Urolithin A

Longevity Biotech, Timeline, Leads the Way in Healthy Aging Research with Groundbreaking Clinical Studies

Retrieved on: 
Monday, May 6, 2024
Biotechnology, Other Health, Diabetes, Health, Biometrics, Oncology, Vitamins, Supplements, Research, Fitness & Nutrition, Science, Clinical Trials, Cancer, Oxidative stress, American Association of Immunologists, MD, Urolithin A, Trial of the century, Doctor of Philosophy, Entrepreneurship, Prostate cancer, Neoplasm, AAI, Patient, Infection, Notifiable disease, Immune system, Longevity, CD8

Additionally, the company has partnered on two new clinical trials in collaboration with prestigious research institutions to expand its applications of Mitopure for healthy aging.

Key Points: 
  • Additionally, the company has partnered on two new clinical trials in collaboration with prestigious research institutions to expand its applications of Mitopure for healthy aging.
  • Timeline, backed by Nestlé and L'Oréal Group investments, builds on 15 years of research and multiple clinical studies.
  • "Our mission has always been to pioneer research that unlocks clinically proven interventions to help people stay healthier for longer.
  • These results open a totally new approach to directly impact our immune cells and help restore their functionality during aging."

New Publication: Scientists from National Institute on Aging, Amazentis and EPFL Publish Landmark Paper on an Essential Biological Pathway for Healthy Aging

Retrieved on: 
Thursday, December 7, 2023
Nutrition, NIA, Immunity, Research, Immune system, Ageing, Disease, Mitophagy, Urolithin A, Pac-Man, National Institute on Aging, Health, Swiss, Cognition, Mitochondrion, Human, EPFL, Facial muscles, Cell, Inflammation, Vaccine, Dietary supplement, Brain, Nature Metabolism

LAUSANNE, Switzerland, Dec. 7, 2023 /PRNewswire/ -- Timeline Nutrition announces the publication of a landmark scientific paper in Nature Metabolism, "Mitophagy in human health, aging and disease," a collaboration from the head of the National Institute on Aging (NIA), Prof. Luigi Ferrucci, and the Amazentis research team, led by Dr. Davide D'Amico. The review is coauthored by Professor Johan Auwerx from the prestigious Swiss Federal Institute of Technology (EPFL), Dr. Julie Faitg and Professor Anna Picca. 

Key Points: 
  • The review is coauthored by Professor Johan Auwerx from the prestigious Swiss Federal Institute of Technology (EPFL), Dr. Julie Faitg and Professor Anna Picca.
  • With aging often comes a lack of energy, but what if it was the other way around?
  • Impaired mitophagy can lead to chronic, low-grade inflammation and weakened immune response in the elderly, a condition known as "inflammaging."
  • To learn more about Mitopure (Urolithin A) and how Timeline Nutrition is using these insights to develop innovative nutritional products, visit www.timelinenutrition.com .

Trailblazing the Future of Healthy Aging Science: Timeline® Hosts the First Global Urolithin A Summit With a Full-day Virtual Experience

Retrieved on: 
Friday, November 3, 2023
Other Health, Other Communications, Diabetes, Health, General Health, Oncology, Communications, Other Science, Research, Fitness & Nutrition, Science, Ageing, National University of Singapore, Buck Institute for Research on Aging, Doctor of Philosophy, Princeton University, University of Rhode Island, Urolithin A, National university, University, University of Oslo, Longevity, Nursing, Timeline, MD

On November 7th, the first global Urolithin A Scientific Summit, brought to the world stage by Timeline , is set to present paradigm-shifting research in the field of longevity.

Key Points: 
  • On November 7th, the first global Urolithin A Scientific Summit, brought to the world stage by Timeline , is set to present paradigm-shifting research in the field of longevity.
  • Led by experts in the scientific community, the virtual summit, open to the general public, practitioners, and scientists, will highlight the latest research in aging, particularly focusing on Urolithin A—a breakthrough postbiotic natural molecule with a meaningful impact on health.
  • Urolithin A stands at the forefront of healthy aging with its unique potential to target several of the most important hallmarks of aging.
  • “Timeline has always been at the cutting edge and this event marks a significant milestone in our journey of raising the bar in longevity, nutrition and skin health science.”

