Effects of Triple Knockout and Human Transgenes on Survival of Kidney Xenografts in Nonhuman Primates Presented at NKF Spring Clinical Meetings
In the study, kidney xenografts from porcine donors modified to remove three major carbohydrate xenoantigens (TKO) and express up to seven human transgenes, were evaluated in a non-human primate transplant model.
- In the study, kidney xenografts from porcine donors modified to remove three major carbohydrate xenoantigens (TKO) and express up to seven human transgenes, were evaluated in a non-human primate transplant model.
- Xenografts from donors with TKO and human transgenes demonstrated prolonged survival compared to those with TKO alone, with one graft surviving over two years post-transplant.
- The NKF Spring Clinical Meetings are designed for meaningful change in the multidisciplinary healthcare teams' skills, performance, and patient health outcomes.
- The prestigious awards are presented to the recipients during the annual gathering of clinicians and kidney health professionals during the conference.