Antimicrobial resistance

LexaGene’s MiQLab™ System Featured at Three Key Veterinary Tradeshows

Retrieved on: 
Friday, September 3, 2021

Beginning this September 7th and through September 26th, the MiQLab will be featured at some of the veterinary industrys landmark events in Las Vegas, Nashville, and San Antonio.

Key Points: 
  • Beginning this September 7th and through September 26th, the MiQLab will be featured at some of the veterinary industrys landmark events in Las Vegas, Nashville, and San Antonio.
  • Additionally, LexaGenes senior scientist, Dr. Eric DiBasio, MSc, PhD, will present a poster describing a study using LexaGenes MiQLab Bacterial and AMR Test for rapid detection of UTI pathogens.
  • LexaGene will showcase its MiQLab to one of the largest regional veterinary audiences and will have a podium opportunity.
  • The MiQLab system delivers excellent sensitivity, specificity, and breadth of detection and can return results in approximately two hours.

Biomeme & Predigen Merge to Enable Point-of-Care Delivery of Host Response Tests That Address Critical Unmet Needs in Healthcare

Retrieved on: 
Thursday, August 26, 2021

Predigen also has signatures for sepsis diagnosis, sepsis risk stratification, and a pipeline of biomarkers for non-infectious diseases.

Key Points: 
  • Predigen also has signatures for sepsis diagnosis, sepsis risk stratification, and a pipeline of biomarkers for non-infectious diseases.
  • That need still exists and it is a significant market opportunity that requires accurate, near-patient and rapid-result performance capabilities.
  • Combining Predigen's tests with Biomeme's portable gold-standard platforms will deliver a better diagnostic solution for use in diverse healthcare settings.
  • Over the past decade, Predigen has pioneered the use of host response to diagnose and manage disease, and as a result has developed robust host gene expression signatures that address unmet needs in medicine.

Klick Health and Lakeridge Health Unveil Free Drug Dosage Calculator to Fight Antibiotic-Resistant Bacterial Infections

Retrieved on: 
Wednesday, August 4, 2021

Today, Klick Health and Lakeridge Health introduced a technologically advanced medication dosage calculator to help pharmacists and physicians determine the correct amount of vancomycin for treating life-threatening, antibiotic-resistant, bacterial infections.

Key Points: 
  • Today, Klick Health and Lakeridge Health introduced a technologically advanced medication dosage calculator to help pharmacists and physicians determine the correct amount of vancomycin for treating life-threatening, antibiotic-resistant, bacterial infections.
  • The tool, VancoCalc , which has been in use at Lakeridge Health since December 2020, is available for free at www.VancoCalc.com .
  • We are proud to collaborate with Lakeridge Health on this important healthcare innovation, said Klick Medical R&D Scientist and project lead Anirudh Thommandram.
  • The Klick Group of companies Klick Health (including Klick Katalyst), Klick Media Group, Klick Applied Sciences (including Klick Labs), Klick Consulting, Klick Ventures, and Sensei Labs is an ecosystem of brilliant talent collectively working to maximize their people and clients full potential.

Accelerate Diagnostics Announces CE Mark and Availability in Europe of Fast Antimicrobial Susceptibility Test for Use with Existing ID Systems

Retrieved on: 
Tuesday, August 3, 2021

This is an important new option for the Company's existing Accelerate PhenoTest BC kit, which already had an ID/AST configuration that is a fully integrated solution for labs needing both fast identification and fast AST.

Key Points: 
  • This is an important new option for the Company's existing Accelerate PhenoTest BC kit, which already had an ID/AST configuration that is a fully integrated solution for labs needing both fast identification and fast AST.
  • The Accelerate Pheno system has been shown to deliver improvements in clinical outcomes including time to results, time to optimal therapy, duration of therapy and hospital length of stay.
  • Accelerate Diagnostics, Inc. is an in vitro diagnostics company dedicated to providing solutions for the global challenges of antibiotic resistance and sepsis.
  • The "ACCELERATE DIAGNOSTICS" and "ACCELERATE PHENO" and "ACCELERATE PHENOTEST" and diamond shaped logos and marks are trademarks or registered trademarks of Accelerate Diagnostics, Inc.
    For more information about the company, its products and technology, or recent publications, visit axdx.com .

Armata Pharmaceuticals Announces Chief Executive Officer Transition

Retrieved on: 
Monday, August 2, 2021

MARINA DEL REY, Calif., Aug. 2, 2021 /PRNewswire/ -- Armata Pharmaceuticals, Inc. (NYSE American: ARMP) ("Armata," "us," "our," or the "Company"), a biotechnology company focused on pathogen-specific bacteriophage therapeutics for antibiotic-resistant and difficult-to-treat bacterial infections, today announced that its current Chief Executive Officer, Todd R. Patrick, is retiring from day-to-day active management of the Company, effective today. The Company's current President and Chief Development Officer, Brian Varnum, Ph.D., has been appointed Chief Executive Officer. Mr. Patrick will continue to serve on Armata's Board of Directors and has agreed to act as a special advisor to the Company through at least 2022.

