IUD

3Daughters Named “Startup of the Year” at BioLabs Philadelphia Investor Day 2024

Retrieved on: 
Friday, April 19, 2024
Pain, Attention, Hormone, IUD, Safety, Woman, Birth control

MANSFIELD, Mass., April 19, 2024 (GLOBE NEWSWIRE) -- 3Daughters , Inc., a clinical development company fueling evolutionary healthcare for women, was voted the “Startup of Year” by top life science investors and venture capitalists at the 2024 BioLabs Investor Day that took place in Philadelphia on April 16, 2024.

Key Points: 
  • MANSFIELD, Mass., April 19, 2024 (GLOBE NEWSWIRE) -- 3Daughters , Inc., a clinical development company fueling evolutionary healthcare for women, was voted the “Startup of Year” by top life science investors and venture capitalists at the 2024 BioLabs Investor Day that took place in Philadelphia on April 16, 2024.
  • BioLabs Investor Day events are carefully curated, invite-only pitch events where top startups are connected directly with major investors from across the eastern seaboard.
  • Out of 78 applications submitted, 3Daughters was one of 15 companies selected to pitch at the event.
  • Following a competitive pitch process, participating investors anonymously selected 3Daughters as the “Startup of The Year” for 2024.

Social media will tell you birth control causes mental health issues, weight gain and infertility – here are the facts

Retrieved on: 
Tuesday, April 9, 2024
Research, Depression, Health, Friends, Faculty, Birth, Infertility, Intrauterine device, Menstrual cycle, Depo, Weight gain, Patient, IUD, Birth control, Social media, Mental health, Fertility, Medroxyprogesterone acetate, Life, Quarterlife, Adolescence, Systematic review, Woman, Progesterone, Family

Some women are reportedly even stopping their birth control as a result of misleading posts they’ve seen on TikTok and Instagram.

Key Points: 
  • Some women are reportedly even stopping their birth control as a result of misleading posts they’ve seen on TikTok and Instagram.
  • These three common misconceptions about birth control are cropping up online and need to be put in context:

1. Contraception causes depression

  • Countless videos on social media discuss the effect hormonal contraceptives have on mental health – with some creators claiming birth control causes mood changes and even depression.
  • Although there’s some correlation between mental health and some forms of contraception, there are many factors at play.
  • The articles in this series explore the questions and bring answers as we navigate this turbulent period of life.
  • The evidence suggests depression is more common in adolescent girls – and diminishes after the first two years of taking these forms of birth control.
  • At present, there’s little conclusive evidence that contraception (both hormonal and non-hormonal types) cause mental health problems.

2. Contraception causes weight gain

  • Another common social media claim is that birth control causes weight gain.
  • There is one form of contraception that is linked to weight gain.
  • The Depo-Provera injection, which is administered every 12 weeks, has been proved to cause weight gain.


This weight gain may be due to the progesterone in the shot, which can cause people to feel hungrier – potentially leading to overeating and weight gain. If you’re concerned about potential weight gain, the injection is not the only form of contraception available. Other forms of hormonal and non-hormonal contraceptives have not been shown to affect your weight.

3. Birth control lowers your fertility

  • Another common claim on social media is that birth control causes fertility issues.
  • Research shows hormonal contraceptives have no affect on fertility.
  • Again, evidence shows that IUDs pose no risk to fertility.
  • A systematic review reports no specific differences in fertility between hormonal and non-hormonal IUDs.


Christopher O'Sullivan does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

3Daughters Announces Three New Appointments to Board of Directors

Retrieved on: 
Wednesday, March 13, 2024
Quotient, Thakeham, Alnylam Pharmaceuticals, CDMO, Birth, Labs, GSK plc, Pharmacy, University, Novartis, Dana–Farber Cancer Institute, IUD, University College London, Embryology, IND, MBA, Woman, Doctor of Philosophy, Intrauterine device, Therapy, Drug development, Allergan, Amersham plc, Takeda Oncology, Chief Justice of Hungary, Pharmacia, Birth control

Miles, Ph.D., and Sarah J. Stevens, Ph.D., to serve on the Company’s Board of Directors.

