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Feinstein Institutes Researchers Discover Defensive Molecules That Can Worsen Inflammation in Sepsis

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Friday, July 21, 2023

In a potential therapeutic breakthrough, investigators at The Feinstein Institutes for Medical Research have identified a type of white blood cell that can worsen inflammation in sepsis and opens up new avenues of research to treat the deadly condition.

Key Points: 
  • In a potential therapeutic breakthrough, investigators at The Feinstein Institutes for Medical Research have identified a type of white blood cell that can worsen inflammation in sepsis and opens up new avenues of research to treat the deadly condition.
  • (Credit: Feinstein Institutes)
    Results of the study, led by Ping Wang, MD , professor and chief scientific officer at the Feinstein Institutes, were published today in the Journal of Clinical Investigation .
  • “APANs, when triggered, can result in devastating circumstances for patients who have sepsis,” said Dr. Wang, senior author of the paper.
  • Last year, Dr. Wang and co-principal investigators at the Feinstein Institutes received $3.8 million from the National Institute of Health to study sepsis and radiation exposure.