Stowers Institute for Medical Research

BioMed Valley Discoveries Announces First Patient Dosed in Phase II Combination Trial with Ulixertinib (BVD-523), its First-in-Class and Best-in-Class ERK Inhibitor, in Combination with Hydroxychloroquine

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Monday, September 12, 2022
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KANSAS CITY, Mo., Sept. 12, 2022 /PRNewswire/ -- BioMed Valley Discoveries (BVD) announced that the first patient has been dosed in a phase II clinical trial of ulixertinib (BVD-523) in combination with hydroxychloroquine (HCQ).

Key Points: 
  • KANSAS CITY, Mo., Sept. 12, 2022 /PRNewswire/ -- BioMed Valley Discoveries (BVD) announced that the first patient has been dosed in a phase II clinical trial of ulixertinib (BVD-523) in combination with hydroxychloroquine (HCQ).
  • Ulixertinib is a first-in-class and best-in-class ERK inhibitor, with this clinical trial focusing on patients with advanced gastrointestinal malignancies and mutations in the MAPK pathway.
  • Previous efforts have also established a recommended phase 2 dose in combination with palbociclib, with additional combination efforts ongoing.
  • About BioMed Valley Discoveries (BVD): BioMed Valley Discoveries is a clinical stage biotechnology company focused on addressing unmet medical needs in a variety of therapeutic and diagnostic areas.

AMERICAN CENTURY NAMES CO-CHIEF PEOPLE OFFICERS

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Wednesday, July 20, 2022
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KANSAS CITY, Mo., July 20, 2022 /PRNewswire/ -- American Century Investments has promoted Sarah Cossa and Diane Gallagher to senior vice presidents and co-chief people officers of the firm. Working from American Century's New York City office, Cossa will serve as the HR representative on the Management Committee and lead talent acquisition, HR business partnerships, HR operations and analytics and compensation and benefits. Gallagher, based at the firm's global headquarters in Kansas City, Mo., will be a member of the Expanded Management Committee and lead employee experience and relations, learning and development and community engagement. Together, Cossa and Gallagher will lead the HR strategy as the firm attracts, retains and energizes its world-class talent and supports the development of strong workplace practices designed to further the global asset management firm's client-centric and impact-driven culture.

Key Points: 
  • KANSAS CITY, Mo., July 20, 2022 /PRNewswire/ -- American Century Investments has promoted Sarah Cossa and Diane Gallagher to senior vice presidents and co-chief people officers of the firm.
  • Cossa joined American Century Investments in 2021 as vice president, head of human resources business partnerships.
  • Gallagher originally joined American Century Investments in 1995, most recently serving as vice president, head of employee experience.
  • The Institute owns more than 40% of American Century Investments and has received dividend payments of $1.87 billion since 2000.

American Century Investments Tee'd Up Fan Participation and Prizes with NFT's Benefitting Medical Research at the American Century Championship 2022

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Wednesday, July 13, 2022
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 SOUTH LAKE TAHOE, Nev., July 13, 2022 /PRNewswire/ -- The American Century Championship annual celebrity golf tournament returned to South Lake Tahoe, Nevada, July 6-10, 2022 with some of the world's biggest celebrities, actors, and athletes. NFL legend and sportscaster, Tony Romo took the first-place win among a field of 80+ top sport stars and celebrities that included Anthony Anderson, Charles Barkley, Stephen Curry, Dylan Dreyer, Colin Jost, Patrick Mahomes, Jake Owen, Aaron Rodgers, Annika Sorenstam, Miles Teller and Justin Timberlake. The full winners list can be viewed here: https://americancenturychampionship.com

Key Points: 
  • The official charity of the 33rd annual American Century Championship is the Stowers Institute.
  • American Century Investments is a leading global asset manager focused on delivering investment results and building long-term client relationships while supporting breakthrough medical research.
  • Delivering investment results to clients enables American Century Investments to distribute over 40% of its dividends to the Stowers Institute for Medical Research, a 500-person, nonprofit basic biomedical research organization.
  • The Institute owns more than 40% of American Century Investments and has received dividend payments of $1.8 billion since 2000.

