ExeVir Bio and VIB Announce Data on a New Therapy for Prevention and Treatment for COVID-19
Nearly all SARS-CoV-2 neutralizing antibodies that have been used in the clinic show substantial loss of potency against currently circulating variants.
- Nearly all SARS-CoV-2 neutralizing antibodies that have been used in the clinic show substantial loss of potency against currently circulating variants.
- It targets a conserved region in the spike S2 subunit that is essential for viral entry.
- It neutralizes all previous and current variants of concern and the currently most frequently circulating variants, including XBB, XBB.1.5, BQ.1.1 and BF.7.
- The pharmacodynamic and safety properties of candidate drug molecules based on these S2-binding single domain antibodies were extensively evaluated in vitro and in vivo by ExeVir Bio.