Key Points: 
  • MARINA DEL REY, Calif., Aug. 2, 2021 /PRNewswire/ -- Armata Pharmaceuticals, Inc. (NYSE American: ARMP) ("Armata," "us," "our," or the "Company"), a biotechnology company focused on pathogen-specific bacteriophage therapeutics for antibiotic-resistant and difficult-to-treat bacterial infections, today announced that its current Chief Executive Officer, Todd R. Patrick, is retiring from day-to-day active management of the Company, effective today.
  • The Company's current President and Chief Development Officer, Brian Varnum, Ph.D., has been appointed Chief Executive Officer.
  • "At the same time, we are fortunate to have someone with Brian's extensive drug development experience on the team and I would like to congratulate him on his well-deserved elevation to the Chief Executive Officer role."
  • Armata is committed to advancing its bacteriophage-based technology with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.

Entasis Therapeutics and Zai Lab Complete Patient Enrollment in the ATTACK Phase 3 Registrational Clinical Trial of Sulbactam-Durlobactam

Retrieved on: 
Tuesday, July 27, 2021

WALTHAM, Mass. and SHANGHAI, China and SAN FRANCISCO, July 27, 2021 (GLOBE NEWSWIRE) -- Entasis Therapeutics Holdings Inc. (NASDAQ:ETTX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel antibacterial products, and Zai Lab Limited (NASDAQ:ZLAB; HKEX: 9688), an innovative commercial-stage biopharmaceutical company, announced today that patient enrollment in the ATTACK Phase 3 registrational clinical trial of sulbactam-durlobactam (SUL-DUR) is now complete, with top-line data readout anticipated early in the fourth quarter of 2021.

Key Points: 
  • To our knowledge, ATTACK is the largest antibiotic-resistant, pathogen-specific registrational trial to be conducted globally and the first to focus specifically on carbapenem-resistant Acinetobacter infections.
  • Harald Reinhart, M.D., Chief Medical Officer for Autoimmune and Infectious Diseases at Zai Lab, stated, Infections caused by carbapenem-resistant Acinetobacter spp.
  • ATTACK is a Phase 3 registrational trial that will evaluate the safety and efficacy of SUL-DUR in patients with confirmed carbapenem-resistant Acinetobacter infections.
  • ATTACK is a global Phase 3 registration trial that enrolled patients at clinical sites from 17 countries.

Canadian fast-food companies failing when it comes to chicken welfare says new global report

Retrieved on: 
Tuesday, July 27, 2021

Intensive farming methods also often rely on routine antibiotic use as a quick fix solution to keep stressed and sick animals alive.

Key Points: 
  • Intensive farming methods also often rely on routine antibiotic use as a quick fix solution to keep stressed and sick animals alive.
  • This over-use of antibiotics is fueling the deadly superbug crisis that kills over 700,000 people globally a year.
  • The latestreport called" Thepeckingorder 2021" ranksthesefast food restaurantsgloballyon how they are performing on their commitment, ambition, and transparency on chicken welfare in their supply chains.
  • Three companies received zero points for their Canadian policies - Starbucks, Subway and Domino's, although they have signed up to the BCC in other markets.

Statement from the Minister of Health on the Antimicrobial Resistance (AMR) Network Report

Retrieved on: 
Tuesday, July 20, 2021

OTTAWA, ON, July 20, 2021 /CNW/ - The Honourable Patty Hajdu, Minister of Health, today issued the following statement.

Key Points: 
  • OTTAWA, ON, July 20, 2021 /CNW/ - The Honourable Patty Hajdu, Minister of Health, today issued the following statement.
  • The antimicrobial (AMR) Network recently released its final report, Strengthening Governance of the Antimicrobial Resistance Response Across One Health in Canada.
  • The AMR Network was funded by the Public Health Agency of Canada (PHAC) to explore governance models that unite diverse stakeholders in this important work.
  • Antimicrobial resistance is a complex global challenge, and this report will help all parties move toward a One Health approach to tackle this universal issue.

CHOP Researchers Establish Novel Approach for Developing New Antibiotics

Retrieved on: 
Monday, July 19, 2021

PHILADELPHIA, July 19, 2021 /PRNewswire/ --Researchers at Children's Hospital of Philadelphia (CHOP) have developed a novel method for producing new antibiotics to combat resistant bacteria.

Key Points: 
  • PHILADELPHIA, July 19, 2021 /PRNewswire/ --Researchers at Children's Hospital of Philadelphia (CHOP) have developed a novel method for producing new antibiotics to combat resistant bacteria.
  • Through an approach that would target bacteria with an antibiotic that is masked by a prodrug, which the bacteria would themselves remove, the researchers identified a method that would allow for development of new, effective antibiotics that could overcome issues of resistance.
  • "Using structure-guided design, we have developed a new way to design better antibiotics.
  • To tackle this problem, the researchers took a new approach that relied on exploiting bacterial metabolism, processes that are essential for bacteria to thrive.

A new avenue for fighting drug-resistant bacteria

Retrieved on: 
Thursday, July 15, 2021

Professor Charles Dozois from Institut national de la recherche scientifique (INRS) and doctoral student Hicham Bessaiah see a promising avenue for more effective treatment of antibiotic-resistant bacteria.

Key Points: 
  • Professor Charles Dozois from Institut national de la recherche scientifique (INRS) and doctoral student Hicham Bessaiah see a promising avenue for more effective treatment of antibiotic-resistant bacteria.
  • The bacteria have to withstand the environmental stressors in order to cause a bladder infection.
  • "Without the regulatory RNA, the bacteria is more sensitive to changes in the environment and loses its infectious capacity," explained the doctoral student.
  • The regulatory RNA sequence studied by the researchers is also found in a number of other major pathogenic bacteria.