Genetic diversity

AskBio Announces 11 Presentations at the American Society of Gene and Cell Therapy 26th Annual Meeting in 2023

Retrieved on: 
Thursday, May 11, 2023

AskBio presentations cover pre-clinical research into immune responses to AAV, data on methods to improve the efficacy of AAV-gene therapy and research into improved analytics and bioassays.

Key Points: 
  • AskBio presentations cover pre-clinical research into immune responses to AAV, data on methods to improve the efficacy of AAV-gene therapy and research into improved analytics and bioassays.
  • By targeting these therapy areas, AskBio aims to deliver breakthrough treatments that could benefit more than 35 million patients worldwide.1–7
    AskBio's presentations at ASGCT include:
    A Platform Approach for Adeno-Associated Virus Manufacturing to Support Gene Therapy Products.
  • Presented by Audry Fernandez, R&D, Asklepios BioPharmaceutical, Inc. [Oral presentation: 16:00 May 18 (Room 411)]
    Impact of Genetic Diversity on Gene Therapy Efficacy.
  • Presented by Sandro Alves, Head preclinical (France), Asklepios BioPharmaceutical, Inc. [Poster presentation: 12:00 May 19 (Poster #1261)]

Genotype analysis of six popular dog breeds finds reduced genetic diversity within subpopulations

Retrieved on: 
Tuesday, June 30, 2020

The study, Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages ,describes genetic subpopulation differentiation and related loss of genetic diversity discovered in six dog breeds: the Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever, and Shetland Sheepdog.

Key Points: 
  • The study, Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages ,describes genetic subpopulation differentiation and related loss of genetic diversity discovered in six dog breeds: the Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever, and Shetland Sheepdog.
  • Researchers examined the six popular dog breeds based on differential breeding strategies -- such as breeding for characteristics desired in 'sporting' compared to 'show' lines -- and geography using genotype analysis, finding that each of the breeds showed subpopulation differentiation contributing to a lack of genetic diversity.
  • Though breed differentiation can serve important purposes, selection must be done critically and carefully to maintain healthy genetic diversity and increase gene flow between isolated populations.
  • Based on the observed loss of genetic diversity in subpopulations of the six breeds studied, the researchers recommend that breeders take steps to encourage genetic diversity, facilitating exchange of dogs across geographical borders and avoiding unnecessary artificial boundaries between lineages.

Benson Hill Names Jason Bull as Chief Technology Officer

Retrieved on: 
Thursday, June 18, 2020

ST. LOUIS, June 18, 2020 /PRNewswire/ -- Benson Hill ,a crop innovation company dedicated to unlocking the natural genetic diversity of plants, has named Jason Bull as Chief Technology Officer to oversee all platform and product development.

Key Points: 
  • ST. LOUIS, June 18, 2020 /PRNewswire/ -- Benson Hill ,a crop innovation company dedicated to unlocking the natural genetic diversity of plants, has named Jason Bull as Chief Technology Officer to oversee all platform and product development.
  • Bull will be responsible for technology strategy and execution of the product pipeline, leveraging Benson Hill's CropOS platform and a seed-to-shelf perspective to deliver new market opportunities.
  • "Insight underpins everything we do, and crop innovation is ultimately about solving biological and information problems," said Jason Bull .
  • Benson Hill empowers innovators to develop more healthy, tasty, and sustainable food by unlocking the natural genetic diversity of plants.

Inari Adds Powerful Plant Breeding Tools Through Exclusive License to UCLA Epigenetics Patents

Retrieved on: 
Wednesday, February 13, 2019

CAMBRIDGE, Mass., Feb. 13, 2019 /PRNewswire/ --Inari, a company that is revolutionizing plant breeding by tapping natural genetic diversity, announced it has secured exclusive patent licenses for epigenetics from the University of California, Los Angeles (UCLA).

Key Points: 
  • CAMBRIDGE, Mass., Feb. 13, 2019 /PRNewswire/ --Inari, a company that is revolutionizing plant breeding by tapping natural genetic diversity, announced it has secured exclusive patent licenses for epigenetics from the University of California, Los Angeles (UCLA).
  • The agreement, through UCLA's Technology Development Group, gives Inari access to tools that will positively influence crop performance without altering a plant's genetic code.
  • Steve Jacobsen Ph.D., the UCLA professor who discovered this technology, is a scientific co-founder of Inari and a world-renowned expert in plant epigenetics, natural mechanisms that will enable Inari to re-introduce genetic diversity.
  • When applied to plant breeding, epigenetics has the potential to dramatically improve field performance and confer other beneficial characteristics to crops.