Tmunity Announces First Patient Dosed in Phase 1 Clinical Trial with CART-TnMUC1
Retrieved on:
Wednesday, January 15, 2020
The MUC1 glycoprotein is a transmembrane epithelial mucin normally expressed on the apical surface of most simple glandular epithelial cells.
Key Points:
- The MUC1 glycoprotein is a transmembrane epithelial mucin normally expressed on the apical surface of most simple glandular epithelial cells.
- In tumors that arise from these cells, an alternate form of MUC1 is frequently overexpressed on the cancer cell surface.
- This clinical trial marks the third program from our portfolio to enter the clinical testing phase since our company was founded in 2015.
- The primary objective of the trial is to establish safety and the recommended Phase 2 dose of CART-TnMUC1 that can be administered with lymphodepletion.