Underactive bladder

FIU receives $3 million NIH grant to research how electric stimulation can solve bladder issues

Retrieved on: 
Tuesday, January 10, 2023
Urine, FIU College of Engineering and Computing, Nervous system, Research, Artificial intelligence, Computing, Biomedical engineering, Underactive bladder, Northeastern University, Danziger, Functional electrical stimulation, Machine learning, College, Time-invariant system, Ageing, Blood pressure, Parkinson's disease, Medical imaging, Engineering

The nervous system controls many functions in the body, including the urinary tract.

Key Points: 
  • The nervous system controls many functions in the body, including the urinary tract.
  • Controlling those nerves with electrical pulses could theoretically restore proper bladder function.
  • There are not many therapies available on the market for urinary tract issues today, said Danziger, an expert in this area of biomedical engineering.
  • This completely computerized model of the bladder and its surrounding parts will help scientists focus costly experimental efforts.

TARIS Bio Initiates New Clinical Study of TAR-302 in Overactive Bladder

Retrieved on: 
Wednesday, May 1, 2019
Urinary bladder disorders, Medical specialties, Urinary system, Surgery, RTT, Medicine, Overactive bladder, Urology, Urinary bladder, OAB, Detrusor muscle, Underactive bladder

This more robust study with an extended duration of treatment will inform the design of our Phase 2 program," said Christopher J. Cutie, M.D., Chief Medical Officer of TARIS Bio.

Key Points: 
  • This more robust study with an extended duration of treatment will inform the design of our Phase 2 program," said Christopher J. Cutie, M.D., Chief Medical Officer of TARIS Bio.
  • Study subjects will have a single dose of TAR-302 administered intravesically via catheter at the start of the study.
  • OAB can result from an underlying neurologic injury (neurogenic detrusor overactivity, or NDO) or from unclear etiology (idiopathic overactive bladder, or iOAB).
  • TARIS' lead programs in bladder cancer and overactive bladder position the company to improve patient health and redefine urologic care.