American Century Investments® Selects Marstone to Provide Digital Wealth Management Platform for New and Existing End Clients

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Wednesday, June 29, 2022
Technology, Personal Finance, Finance, Fintech, Banking, Professional Services, Software, Asset Management, Data Management, American Century Companies, Institute, Pershing, CEO, Asset, American Century, Investment, Milken Institute, Foundation, Personal, Fiserv, Fourth Industrial Revolution, Technology, Stowers Institute for Medical Research, Time, Medical research, Century, Cryptocurrency, Tutoring, Financial services, Marston Bigot Park

Marstone, Inc. , a leading digital wealth technology firm, today announced a commercial relationship with American Century Investments , the $230 billion* global asset manager, providing clients with Marstones digital wealth management platform.

Key Points: 
  • Marstone, Inc. , a leading digital wealth technology firm, today announced a commercial relationship with American Century Investments , the $230 billion* global asset manager, providing clients with Marstones digital wealth management platform.
  • As end clients investment needs change and new clients seek out advanced digital wealth solutions from their chosen financial partners, Marstone provides a modern, unified customer experience that enables clients to open and manage their unique digital advice accounts.
  • Together, Marstone and American Century are striving to provide a futureproof investment platform for the next generation of investors.
  • American Century Investments puts our clients needs first and is dedicated to helping clients achieve financial success.

American Century Championship Introduces its First-Ever NFT Charity Auction -- American Century Tees Up Fan Participation and Prizes with ACC Fantasy Golf and NFTs Benefitting Medical Research

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Tuesday, June 28, 2022
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SOUTH LAKE TAHOE, Nev., June 28, 2022 /PRNewswire/ -- A new and innovative NFT charity auction will take place during this year's prestigious American Century Championship sponsored by American Century Investments. Since 1999, American Century has been the title sponsor of the American Century Championship, the premier celebrity golf tournament that has raised more than $6 million for dozens of worthy causes and nonprofits.

Key Points: 
  • SOUTH LAKE TAHOE, Nev., June 28, 2022 /PRNewswire/ -- A new and innovative NFT charity auction will take place during this year's prestigious American Century Championship sponsored by American Century Investments.
  • "We look forward to the American Century Championship, an amazing tournament with exciting celebrities in a beautiful setting each year.
  • "This year, we are excited not just to bring back the fan-favorite ACC Fantasy Golf, but to launch our first-ever NFT charity auction.
  • Anyone can participate in the American Century Championship NFT charity auction by making a bid or purchase at www.myACCnft.com .

AMERICAN CENTURY INVESTMENTS TACKLES GENDER INVESTING GAP

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Wednesday, June 22, 2022
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KANSAS CITY, Mo., June 22, 2022 /PRNewswire/ -- American Century Investments, the $230 billion* global asset manager, is tackling the gender investing gap, in which women have roughly 80% of the retirement income of men while outliving men by five years on average.1 In addition to mobilizing organizations like the National Women's Soccer League team Kansas City Current to highlight the problem, American Century is empowering women to making progress toward closing their own investing gap through personalized insights and resources for those who pledge to make their investing move.

Key Points: 
  • KANSAS CITY, Mo., June 22, 2022 /PRNewswire/ -- American Century Investments, the $230 billion* global asset manager, is tackling the gender investing gap, in which women have roughly 80% of the retirement income of men while outliving men by five years on average.1In addition to mobilizing organizations like the National Women's Soccer League team Kansas City Current to highlight the problem, American Century is empowering women to making progress toward closing their own investing gap through personalized insights and resources for those who pledge to make their investing move .
  • To instill confidence and empower women with the knowledge and confidence they need to close their personal investing gap, American Century's campaign features investing insights from women in the investment industry.
  • The Institute owns more than 40% of American Century Investments and has received dividend payments of $1.87 billion since 2000.
  • 2022 American Century Proprietary Holdings, Inc. All rights reserved
    1Gender Pay Gap Persists Into Retirement, National Institute on Retirement Security, May 2020.

AVANTIS INVESTORS LAUNCHES U.S. LARGE CAP VALUE FUND

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Tuesday, June 21, 2022
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The fund seeks securities of companies that it expects to have higher returns by placing an enhanced emphasis on

Key Points: 
  • The fund seeks securities of companies that it expects to have higher returns by placing an enhanced emphasis on
    securities of companies it defines as high profitability or value companies.
  • Avantis U.S. Large Cap Value fund joins Avantis Investors' lineup of eight other ETFs with corresponding mutual funds: Avantis Core Fixed Income ; Avantis Core Municipal Fixed Income ; Avantis Emerging Markets Equity ; Avantis International Equity ; Avantis International Small Cap Value ; Avantis Short-Term Fixed Income ; Avantis U.S. Equity and Avantis U.S. Small Cap Value .
  • American Century Investments is a leading global asset manager focused on delivering investment results and building long-term client relationships while supporting breakthrough medical research.
  • Exchange Traded Funds (ETFs): Foreside Fund Services, LLC, Distributor, not affiliated with American Century Investment Services, Inc.
    2022 American Century Proprietary Holdings, Inc. All rights reserved.