Solgar® Cellular Nutrition Emerges to Take Longevity Cell Deep

Retrieved on: 
Tuesday, October 24, 2023
Nicotinamide adenine dinucleotide, Nicotinamide riboside, Science, Ageing, Scientific Reports, NAD, Food, Biomarker, Food and Drug Administration, Research, Cell, UA, RCT, Exercise, Development, Dietary supplement, Leg, JAMA Network Open, The Bountiful Company, Disease, Clinical trial, Urolithin A, Hand, Cysteine, Nutrient, Randomized controlled trial, NR, Oxidative stress, Longevity, Mobile phone, Glycine

HOBOKEN, N.J., Oct. 24, 2023 /PRNewswire/ -- Solgar®, a Nestlé Health Science brand and a leader in scientifically-backed vitamin and nutritional supplements for more than 70 years, today unveiled its Solgar® Cellular Nutrition line of dietary supplements developed to help fight cellular decline and promote cell health. Solgar Cellular Nutrition's products – Energy, Strength & Renewal, and Protect – target cellular decline through clinically studied ingredients, including Nicotinamide Riboside (NR), Urolithin A (UA) as well as Glycine & N-Acetyl Cysteine (GlyNAC). These products are available online through Solgar Cellular Nutrition at www.solgar.com/cellular-nutrition.  

Key Points: 
  • These products are available online through Solgar Cellular Nutrition at www.solgar.com/cellular-nutrition .
  • "These scientific advances along with new cellular nutrition research led us to develop our new line of Solgar Cellular Nutrition products.
  • These products – Energy, Strength & Renewal, and Protect – feature nutrients that work with the body's natural processes deep inside cells to help fight sources of cellular decline and promote overall cell health.
  • To learn more about Solgar Cellular Nutrition and purchase its cellular health products, please visit www.solgar.com/cellular-nutrition .

Introducing Age No More: The Ultimate Caffeinated Energy Beverage for Enhanced Vitality and Youthfulness

Retrieved on: 
Thursday, July 27, 2023
Natural Resources, Health, Specialty, Food, Beverage, Fitness & Nutrition, Other Natural Resources, Cannabis, Retail, Heart, Quercetin, Elasticity, Lion, Radical, Nicotinamide adenine dinucleotide, Andrographis, Urolithin A, Bacopa monnieri, NAD, Multimedia, Caffeine, Anti-aging product, Cordyceps, Brain Age 2: More Training in Minutes a Day!, MD, Head, CBD, Resveratrol, Dietary supplement

Age No More is not just an energy drink; it's a step toward a more vibrant and youthful you.

Key Points: 
  • Age No More is not just an energy drink; it's a step toward a more vibrant and youthful you.
  • View the full release here: https://www.businesswire.com/news/home/20230727800106/en/
    Each 12 fl Oz serving of Age No More delivers an invigorating boost with 180mg of caffeine, providing the energy you need to tackle the day head-on.
  • Additionally, Age No More incorporates 20mg of CBD sourced from full spectrum hemp, offering a sense of calm and balance to your experience.
  • NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme responsible for cellular energy production and plays a significant role in the anti-aging process.

New Study shows Urolithin A (Mitopure®) Improves Mitochondrial Health, Reduces Joint Cartilage Damage and Alleviates Pain in Osteoarthritis

Retrieved on: 
Thursday, July 7, 2022
Research, Fitness & Nutrition, Clinical Trials, Other Health, Biotechnology, General Health, Pharmaceutical, Health, Science, Other Science, Cell, Recycling, FDA, Scripps Research, Ageing, Patient, Knee, CEO, Research, Tissue, OA, Molecular medicine, DOI, Nature Medicine, Pomegranate, Multimedia, Cartilage, Osteoarthritis, Swiss Federal Institute of Technology, Swiss Federal Institute of Aquatic Science and Technology, Food, Inflammation, EPFL, Regeneration, Mitophagy, Partnership, Mitochondrion, Organelle, D Grubu, UA, List of Nature Research journals, Quality of life, Paper, Invention, European Journal of Clinical Nutrition, Urolithin A, Solution, Human, GRAS, Aging Cell, Joint, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Eating, JAMA Network Open, European Journal, Dietary supplement, Pharmaceutical industry

This is the first time a compound has been shown to improve mitochondrial health in an experimental model of osteoarthritis (OA).

Key Points: 
  • This is the first time a compound has been shown to improve mitochondrial health in an experimental model of osteoarthritis (OA).
  • View the full release here: https://www.businesswire.com/news/home/20220707005266/en/
    This study showed that treatment with Amazentis proprietary Urolithin A, Mitopure, significantly improved mitochondrial health in human cartilage cells taken from both healthy and OA knee joints.
  • Previous research has shown Mitopure can improve mitochondrial health and muscle function in both older and middle-aged human populations.
  • Osteoarthritis is the most common age-related joint disorder, characterized by degradation of cartilage and other tissues, severe pain, and impaired mobility.

