Pixelation

Pixelgen Technologies Announces Peer-Review Publication on Molecular Pixelation Technology in Nature Methods

Retrieved on: 
Wednesday, May 8, 2024
Royal Society Te Apārangi, Karolinska Institute, Cancer, Protein, MPX, Cell, Pixelation, Proteomics, MD, AOCS, Doctor of Philosophy, Research, Imperial College London, DNA, PBMC, Light, Spatial analysis, Microscopy, Messenger, Paper, B cell, Immobilization, NK, Royal institute, Monocyte, Flow cytometry, Vaccine

STOCKHOLM, May 8, 2024 /PRNewswire/ -- Pixelgen Technologies, a leader in spatial proteomics for single cells, announced today that researchers from Pixelgen, the Karolinska Institute, Imperial College of London, and the Royal Institute of Technology in Sweden have demonstrated a ground-breaking sequencing-based method for identifying the relative locations of highly-multiplexed immunologically relevant proteins in single cells, in a peer-reviewed article published in Nature Methods. The Molecular Pixelation (MPX) technology used in the study is the first to demonstrate spatial proteomics of single cells without light, enabling multiplexing, throughput, and spatial resolution in 3D for proteomics-level single cell research.

Key Points: 
  • The Molecular Pixelation (MPX) technology used in the study is the first to demonstrate spatial proteomics of single cells without light, enabling multiplexing, throughput, and spatial resolution in 3D for proteomics-level single cell research.
  • The study, titled "Molecular Pixelation: Spatial Proteomics of single cells by sequencing," illustrates the ability of a DNA-barcode-based strategy to identify and visualize in 3D the spatial protein organization of immune cell receptors.
  • How immune cell surface receptors are organized relative to each other, and their behavior control many of a cell's vital functions.
  • Researchers have traditionally studied spatial surface protein organization with microscopy, using fluorophore-labeled antibodies on immobilized samples or with flow cytometry.

Pixelgen Technologies Appoints Mostafa Ronaghi to Scientific Advisory Board

Retrieved on: 
Tuesday, April 30, 2024
Stanford University, Membrane, Karolinska Institute, Genomics, Mostafa Ronaghi, Pyrosequencing, Pixelation, Clear Labs, Proteome, Imperial College London, Culture, GRAIL, Drug development, Management

STOCKHOLM, April 30, 2024 /PRNewswire/ -- Pixelgen Technologies announced today the appointment of Mostafa Ronaghi, Ph.D., to its Scientific Advisory Board.

Key Points: 
  • STOCKHOLM, April 30, 2024 /PRNewswire/ -- Pixelgen Technologies announced today the appointment of Mostafa Ronaghi, Ph.D., to its Scientific Advisory Board.
  • "Mostafa is a recognized life sciences visionary leader, with deep expertise in genomics and a tested entrepreneurial spirit," said Pixelgen CEO Simon Fredriksson.
  • "These attributes align well with Pixelgen's mission and culture, and we are honored to have him on our board.
  • "I'm thrilled to join Pixelgen's Scientific Advisory Board and look forward to working with the company's impressive team to continue developing Molecular Pixelation," Ronaghi said.

Pixelgen Technologies Launches First Molecular Pixelation Kit for 3D Spatial Analysis of Cell Surface Proteins

Retrieved on: 
Tuesday, June 13, 2023
Cell biology, SCSP, Early access, Workflow, Pixelation, 3D, NGS, Gene expression, Doctor of Philosophy, BioRxiv, MPX, Science, Protein, MD, Cell, Karolinska Institute, Drug discovery, Biology, Immunology, Health, Imperial College London, Disease, Microscope, Medical imaging, Vaccine, Illumina

STOCKHOLM, June 13, 2023 /PRNewswire/ -- Pixelgen Technologies®, the single cell spatial proteomics company, announced today the commercial launch of its first kit, based on the company's proprietary Molecular Pixelation (MPX) technology for spatial analyses of immune cell surface proteins in 3D. The Pixelgen Single Cell Spatial Proteomics Kit, Immunology Panel I, Human (Pixelgen SCSP Kit) is the first product to convey spatial polarization and colocalization of proteins on the cell surface at high-multiplex, in 3D, offering new insights into biology in health and disease.

Key Points: 
  • STOCKHOLM, June 13, 2023 /PRNewswire/ -- Pixelgen Technologies ®, the single cell spatial proteomics company, announced today the commercial launch of its first kit, based on the company's proprietary Molecular Pixelation (MPX) technology for spatial analyses of immune cell surface proteins in 3D.
  • The Pixelgen Single Cell Spatial Proteomics Kit, Immunology Panel I, Human (Pixelgen SCSP Kit) is the first product to convey spatial polarization and colocalization of proteins on the cell surface at high-multiplex, in 3D, offering new insights into biology in health and disease.
  • Cell surface proteins' location and spatial arrangement are closely linked to cell function in health and disease.
  • The Pixelgen SCSP Kit aims to close those gaps by capturing 3D maps of how proteins are spatially organized on the cell surface and in relation to one another.