Crick

Dr. Sam Barrell CBE appointed as CEO of LifeArc

Retrieved on: 
Friday, April 19, 2024
Somerset NHS Foundation Trust, NHS, LifeArc, Francis Crick, Investment, CBE, Family medicine, Assura plc, Growth, Knowledge, PACE, Patient, Medicine, Interim, Crick, Senior, Management

LifeArc is pleased to announce the appointment of Dr. Sam Barrell, CBE, as Chief Executive Officer.

Key Points: 
  • LifeArc is pleased to announce the appointment of Dr. Sam Barrell, CBE, as Chief Executive Officer.
  • Sam will join LifeArc from the Francis Crick Institute where she is currently Deputy CEO with responsibility for strategic management and operational leadership, as well as deputising for the Director, Sir Paul Nurse.
  • Sam received a CBE in 2014 for her services to healthcare.
  • On behalf of the Board of Trustees, I am delighted to welcome Sam to LifeArc.

Unravelling DNA's structure: a landmark achievement whose authors were not fairly credited

Retrieved on: 
Tuesday, April 25, 2023
Zoology, X-ray, Male, Bell, DNA, University, Nature, DNA profiling, King's College London, Life, Bacteriophage, Gene editing, Watson, History of medicine, Double, Woman, Human, Emotion, History, Doctor of Philosophy, Yorkshire, Science, Maurice Wilkins, Crick, Death, Protein, Hershey–Chase experiment, Comfort, The Double Helix, Time, Catalysis, Chase, ARD International Music Competition, Biology, Knowledge, Cobb, Ovarian cancer, Virus, Yorkshire Evening News Tournament, News, King College, Aquaculture, Vaccine, Pharmaceutical industry, Medical imaging, Nursing, Cavendish

This knowledge of DNA allowed for a deeper understanding of how DNA stores information and how it is replicated.

Key Points: 
  • This knowledge of DNA allowed for a deeper understanding of how DNA stores information and how it is replicated.
  • For most of the past 70 years the names Watson and Crick have been synonymous with DNA.
  • And the three papers were the result of direct input from seven authors: Rosalind Franklin, Raymond Gosling, Maurice Wilkins, Alec Stokes, Herbert Wilson, James Watson and Francis Crick.

Nevertheless she persisted

    • In Watson’s 1968 book The Double Helix he frequently disparages Franklin, making negative comments about her appearance, her feminist principles and her emotions.
    • It was a photograph generated by shining x-rays through a crystal of DNA, using a technique called x-ray crystallography.
    • The image is known as Photo 51, and it contained critical information on the physical dimensions of DNA.

Things could have been different

    • One based in King College London, which included Wilkins and Franklin.
    • The article describes an exchange of information, including Franklin “checking the Cavendish model against her own x-rays’ data”.

Unlocking the role of DNA

    • Without an understanding of DNA’s role in biology Watson and Crick would not have been at all interested in DNA.
    • She produced the first x-ray images of DNA.
    • Bell’s work also gave her an inkling of DNA’s critical role in biology.
    • They used bacteriophages, viruses that infect bacteria, to show that DNA, not proteins, carried genetic information.

Taking the credit

    • The male authors of the 1953 DNA paper enjoyed long careers in academia.
    • But Chase only had a brief spell as a researcher before losing her job, for reasons that are unclear.
    • Franklin’s achievements were cut short by her death from ovarian cancer in 1958 at the age of 37.
    • And Elizabeth Fulhame introduced to science the concept of catalysis, 40 years before its “discovery” by Jons Jakob Berzelius in 1835.

Relation Therapeutics announces launch of flagship integrated wet–dry laboratory at the heart of London’s Knowledge Quarter

Retrieved on: 
Wednesday, February 22, 2023
Biotechnology, Technology, Other Health, Health, Pharmaceutical, Other Science, Research, Software, Artificial Intelligence, Genetics, Science, Knowledge, Therapy, Protein, GSK, Osteoporosis, Francis Crick Institute, Disease, Heart, Knowledge Quarter, Acquisition, Gene, Risk, Drug discovery, Khosla Ventures, Crick, Patient, Refractory, Probability, Machine learning, Francis Crick, Chairperson, Novartis, Metabolic bone disease, Roche, CSO, Fracture, Pharmaceutical industry, Relation

Relation Therapeutics, a leader in the use of high-resolution biology, machine learning and clinical insights to discover life-changing medicines, announced today the opening of their flagship integrated wet–dry laboratory.

