Rotaxane

Kanazawa University research: Locking and unlocking molecular structures on demand

Retrieved on: 
Monday, February 27, 2023

KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.

Key Points: 
  • KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.
  • Rotaxanes are molecules with a two-component structure: a dumbbell-shaped part (the 'axle') threaded through a ring-like part (the 'wheel').
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now developed a new approach for controlled rotaxane dissociation and formation.
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now studied the formation and dissociation process of a palladium-containing rotaxane.

Kanazawa University research: Locking and unlocking molecular structures on demand

Retrieved on: 
Monday, February 27, 2023

KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.

Key Points: 
  • KANAZAWA, Japan, Feb. 27, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.
  • Rotaxanes are molecules with a two-component structure: a dumbbell-shaped part (the 'axle') threaded through a ring-like part (the 'wheel').
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now developed a new approach for controlled rotaxane dissociation and formation.
  • Shigehisa Akine, Yoko Sakata, and colleagues from Kanazawa University have now studied the formation and dissociation process of a palladium-containing rotaxane.

Molecular Switches Intellectual Property Landscape Report 2022: Key R&D-related Trends and Competitive Intelligence - ResearchAndMarkets.com

Retrieved on: 
Monday, January 30, 2023

The "Molecular Switches: Intellectual Property Landscape (Featuring Historical and Contemporary Patent Filing Trends, Prior Art Search Expressions, Patent Valuation Analysis, Patentability, Freedom to Operate, Pockets of Innovation, Existing White Spaces, and Claim Analysis)" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Molecular Switches: Intellectual Property Landscape (Featuring Historical and Contemporary Patent Filing Trends, Prior Art Search Expressions, Patent Valuation Analysis, Patentability, Freedom to Operate, Pockets of Innovation, Existing White Spaces, and Claim Analysis)" report has been added to ResearchAndMarkets.com's offering.
  • The "Molecular Switches: Intellectual Property Landscape" report features an extensive study of some of the key historical and contemporary intellectual property (IP) documents (featuring granted patents, patent applications and other documents), describing the various types of molecular switch interventions intended to treat a growing range of clinical conditions.
  • This report captures some of the key R&D-related trends and provides competitive intelligence on intellectual property in the field of molecular switches.
  • Key inclusions are briefly described below:
    An analytical perspective of the various patents and affiliated IP documents that have been published related to molecular switches, since 1981.

Molecular Switches Intellectual Property Landscape Report 2022: Synthetic Molecules, Such as Rotaxanes and Catenanes have Emerged as Potential Molecular Switches

Retrieved on: 
Monday, February 6, 2023

The "Molecular Switches: Intellectual Property Landscape" report features an extensive study of some of the key historical and contemporary intellectual property (IP) documents (featuring granted patents, patent applications and other documents), describing the various types of molecular switch interventions intended to treat a growing range of clinical conditions.

Key Points: 
  • The "Molecular Switches: Intellectual Property Landscape" report features an extensive study of some of the key historical and contemporary intellectual property (IP) documents (featuring granted patents, patent applications and other documents), describing the various types of molecular switch interventions intended to treat a growing range of clinical conditions.
  • In addition, synthetic molecules, such as Rotaxanes and Catenanes have emerged as potential molecular switches, as the binding sites within these mechanically interlocked molecules can be manipulated upon the application of stimuli, resulting in a shift in their structure and chemistry on cue.
  • One of the most important applications of molecular switches is to combat the challenges associated with anticancer therapies, like system toxicity, multidrug resistance, poor solubility, and membrane permeability.
  • This report captures some of the key R&D-related trends and provides competitive intelligence on intellectual property in the field of molecular switches.