New Milestone Clinical Study Shows Postbiotic Urolithin A (Mitopure™) Improves Muscle Strength and Exercise Performance in Middle Aged Adults

Retrieved on: 
Tuesday, May 17, 2022
Other Sports, Sports, Fitness & Nutrition, Clinical Trials, Other Health, Biotechnology, Pharmaceutical, Health, Science, Other Science, Inflammation, Longevity, Buck Institute for Research on Aging, Parallel Walk Test, GRAS, JAMA Network Open, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Research, Food, Doctor of Philosophy, Exercise, IRB, Swiss Federal Institute of Aquatic Science and Technology, Ageing, European Journal of Clinical Nutrition, Invention, Muscle, GameChanger, Eating, List of Nature Research journals, Mitophagy, Swiss Federal Institute of Technology, FDA, Swiss, Partnership, European Journal, Human, EPFL, Urolithin A, Nutrition, Biomarker, Health Canada, Federal Institute for Risk Assessment, Mitochondrion, Pomegranate, MD, CEO, Nature Medicine, Dietary supplement, Technology

This milestone study showed that daily intake of Amazentis proprietary Urolithin A, Mitopure, significantly improved muscle strength by 12% after four months.

Key Points: 
  • This milestone study showed that daily intake of Amazentis proprietary Urolithin A, Mitopure, significantly improved muscle strength by 12% after four months.
  • Muscle strength in the hamstring skeletal muscle was significantly increased in both 500mg (+12%) and 1,000mg groups (+9.8%).
  • Aging is associated with a decline in mitochondrial function which can lead to reduced exercise capacity, muscle endurance and strength.
  • This study is an important milestone and shows that Urolithin A could be a gamechanger in our field.

Milestone Study Shows Natural Molecule, Urolithin A, Can Improve Muscle Function and Life Expectancy in Mice With Muscle Dystrophy

Retrieved on: 
Wednesday, April 7, 2021
Other Health, Research, General Health, Pharmaceutical, Genetics, Fitness & Nutrition, Clinical trials, Science, Biotechnology, Other Science, Health, Physical therapy, Branches of biology, Coumarins, Anatomy, Muscular dystrophy, Cell biology, Mitophagy, Urolithin A, Skeletal muscle, Urolithin, Dystrophin

About 1 in 3,500 boys are born with DMD, which usually develops in childhood and significantly reduces life expectancy.

Key Points: 
  • About 1 in 3,500 boys are born with DMD, which usually develops in childhood and significantly reduces life expectancy.
  • But muscle cells taken from both human DMD patients and from mice bred to mimic the condition show significant defects in mitochondrial activity, the study finds.
  • The natural compound Urolithin A is known to activate mitophagy and improve mitochondrial health in both mice and humans.
  • The company has recently concluded two clinical trials evaluating the benefits of Urolithin A on skeletal muscle in healthy adults.

First Human Clinical Trial Results on the Anti-Aging Compound, Urolithin A, PUblished by Amazentis and Researchers From the EPFL and SIB

Retrieved on: 
Friday, June 14, 2019
Health, Biotechnology, Clinical trials, Genetics, Pharmaceutical, Research, Science, Health, Coumarins, Clinical research, Pharmaceutical industry, Articles, Urolithin A, Urolithin, Clinical trial, Validation

This is an important first clinical validation that shows Urolithin A could be a promising solution for the management of healthy muscle function during aging.

Key Points: 
  • This is an important first clinical validation that shows Urolithin A could be a promising solution for the management of healthy muscle function during aging.
  • Nestl Health Science recently announced a global partnership with Amazentis to develop products containing UA to pursue opportunities in consumer healthcare and medical nutrition.
  • The Companys proprietary technology, Urolithin A, is currently being evaluated in two Phase 2 clinical trials.
  • Amazentis has established an extensive intellectual property portfolio and know how around UA, enabling the manufacture and development of advanced nutrition products for human applications.

Nestlé Health Science invests in global strategic partnership with Amazentis to develop its new cellular nutrient Urolithin A

Retrieved on: 
Tuesday, April 2, 2019
Coumarins, Articles, Academic disciplines, Food science, Contents, Urolithin A, Urolithin, Nutrition, Dietary Supplements, Food

BRIDGEWATER, N.J., April 2, 2019 /PRNewswire/ --Nestl Health Science today announced that it has entered into a global strategic partnership with Amazentis, a Swiss-based pioneer in science-driven nutritional health.

Key Points: 
  • BRIDGEWATER, N.J., April 2, 2019 /PRNewswire/ --Nestl Health Science today announced that it has entered into a global strategic partnership with Amazentis, a Swiss-based pioneer in science-driven nutritional health.
  • Nestl Health Science will take an equity stake in Amazentis and receive global rights to use Amazentis' patented Urolithin A technology for dietary supplements, select foods and beverages, and medical nutrition products.
  • Our global strategic partnership will include a significant investment to support further research and development of Urolithin A."
  • This partnership will enable us to make this breakthrough more widely available and will support consumers in the proactive management of their cellular health."