front line of an armed conflict, into operation would therefore be highly risky.
  • Chernobyl Remembrance Day commemorates the world’s worst nuclear disaster, which occurred in 1986 in what is today Ukraine.


Ross Peel is affiliated with the Centre for Science & Security Studies at King's College London.

What doesn’t kill you makes for a great story – two new memoirs examine the risky side of life

Retrieved on: 
Tuesday, April 23, 2024

She questions whether women like herself – that is, the well-educated, sexually liberated beneficiaries of second-wave feminism – are really better off than their 1940s counterparts.

Key Points: 
  • She questions whether women like herself – that is, the well-educated, sexually liberated beneficiaries of second-wave feminism – are really better off than their 1940s counterparts.
  • But it isn’t quite the avant-garde art crowd looking for anonymous vaginas to cast in their latest 16mm masterpieces either.
  • Reconstructed from the travel diary the author kept at the time, the adventure is everything you could possibly hope for in a road trip – provided you (or your daughter) aren’t the one taking it.
  • Datsun Angel proves the old adage about time and tragedy making for champagne comedy.
  • It self-consciously situates itself as a cross between the substance-induced exuberance of Jack Kerouac and Hunter S. Thompson, and the provincially impassioned politics of Australian novelist Xavier Herbert.
  • For all her progressivism, there is a note of nostalgia ringing through Broinowski’s recollections.
  • Datsun Angel harks back to a looser – dare I say, more enjoyable – university experience.
  • The narrative promises, against well-intentioned assurances to the contrary, that what doesn’t kill you will, at the very least, make for a good story later on.
  • Broinowski goes part way towards acknowledging as much when she ends her postscript with: “If you’re male and reading this, kudos.

Detachment

  • Let me borrow one instead from the middle-aged Elmore Leonard fan whom Gordon encounters in the State Library Victoria early in the book: “dickhead”.
  • Yes, that about captures it: the protagonist of Excitable Boy is an unequivocal, grade-A dickhead.
  • Fortunately for Gordon (and dickheads more generally), the affliction may be chronic, but it need not be terminal.
  • This denotes an overriding structure or cohesion that I felt somewhat lacking from the work as a whole.
  • Detachment characterises much of Gordon’s storytelling as he kicks his younger self around the back alleys of Melbourne like a half-squashed can of Monster Energy Drink.
  • To be honest, I still haven’t made my mind up if Gordon’s aversion to Aristotelian catharsis is one of the book’s virtues or vices.
  • Detail has to be controlled by some overall purpose, and every detail has to be put to work for you.
  • Detail has to be controlled by some overall purpose, and every detail has to be put to work for you.
  • It is often difficult to gauge what overall purpose the details are serving in these essays, beyond fidelity to memory.


Luke Johnson does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

In Knife, his memoir of surviving attack, Salman Rushdie confronts a world where liberal principles like free speech are old-fashioned

Retrieved on: 
Friday, April 19, 2024

A man named Hadi Matar has been charged with second-degree attempted murder.

Key Points: 
  • A man named Hadi Matar has been charged with second-degree attempted murder.
  • He is an American-born resident of New Jersey in his early twenties, whose parents emigrated from Lebanon.
  • Review: Knife: Meditations After an Attempted Murder – Salman Rushdie (Jonathan Cape) Knife is very good at recalling Rushdie’s grim memories of the attack.
  • “Let me offer this piece of advice to you, gentle reader,” he says: “if you can avoid having your eyelid sewn shut … avoid it.
  • Here, for a number of reasons, Rushdie is not on such secure ground.
  • Read more:
    How Salman Rushdie has been a scapegoat for complex historical differences

    Rushdie, who studied history at Cambridge University, described himself in Joseph Anton as “a historian by training”.

  • Indeed, a speech he gave at PEN America in 2022 is reprinted in the book verbatim.
  • For these intellectuals, principles of secular reason and personal liberty should always supersede blind conformity to social or religious authority.

Old-fashioned liberal principles

  • In Knife, though, Rushdie the protagonist confronts a world where such liberal principles now appear old-fashioned.
  • He claims “the groupthink of radical Islam” has been shaped by “the groupthink-manufacturing giants, YouTube, Facebook, Twitter”.
  • But for many non-religious younger people, any notion of free choice also appears illusory, the anachronistic residue of an earlier age.
  • Millennials and Generation Z are concerned primarily with issues of environmental catastrophe and social justice, and they tend to regard liberal individualism as both ineffective and self-indulgent.
  • A new book traces how we got here, but lets neoliberal ideologues off the hook

Suffused in the culture of Islam

  • The Satanic Verses itself is suffused in the culture of Islam as much as James Joyce’s Ulysses is suffused in the culture of Catholicism.
  • In their hypothetical conversation, the author of Knife tries to convince his assailant of the value of such ambivalence.
  • He protests how his notorious novel revolves around “an East London Indian family running a café-restaurant, portrayed with real love”.

Attachment to past traditions

  • Rushdie discusses in Knife how, besides the Hindu legends of his youth, he has also been “more influenced by the Christian world than I realized”.
  • He cites the music of Handel and the art of Michelangelo as particular influences.
  • Yet this again highlights Rushdie’s attachments to traditions firmly rooted in the past.
  • Part of James’s greatness lay in the way he was able to accommodate these radical shifts within his writing.