Inside the jellyfish's sting: exploring the micro-architecture of a cellular weapon

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Tuesday, June 21, 2022
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KANSAS CITY, Mo., June 21, 2022 /PRNewswire/ -- Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis. The study, published online in Nature Communications on June 17, 2022, was led by Ahmet Karabulut, a predoctoral researcher in the lab of Matt Gibson, PhD. Their work involved the application of cutting-edge microscopic imaging technologies along with the development of a biophysical model to enable a comprehensive understanding of a mechanism that has remained elusive for over a century. Insights from the work could lead to beneficial applications in medicine, including the development of microscopic therapeutic delivery devices for humans.

Key Points: 
  • But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work?
  • Insights from the work could lead to beneficial applications in medicine, including the development of microscopic therapeutic delivery devices for humans.
  • The first phase is the initial, projectile-like discharge and target penetration of a densely coiled thread from the nematocyst capsule.
  • I realized nematocysts partially discharged their threads while the reagent I used simultaneously and instantaneously fixed the samples," said Karabulut.

APPEAL OF IMPACT INVESTING REACHES ALL-TIME HIGHS

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Wednesday, May 25, 2022
Online, American Century Companies, Education, Economics, History, Biophysical environment, Investment, Sex, Medical research, Climate change, Stowers Institute for Medical Research, Goal, Environment, Multimedia, Woman, View, Solution, Health, Geography, American Century, Adult, Social, Institute, Research, Global health, Culture, Century, Industry, Sustainable development, Climate, Man, Millennials, Proxy, Generation X, Head, Empowerment, ESG, Online gambling, Renewable energy, Financial services

KANSAS CITY, Mo., May 25, 2022 /PRNewswire/ -- The appeal of impact investing has reached all-time highs in the fifth impact investing survey by global asset manager American Century Investments®. Respondents were surveyed at the end of 2021 in the United States, United Kingdom, Germany and Australia. Responses reflected rising interest in impact investing compared to results going back to 2016 in the U.S, to 2019 for the UK and 2020 for Germany. Australia was new to the 2021 survey.

Key Points: 
  • KANSAS CITY, Mo., May 25, 2022 /PRNewswire/ -- The appeal of impact investing has reached all-time highs in the fifth impact investing survey by global asset manager American Century Investments.
  • Appeal of impact investing increases across geography, generation and gender
    In the United States, 61% of respondents found impact investing appealing, up from 51% in 2020.
  • Statistically similar shares of respondents in the U.S. (22%), UK (20%), Germany (21%) Australia (24%) indicated they found impact investing unappealing.
  • Impact investing is financial investments designed to have a positive impact on society, while providing potential long-term returns.

AMERICAN CENTURY INVESTMENTS® TEAMS UP WITH KANSAS CITY CURRENT IN ITS SECOND SEASON

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Monday, May 9, 2022
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KANSAS CITY, Mo., May 9, 2022 /PRNewswire/ -- American Century Investments, the $230 billion* global asset manager, announces its proud collaboration with National Women's Soccer League (NWSL) team Kansas City Current. Starting its second season in Kansas City with its regular season home opener Mother's Day, Sunday, May 8, KC Current shares the same goal of American Century: to elevate women in Kansas City and beyond. This season, the two organizations are teaming up for strong women and their futures: American Century will support the team while the KC Current will amplify American Century's messages and resources through their marketing channels encouraging women to close the gender investing gap.

Key Points: 
  • KANSAS CITY, Mo., May 9, 2022 /PRNewswire/ -- American Century Investments , the $230 billion* global asset manager, announces its proud collaboration with National Women's Soccer League (NWSL) team Kansas City Current .
  • Starting its second season in Kansas City with its regular season home opener Mother's Day, Sunday, May 8, KC Current shares the same goal of American Century: to elevate women in Kansas City and beyond.
  • "We are so excited about the opportunity to partner with American Century," said Angie Long, co-owner of the Kansas City Current.
  • Together, in partnership, the Kansas City Current and American Century will tell the story of the opportunity for women in the world of investments and sports."