MRI

Why you shouldn’t be afraid to start running after middle age

Retrieved on: 
Friday, April 19, 2024

As someone who started marathon running in mid-life, I know how many aches and pains (and doubts) you can have if you take on the challenge to start running at an older age.

Key Points: 
  • As someone who started marathon running in mid-life, I know how many aches and pains (and doubts) you can have if you take on the challenge to start running at an older age.
  • Hobbling around my orthopaedic hospital after my first marathon actually led me to do research on runners.
  • The high-resolution MRI scans found most of the 115 middle-aged participants had abnormalities in their knees before starting marathon training.
  • But while osteoarthritis is more common after middle age, it may actually be a lack of activity that leads to osteoarthritis.
  • Reduced muscle use, whether it is through inactivity or sarcopenia or both, also reduces the production of anti-inflammatory myokines from the muscles.
  • These chemicals are released when we exercise, and help reduce joint swelling and calm irritated joint linings.
  • This effect is pronounced in runners because running uses some of the largest muscles in the body – such as the glutes, quadriceps and hamstrings.

Where to begin

  • If you want to start running, the main message is to ease into it to reduce the risk of injury.
  • One of the best ways to ease into running in mid-life is the NHS Couch to 5K running programme.
  • It’s a free guide that will help you gradually work up towards running 5km in just nine weeks.
  • If you’ve experienced any of these problems, you’ll want to be careful when exercising to avoid further damage.


Alister Hart receives funding from 3 charities: The Rosetrees Trust, Arthroplasty for Arthritis and The Maurice Hatter Foundation.

The world’s oldest conjoined twins have died – what we know about this rare condition

Retrieved on: 
Friday, April 19, 2024

The world’s oldest conjoined twins, Lori and George Schappell, recently died, aged 62.

Key Points: 
  • The world’s oldest conjoined twins, Lori and George Schappell, recently died, aged 62.
  • Conjoined twins are incredibly rare, accounting for about one or two in every 100,000 births.
  • Because conjoined twins are so rare, it is difficult to know exactly how they come about.

Types of conjoined twins

  • There are 15 recognised types of conjoined twins, based on the various places their bodies fuse.
  • Conjoined twins are usually picked up on routine ultrasound scans performed during pregnancy.
  • Conjoined twins who are diagnosed by imaging are typically delivered by caesarean section.

Separating twins

  • One of the longest operations to separate conjoined twins, who were fused at the cranium, took more than 100 hours.
  • The earliest recorded attempt at surgical separation of conjoined twins dates back to AD945 in Armenia where conjoined brothers lived until middle age before one of them died.
  • Separating conjoined twins requires a significant amount of planning before surgery can begin, including, of course, lots of imaging such as ultrasound, CT and MRI.
  • Twins who share vital organs – or whose organs are fused – have a lower chance of a successful separation.


Adam Taylor does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Guerbet: 2023 full-year results.

Retrieved on: 
Wednesday, April 10, 2024

The Group’s operating income came to €38.7m in 2023, compared with a loss of €18.2m the previous year.

Key Points: 
  • The Group’s operating income came to €38.7m in 2023, compared with a loss of €18.2m the previous year.
  • At 31 December 2023, Guerbet's net income stood at €22.2m, compared with a loss of €41.1m in 2022.
  • Free cash flow for full-year 2023 stood at -€65.4m, having entered positive territory in the second half at +€6.6m.
  • Financially, after comfortably achieving the business and profitability targets it had set for 2023, the Group is looking to 2024 with increased confidence.

Xlife Sciences AG Announces Collaboration Agreement Between its Portfolio Company FUSE-AI GmbH and T-Systems Switzerland

Retrieved on: 
Wednesday, April 10, 2024

Xlife Sciences is pleased to announce a collaboration between its portfolio company, FUSE-AI, and T-Systems Switzerland.