Key Points: 
  • Relation Therapeutics, a leader in the use of high-resolution biology, machine learning and clinical insights to discover life-changing medicines, announced today the opening of their flagship integrated wet–dry laboratory.
  • The laboratory and offices comprise 5,500 sq ft, located at the heart of London’s Knowledge Quarter, in close reach of collaborators and partners including globally renowned academic research centres and major pharma companies.
  • The new space is another step forward in realising Relation’s ambition to establish a novel transformational approach to drug discovery.
  • The integrated wet–dry laboratory’s unique value for drug discovery comes from efficiently combining the most sophisticated functional genomic techniques with extraordinary computational power and machine learning.

G3 Therapeutics and Juvenescence Limited Announce the Formation of Juvenomics, a Visionary Company Founded on Applying Deep Molecular Profiling and Deep Learning to Tackle Aging

Retrieved on: 
Monday, June 1, 2020
Biotechnology, Pharmaceutical, Finance, Health, Data management, Professional services, Technology, Clinical trials, Fellows of the Royal Society, DNA, English people, British people, Francis Crick, Materialists, Panspermia, Crick, MD, Awards, G3 Therapeutics, Juvenescence Limited

Juvenomics is also proud to announce the appointment of Dr. David Roblin MD FMedSci to its Board of Directors.

Key Points: 
  • Juvenomics is also proud to announce the appointment of Dr. David Roblin MD FMedSci to its Board of Directors.
  • He is currently COO at Juvenescence and the Chair of Scientific Translation at the Francis Crick Institute.
  • Gregory Bailey MD, Founder and CEO of Juvenescence Limited commented:
    At Juvenescence, we are very excited about this opportunity to work with G3.
  • G3 Therapeutics has assembled a revelatory platform that utilizes deep phenotyping, deep molecular profiling and deep learning for the discovery, genetic validation and development of novel drug targets.

Startup Hadean to Accelerate Francis Crick Virus Simulation With Breakthrough Compute Platform

Retrieved on: 
Wednesday, April 15, 2020
London boroughs, London Borough of Camden, Science and technology in the United Kingdom, DNA, Dream, Francis Crick, Materialists, Panspermia, Crick, Hadean, Scientific modelling, Virus

LONDON, April 15, 2020 /PRNewswire/ --Startup Hadean have partnered with the Francis Crick Institute to accelerate the development of a single, massive scale simulation of how viruses, like COVID-19 spread.

Key Points: 
  • LONDON, April 15, 2020 /PRNewswire/ --Startup Hadean have partnered with the Francis Crick Institute to accelerate the development of a single, massive scale simulation of how viruses, like COVID-19 spread.
  • The joint project between the globally renowned Francis Crick Institute and Hadean will integrate complex data on how viruses develop in humans with city-wide contagion modelling.
  • Hadean's distributed hyper-compute platform and spatial simulation solution, Aether Engine, enable faster modelling at greater scale, whilst reducing the overhead needed to manage computation requirements for massive data set simulation.
  • Craig Beddis, Hadean CEO said "our partnership with the Francis Crick Institute is a critical step forward in defeating the spread of viruses such as COVID-19.

Startup Hadean to Accelerate Francis Crick Virus Simulation With Breakthrough Compute Platform

Retrieved on: 
Wednesday, April 15, 2020
London boroughs, London Borough of Camden, Science and technology in the United Kingdom, DNA, Dream, Francis Crick, Materialists, Panspermia, Crick, Hadean, Scientific modelling, Virus

LONDON, April 15, 2020 /PRNewswire/ --Startup Hadean have partnered with the Francis Crick Institute to accelerate the development of a single, massive scale simulation of how viruses, like COVID-19 spread.

Key Points: 
  • LONDON, April 15, 2020 /PRNewswire/ --Startup Hadean have partnered with the Francis Crick Institute to accelerate the development of a single, massive scale simulation of how viruses, like COVID-19 spread.
  • The joint project between the globally renowned Francis Crick Institute and Hadean will integrate complex data on how viruses develop in humans with city-wide contagion modelling.
  • Hadean's distributed hyper-compute platform and spatial simulation solution, Aether Engine, enable faster modelling at greater scale, whilst reducing the overhead needed to manage computation requirements for massive data set simulation.
  • Craig Beddis, Hadean CEO said "our partnership with the Francis Crick Institute is a critical step forward in defeating the spread of viruses such as COVID-19.