BRET

BRET MICHAELS PARTNERS WITH LIVE NATION FOR THE TRIUMPHANT RETURN OF THE MICHAELS-PRODUCED & CREATED PARTI-GRAS 2.0, THE ALL-KILLER HITS, NO FILLER, FEEL-GOOD MUSIC FESTIVAL OF THE SUMMER

Retrieved on: 
Monday, February 12, 2024
AC/DC, Twisted Sister, Concert tour, Ruoff Music Center, Singing, Woman, Freedom, Live Nation Entertainment, LOS, Buy Me a Boat, Pawn Stars, VOICE, Bret Michaels, Foreigner, Friends, DON, Highway to Hell, COUNTRY, Impractical Jokers, Your Mama Don't Dance, Sale, Bret, Mardi Gras, CMT Crossroads, Fix a Drink, Human, The Stadium Tour, CMT, Talk Dirty to Me, Hell, BRET, HIT, Poison, Music, Book, Nightclub

LOS ANGELES, Feb. 12, 2024 /PRNewswire/ -- Following the success of his first-ever solo touring festival, Parti-Gras, in 2023, Bret Michaels has partnered with Live Nation for this select exact lineup bringing the good-time summer music festival of 2024. Michaels will be belting out all of his Poison hits and be joined by some of his closest friends for an unforgettable blend of chart-toppers. Country sensation Chris Janson with this week's #1 hit "All I Need Is You," along with his "Buy Me A Boat" and "Fix A Drink," returns to join Bret on stage just like their CMT Crossroads game-changer and perform Michaels' song, "Your Mama Don't Dance" with a dueling harmonica solo. Opening the evening, the legendary Don Felder, formerly of The Eagles, plays chart-topping hits and later joins Michaels on stage. Headlining…Michaels hits the stage with unbelievable energy and his hit song "Talk Dirty To Me" and is then joined by Rock 'n' Roll Hall of Fame nominated Lou Gramm, the original voice of Foreigner, singing 3 Foreigner hits. Later in Michaels' set, Dee Snider, the high-energy voice of Twisted Sister, sings "I Wanna Rock," "We're Not Gonna Take It," and an insane version of "Highway to Hell" as well as Michaels' "Nothing But A Good Time." Michaels seamlessly conducts the evening, moving between Poison, Foreigner and Twisted Sister hits by all three original singers.

Key Points: 
  • Opening the evening, the legendary Don Felder, formerly of The Eagles, plays chart-topping hits and later joins Michaels on stage.
  • Michaels seamlessly conducts the evening, moving between Poison, Foreigner and Twisted Sister hits by all three original singers.
  • Michaels has even been known to drag fans up on stage during these arena and amphitheater shows and let them sing along.
  • Bret continues, "I created the Parti-Gras festivals first and foremost as a fan of music, bringing along friends, bands and hit songs.

New Study Reveals Strategies for Targeting “Undruggable” KRAS Mutants

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Monday, March 21, 2022
Science, Biotechnology, Research, Pharmaceutical, Oncology, Health, Genetics, Clinical Trials, Transfer, NMR, Cell, Method, Drug development, Resonance, San Francisco, DNA, Nature Chemical Biology, Multimedia, KRAS, Research, Observation, Promega, Cancer, Allele, RNA, Government, Cysteine, Industry, Biology, RAS, BRET, Cell biology, Drug discovery, Cell proliferation, Pancreatic cancer, University, Fine chemical, Pharmaceutical industry

Promega research scientists collaborated with the University of California San Francisco research group led by Dr. Kevan M. Shokat, a global leader in KRAS biology, to study the binding of potentially therapeutic molecules to common mutants of the KRAS protein.

Key Points: 
  • Promega research scientists collaborated with the University of California San Francisco research group led by Dr. Kevan M. Shokat, a global leader in KRAS biology, to study the binding of potentially therapeutic molecules to common mutants of the KRAS protein.
  • This study represents the first observation and quantification of direct target engagement of KRAS(G12D) and other hotspot oncogenic mutants of KRAS in cells using reversible binders.
  • KRAS was long considered to be undruggable until 2013 when the Shokat lab identified covalent drugs targeting KRAS(G12C), a common mutant in which a glycine amino acid is changed to a cysteine.
  • These results open new opportunities for targeting non-G12C mutants of KRAS in drug discovery.

Labroots Announces 5th Annual Drug Discovery & Development Online Event, hosted on February 23, 2022

Retrieved on: 
Thursday, February 17, 2022
Digital Solutions, Drug development, GPCR, Learning, CEO, Biomarker, Flow cytometry, Pitfalls, Social media, Science, ICON, Entrepreneurship, Doctor of Philosophy, Quantum Leap, University of Western Australia School of Medicine, Engineering, Solution, Social, Clinical trial, University of Western Australia, Technology, NASH, University, Drug discovery, Autoantibody, Advantage Business Media, Continuing education, Research, BRET, News, Industry, Institute of Health and Biomedical Innovation, Pharmaceutical industry, Online shopping, Labroots

Marking the 5th year, the symposium features another exciting lineup of invited prominent speakers spanning key topics and sharing new discoveries and advancements with the scientific community.

Key Points: 
  • Marking the 5th year, the symposium features another exciting lineup of invited prominent speakers spanning key topics and sharing new discoveries and advancements with the scientific community.
  • Drug Discovery & Development 2022 promises to deliver a comprehensive agenda including sessions ranged from novel approaches to drug discovery and preclinical development, to explorations into PK/PD and Pharmacogenomics, and lastly a peek into advancements in clinical development.
  • "Now in its 5th year, we are proud to provide a unique and highly valuable platform for inspiring interdisciplinary exchange at the forefront of drug discovery, a rapidly evolving field, via our Drug Discovery & Development virtual event," said Greg Cruikshank, Chief Executive Officer of Labroots.
  • Contributing to the advancement of science through content sharing capabilities, Labroots is a powerful advocate in amplifying global networks and communities.