Key Points: 
  • Xlife Sciences is pleased to announce a collaboration between its portfolio company, FUSE-AI, and T-Systems Switzerland.
  • T-Systems Switzerland, as a subsidiary of T-Systems International GmbH, is considered a system-relevant IT and digitalization partner in the healthcare sector in Switzerland.
  • Through this cooperation, T-Systems Switzerland distributes the AI-based solution for prostate analysis from FUSE-AI centrally in Switzerland, thereby enabling the commercialization of «Prostate.Carcinoma.ai» for radiological clinics and practices.
  • Xlife Sciences sees this partnership as a significant contribution to continuing its mission to bridge the gap between innovations and the needs of the healthcare market.

Atossa Therapeutics Presents Data from 40mg Cohort of Phase 2 EVANGELINE Clinical Trial Showing 100% Disease Control Rate After 24-Weeks of Treatment with (Z)-Endoxifen

Retrieved on: 
Tuesday, April 9, 2024

SEATTLE, April 09, 2024 (GLOBE NEWSWIRE) -- Atossa Therapeutics, Inc. (Nasdaq: ATOS) (“Atossa” or the “Company”) today announced promising safety and efficacy data from the Company’s Phase 2 EVANGELINE (Endoxifen Versus exemestANe GosEreLIn) clinical trial.

Key Points: 
  • SEATTLE, April 09, 2024 (GLOBE NEWSWIRE) -- Atossa Therapeutics, Inc. (Nasdaq: ATOS) (“Atossa” or the “Company”) today announced promising safety and efficacy data from the Company’s Phase 2 EVANGELINE (Endoxifen Versus exemestANe GosEreLIn) clinical trial.
  • Atossa is a clinical stage biopharmaceutical company developing innovative medicines in areas of significant unmet medical need in oncology with a focus on breast cancer.
  • The data, which is being presented at the American Association for Cancer Research (AACR) Annual Meeting, is from the 40mg pharmacokinetic (PK) run-in cohort of the study.
  • At 28 days, six of the seven had Ki-67 levels below 10% and stayed on treatment for an additional five months.

Reuters Publishes Pulsar Helium Film Documentary

Retrieved on: 
Friday, April 5, 2024

VANCOUVER, British Columbia, April 05, 2024 (GLOBE NEWSWIRE) -- Pulsar Helium Inc. (TSXV:PLSR | OTCQB:PSRHF) (“Pulsar” or the “Company”) is pleased to announce that a recently filmed documentary featuring Pulsar’s team onsite during the drilling of the Jetstream #1 appraisal well at the Topaz helium project (USA, MN) has been published as a dedicated segment on reuters.com.

Key Points: 
  • VANCOUVER, British Columbia, April 05, 2024 (GLOBE NEWSWIRE) -- Pulsar Helium Inc. (TSXV:PLSR | OTCQB:PSRHF) (“Pulsar” or the “Company”) is pleased to announce that a recently filmed documentary featuring Pulsar’s team onsite during the drilling of the Jetstream #1 appraisal well at the Topaz helium project (USA, MN) has been published as a dedicated segment on reuters.com.
  • Pulsar, whose assets are in the USA and Greenland, is the first private helium exploration company to work directly with the Reuters news network to highlight the critical importance of ‘safe jurisdiction’ domestically sourced primary helium.
  • Almost all electronic devices require helium during manufacture, key lifesaving medical services including MRI scanners and breathing gasses also rely on a steady and reliable source of helium.
  • Since this documentary was filmed Pulsar has identified helium contents of up to 13.8% at Topaz, making it one of the highest-grade discoveries in history.

Brainlab and Fujifilm Integrate Cutting-Edge Technology, Offering Advanced Capabilities to Neurosurgery Clinicians in the U.S.

Retrieved on: 
Thursday, April 4, 2024

ARIETTA Precision , in conjunction with a Brainlab surgical navigation system , becomes a powerful intraoperative neurosurgery solution, delivering advanced guidance and image quality for critical surgical decisions.

