Add Fatty Acid to Taste: New Technology Reveals Single Cancer Cells Have Different Appetites for Fatty Acids
Fatty acids, along with glucose and amino acids, are a major energy source for cellular growth and proliferation, and abnormal fatty acid metabolism is often seen in cancer.
- Fatty acids, along with glucose and amino acids, are a major energy source for cellular growth and proliferation, and abnormal fatty acid metabolism is often seen in cancer.
- Unlike glucose and amino acids, however, the mechanisms underlying the uptake of fatty acids into cells have been lesser known and difficult to discern.
- The technical tools for measuring fatty acid uptake at the single-cell level are extremely limited.
- To profile the fatty acid uptake, the researchers chose a surrogate molecule that was structurally similar to natural fatty acids.