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Genes that Form Specific Bones In the Womb Heal them Later in Life

Retrieved on: 
Monday, March 20, 2023

NEW YORK, March 20, 2023 /PRNewswire/ -- Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.   

Key Points: 
  • NEW YORK, March 20, 2023 /PRNewswire/ -- Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.
  • Such adjustments guide immature stem cells as they multiply and mature in the womb, say the study authors, to become heart muscle, nerves, bones, etc., and in the right places.
  • Bone is among the tissues that keep pools of stem cells on hand into adulthood, ready to mature into needed replacement cells that maintain healthy tissue and heal broken bones.
  • During aging, such stem cells become depleted, the researchers say, resulting in weaker bones that are more likely to fracture and slower to heal.