Key Points: 
  • ARIETTA Precision , in conjunction with a Brainlab surgical navigation system , becomes a powerful intraoperative neurosurgery solution, delivering advanced guidance and image quality for critical surgical decisions.
  • Together, the systems serve as a deeply integrated end-to-end solution providing comprehensive intraoperative information leveraging the best of both worlds in imaging and navigation.
  • This combined solution is expected to be FDA cleared and available in the United States in mid-2024.
  • * The combination of these technologies provides neurosurgeons with real-time insights through live intraoperative ultrasound (IOUS) during neurosurgical procedures.

CervoMed Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Updates

Retrieved on: 
Monday, April 1, 2024

BOSTON, April 01, 2024 (GLOBE NEWSWIRE) -- CervoMed Inc. (NASDAQ: CRVO), a clinical stage company focused on developing treatments for age-related neurologic disorders, today reported its financial results for the fourth quarter and full year ended December 31, 2023.

Key Points: 
  • Moreover, the neflamapimod treatment effects on GFAP were correlated to clinical outcomes, assessed by the CDR-SB.
  • Cash Position: As of December 31, 2023, CervoMed had $7.8 million in cash and cash equivalents as compared to $4.1 million as of December 31, 2022.
  • This increase was attributed to the RewinD-LB Phase 2b clinical study in DLB which began in the first quarter of 2023.
  • Net Loss: Net Loss was $2.2 million for the year ended December 31, 2023, compared to a net loss of $5.8 million for year ended December 31, 2022.

Synaptive Medical Receives FDA 510(k) Clearance for Near-Infrared Fluorescence Visualization, Expanding Application of Existing Robotic Exoscope

Retrieved on: 
Wednesday, March 27, 2024

Near-Infrared fluorescence now available on Modus X robotic exoscope, complementing system’s existing advanced fluorescence capabilities

Key Points: 
  • Near-Infrared fluorescence now available on Modus X robotic exoscope, complementing system’s existing advanced fluorescence capabilities
    TORONTO, March 27, 2024 (GLOBE NEWSWIRE) -- Synaptive Medical Inc., a global med tech and technology company solving surgical, imaging and data challenges, has received 510(k) clearance from the Food and Drug Administration (FDA) for its Near-Infrared fluorescence visualization module, Modus IR, adding to the existing fluorescence offering on its 4K 3D robotic exoscope, Modus X.
  • Synaptive’s Modus X features a unique fluorescence feature, powered by customized LED lighting, that enables a live fusion of white light and fluorescence views.
  • This enables visualization of fluorescent tissue and surrounding anatomy simultaneously to provide additional anatomical context while performing complex microsurgical techniques.
  • ICG causes blood to fluoresce under infrared light and is used to aid in the visualization of vessels and blood flow.

American Shared Hospital Services Pays Tribute to Ernest A. Bates, M.D., Founder and Former Chairman and CEO

Retrieved on: 
Tuesday, March 26, 2024

Ray Stachowiak, Executive Chairman of American Shared Hospital Services, remembers Dr. Bates fondly, stating, “We want to thank him for his profound contributions to the Company and to many people, including me, personally, for the past 35 years.

Key Points: 
  • Ray Stachowiak, Executive Chairman of American Shared Hospital Services, remembers Dr. Bates fondly, stating, “We want to thank him for his profound contributions to the Company and to many people, including me, personally, for the past 35 years.
  • He expanded accessibility to centers throughout the U.S. and in South America, building a solid foundation for American Shared Hospital Services’ future success.
  • Known for his intellectual curiosity, generous philanthropy, and longstanding service and dedication to American Shared Hospital Services, Dr. Bates was widely known in the healthcare industry and forged long-term friendships throughout his lifetime.
  • He previously provided consulting services to the Company pursuant to a consulting agreement from December 2021 through March 2022 before rejoining the Board in March 2022.