Tibia

• "Meanwhile, efforts to stimulate production of certain blood cell types may be dramatically improved by focusing on specific bone types."
• The key discoveries reported in the paper include:
  New tools allowing visualization of blood production inside the bone, allowing defining the basic anatomy of blood cell formation.
• Among several examples: blood loss triggered rapid red blood cell production in the sternum, tibia, vertebrae, and humerus -- but not in the skull.
• Importantly, the process developed for this study allowed the team to analyze blood cell development in multiple parts of the skeleton.

• BETHLEHEM, Pa., Feb. 12, 2024 /PRNewswire/ -- Tyber Medical LLC, a leading orthopedic device manufacturer providing private label orthopedic implants for the trauma, extremity, and spine markets, has received a U.S. Food and Drug Administration (FDA) 510(k) approval for its Proximal Tibia Plating System.
• The Tyber Medical System consists of two indication categories: Complete Articular and Partial Articular Fractures.
• The Tyber Medical Proximal Tibial Plating System is engineered to accommodate surgeon preferences, increase procedural efficiency, and enhance plate fit and screw placement.
• Lisa Boyle, Director of Regulatory Affairs commented "With the clearance of the Proximal Tibial Plating System and its sub-categories, Tyber Medical remains unwavering in our commitment to providing cutting edge orthopedic solutions."

• And that suggests their demise came suddenly, with the impact of a giant asteroid.
• The discovery of the 180km-wide Chixculub asteroid impact crater in Mexico suggested a sudden extinction of dinosaurs and other species, driven by the impact.
• But others have argued that a long, slow decline in dinosaur diversity contributed to their extinction.
• It’s not just that dinosaur fossils are so rare; the fossil record is also patchy.
• Because it’s such a huge landmass, Africa probably had far more dinosaur species than North America.

What we’ve found

• Dinosaurs may have swum out to islands searching for food, as deer and elephants do today, and some might have drowned.
• Other dinosaurs might have been washed out to sea by floods or storms, or drowned in rivers that carried them downstream to the ocean.
• And so, studying marine beds, and working over many years, we’ve slowly put together a picture of Africa’s last dinosaurs, bone by bone.
• It was smaller than Chenanisaurus, about five metres long – small by dinosaur standards, but large compared to modern predators.
• If so, that means dinosaurs were cut down in their prime; burning out rather than fading away.

What our findings show

• For over 100 million years, they evolved and diversified, producing a remarkable range of species: predators, herbivores, aquatic species, even flying forms, the birds.
• Then in a single, catastrophic moment, everything was wiped out in the months of darkness caused by dust and soot from the impact.

Nicholas R. Longrich does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

• In children, human growth hormone therapy has been used for decades to treat growth hormone deficiency due to underlying medical conditions such as Turner syndrome, very small weight at birth, Prader-Willi syndrome and chronic renal insufficiency.
• Given the volume of patients we treat, we were able to investigate the relationship between tibia growth plate fractures and growth hormone therapy in pediatric patients."
• Therefore, the odds of taking growth hormone therapy were 15 times higher among patients with proximal tibia physeal avulsion fractures than the comparison group.
• "Further research is required to tease out whether limiting specific high-impact sports will mitigate the risk of tibia growth plate fractures in active children and adolescents."