Isoflavone

• According to the NCBI, nutraceuticals are used to improve health, slow the ageing process, prevent chronic diseases, and increase life expectancy.
• According to NIH researchers, nutraceuticals have attracted significant interest in the healthcare industry due to their therapeutic benefits.
• The nutraceuticals market size was worth around USD 353 billion in 2022 and is estimated to hit approximately USD 700 billion by 2030.
• The global nutraceuticals market is anticipated to record massive growth over the forecast period owing to the humungous consumption of functional foods has translated into a rise in the demand for nutraceuticals.

• Hot flushes and night sweats are the most common of these, affecting 75% of women and the symptom for which most women seek treatment.
• In Australia it is estimated more than one-third of women seek complementary or alternative medicines to manage menopausal symptoms.

What’s on the market?

• They include everything from mind-body practices (hypnosis, cognitive behavioural therapy and meditation) to alternative medicine approaches (traditional Chinese medicine and acupuncture) and natural products (herbal and dietary supplements).
• There is some evidence to support the use of hypnosis and cognitive behaviour therapy for the treatment of hot flushes.
• But there is less certainty around the benefit of other commonly used complementary and alternative medicines, particularly nutritional supplements.

What are phytoestrogens?

• There are numerous types including isoflavones, coumestans and lignans.
• In the latter category, extracts from soy and red clover yield isoflavones and flaxseed gives us lignans.

What does the evidence say?

• Overall, evidence regarding the benefit of phytoestrogens for hot flushes is fairly mixed.
• A Cochrane review synthesised study results and failed to find conclusive evidence phytoestrogens, in food or supplement form, reduced the frequency or severity of hot flushes or night sweats in perimenopausal or postmenopausal women.
• Another recent study showed marked reductions in hot flushes in women following a low fat, vegan diet supplemented with daily soybeans.

Can phytoestrogens help the psychological symptoms of menopause?

• Less research has explored whether phytoestrogens improve psychological symptoms of menopause, such as depression, anxiety and brain fog.
• A recent systematic review and meta-analysis found phytoestrogens reduce depression in post- but not perimenopausal women.

The bottom line

• If you do wish to see if they might work for you, start by including more phytoestrogen-rich foods in your diet.
• Examples include tempeh, soybeans, tofu, miso, soy milk (from whole soybeans), oats, barley, quinoa, flaxseeds, sesame seeds, sunflower seeds, almonds, chickpeas, lentils, red kidney beans and alfalfa.
• Try including one to two serves per day for around three months and monitor symptoms.

• The Global Flavonoids Market size is expected to reach $1.5 billion by 2028, rising at a market growth of 12.1% CAGR during the forecast period.
• Since they are not directly engaged in growth and development, they are also referred to as "secondary metabolites."
• According to their chemical makeup, flavonoids can be divided into 12 major subclasses, six of which are important from a dietary perspective.
• The attention that flavonoids have gotten for their benefits has led to increased demand for this over-the-counter supplement.

• The "Isoflavones Market Intelligence Report - Global Forecast to 2027" report has been added to ResearchAndMarkets.com's offering.
• The Global Isoflavones Market is projected to reach USD 2,014.11 million by 2027 from USD 1,412.48 million in 2021, at a CAGR 6.09% during the forecast period.
• In this report, the years 2019 and 2020 are considered as historical years, 2021 as the base year, 2022 as the estimated year, and years from 2023 to 2027 are considered as the forecast period.
• The report on isoflavones identifies key attributes about the customer to define the potential market and identify different needs across the industry.