‘A curiously one-eyed book’

  • Particularly striking are the immediacy with which he recalls the shocking assault, the black humour with which he relates medical procedures and the sense of “exhilaration” at finally returning home with his wife to Manhattan.
  • Yet there are also many loose ends, and the book’s conclusion, that the assailant has in the end become “simply irrelevant” to him, is implausible.
  • He insists he does not want to write “frightened” or “revenge” books.
  • This was despite several brave comeback attempts by Milburn that likewise cited Pataudi as an example.
  • Knife, by contrast, is a curiously one-eyed book, in a metaphorical, as well as a literal sense.


Paul Giles does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Orphan designation: Sodium (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate Treatment of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency, 21/08/2020 Withdrawn

Retrieved on: 
Thursday, April 18, 2024

Orphan designation: Sodium (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate Treatment of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency, 21/08/2020 Withdrawn

Key Points: 


Orphan designation: Sodium (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate Treatment of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency, 21/08/2020 Withdrawn

Orphan designation: Tranilast Prevention of scarring post glaucoma filtration surgery, 27/07/2010 Positive

Retrieved on: 
Thursday, April 18, 2024

Orphan designation: Tranilast Prevention of scarring post glaucoma filtration surgery, 27/07/2010 Positive

Key Points: 


Orphan designation: Tranilast Prevention of scarring post glaucoma filtration surgery, 27/07/2010 Positive

Orphan designation: N-((R)-2,3-dihydroxypropoxyl)-3,4-difluro-2-(2-fluoro-4-iodo-phenylamino)-benzamide Treatment of neurofibromatosis type 1, 25/07/2019 Positive

Retrieved on: 
Thursday, April 18, 2024

Orphan designation: N-((R)-2,3-dihydroxypropoxyl)-3,4-difluro-2-(2-fluoro-4-iodo-phenylamino)-benzamide Treatment of neurofibromatosis type 1, 25/07/2019 Positive

Key Points: 


Orphan designation: N-((R)-2,3-dihydroxypropoxyl)-3,4-difluro-2-(2-fluoro-4-iodo-phenylamino)-benzamide Treatment of neurofibromatosis type 1, 25/07/2019 Positive

Don’t trust politicians? That may not be such a bad thing

Retrieved on: 
Wednesday, April 10, 2024

But if you’re one of the distrustful majority, that may not be such a bad thing.

Key Points: 
  • But if you’re one of the distrustful majority, that may not be such a bad thing.
  • In a 2021 survey, just 24.5% of respondents across OECD, countries said they trust political parties.
  • National polls repeatedly show similar results, particularly in the wake of scandals involving politicians misbehaving.
  • Self-evidently, trustworthy leaders are preferable – but that doesn’t mean trusting them unconditionally once they’re in power.

Trust isn’t a ‘thing’

  • But there’s no optimal survey result, and no one should expect complete trust.
  • People talk metaphorically of “building” trust, but trust isn’t a “thing” that’s literally broken and rebuilt.
  • Political trust is about an underlying “deal” that keeps a society together and functioning.
  • People disagree about whom to trust, and judgment will partly depend on which politicians promote the policies people prefer.

Government is a work in progress

  • But leadership and government are themselves problems about which people have debated for millennia, with still no universally agreed solution in sight.
  • It’s worth noting, for example, that in China, most people tell pollsters that they trust their government.
  • There may be disagreements about how best to govern, but all states practice, by necessity, some form of government.
  • As there’s no handy administrative formula for political trust, such personal and political self-examination has to persist.
  • Telling surveyors that you don’t trust politicians is a gentle and valid form of political resistance.


Grant Duncan does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

How your vision can predict dementia 12 years before it is diagnosed – new study

Retrieved on: 
Wednesday, April 10, 2024

Our latest study shows that a loss of visual sensitivity can predict dementia 12 years before it is diagnosed.

Key Points: 
  • Our latest study shows that a loss of visual sensitivity can predict dementia 12 years before it is diagnosed.
  • Our research was based on 8,623 healthy people in Norfolk, England, who were followed up for many years.
  • By the end of the study, 537 participants had developed dementia, so we could see what factors might have preceded this diagnosis.
  • People who would develop dementia were much slower to see this triangle on the screen than people who would remain without dementia.

Recognising faces

  • We have some evidence which suggests that people with dementia tend to process new people’s faces inefficiently.
  • In other words, they don’t follow the usual pattern of scanning the face of the person they are talking to.
  • So this early issue in not recognising people you have just met could be related to ineffective eye movement for new faces, rather than being a pure memory disorder.

Can eye movement improve memory?

  • Previous research on the matter is mixed, but some studies found that eye movement can improve memory.
  • In other studies, eye movements from left to right and right to left done quickly (two eye movements per second) were found to improve autobiographical memory (your life story).
  • Also, using deficits in eye movements as a diagnostic is not a regular feature, despite the possibilities in eye movement technology.


Eef Hogervorst receives funding from the Dunhill Medical Trust [email protected] receives funding from Road Safety Trust. He is affiliated with Applied Vision Association. Ahmet Begde does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.