Key Points: 
  • Miles, Ph.D., and Sarah J. Stevens, Ph.D., to serve on the Company’s Board of Directors.
  • An IND for 3D-001 will be filed this year followed by a Phase 1 clinical trial.
  • Mary Beth Cicero, CEO of 3Daughters, expressed her enthusiasm about the new additions to the board: "We are incredibly excited to have the collective strengths of Michele, Sarah, and Vin on our Board of Directors.
  • With this first product, 3Daughters expects to disrupt the IUD market and establish a position as a major innovator in women's healthcare.

Navigating Birth Control: Expert Advice from Dr. Bana Kashani, OB-GYN

Retrieved on: 
Friday, March 29, 2024
Women, Other Communications, Baby, Maternity, Communications, Practice Management, Family, Health, Consumer, General Health, Birth, Pregnancy, Infertility, Q&A, Intrauterine device, Condom, Menstrual cycle, Sterilization, IUD, Ovulation, Research, Fertility, Pelvic inflammatory disease, Hormonal contraception, Tubing (recreation), STI, Woman, USB On-The-Go, Birth control

In a rapidly evolving landscape of reproductive health, navigating the variety of birth control options can be overwhelming.

Key Points: 
  • In a rapidly evolving landscape of reproductive health, navigating the variety of birth control options can be overwhelming.
  • “When choosing a birth control method, it's essential to consider factors such as efficacy, convenience, side effects, and personal preferences.
  • Dr. Kashani sheds light on various birth control methods in the following Q&A:
    What are the different types of birth control methods available?
  • There is limited evidence to suggest that using birth control methods for an extended period negatively impacts fertility.

3Daughters Successfully Closes Over $2 million in First Tranche of Seed Financing Round

Retrieved on: 
Monday, January 22, 2024
Abele, Entrepreneurship, Woman, Reproductive rights, Physics, Argosy Foundation, Intrauterine device, Partnership, Birth, Uterus, IND, IUD, Pain, Copper, Birth control

MANSFIELD, Mass., Jan. 22, 2024 (GLOBE NEWSWIRE) -- 3Daughters , a clinical development company fueling evolutionary healthcare for women, announces closing of the first tranche in excess of $2 million in a Seed Round.

Key Points: 
  • MANSFIELD, Mass., Jan. 22, 2024 (GLOBE NEWSWIRE) -- 3Daughters , a clinical development company fueling evolutionary healthcare for women, announces closing of the first tranche in excess of $2 million in a Seed Round.
  • 3Daughters has a unique and frameless delivery platform, based on physics and geometry, for targeted therapy directly into the uterus.
  • 3D-001, a novel IUD containing copper, a proven spermicide for contraception, is the first product resulting from the technology.
  • This investment marks the next chapter for 3Daughters and allows us to execute our streamlined development plans to move into the clinic.

Danco Statement on Filing of Cert Petition, September 8, 2023

Retrieved on: 
Friday, September 8, 2023
REMS, Pregnancy, Fifth Circuit Four, Reproductive rights, Bleeding, Allergy, Medication, Diarrhea, Internal bleeding, Pharmacy, Mifepristone, IUD, Gestational age, Misoprostol, Health care, Fever, Danco, Weakness, Woman, Prescription, Angioedema, Prostaglandin, Hypovolemic shock, Patient, Abdominal pain, Sepsis, Rash, Tachycardia, Vomiting, Leukocytosis, Administration, Death, Syncope, Vaginal bleeding, Dizziness, Fungal infection, United States Court of Appeals for the Fifth Circuit, Anaphylaxis, Anemia, Supreme court, Law of the United Kingdom, Nausea, Court, Genetically modified bacteria, FDA, Headache, Hematocrit, Zauderer v. Office of Disciplinary Counsel of Supreme Court of Ohio, Safety, Full, Pharmaceutical industry, Birth control, Vaccine, Dentistry, Nursing, Infection

Danco remains confident in the safety and effectiveness of Mifeprex® under the 2023 REMS that currently governs its use.

Key Points: 
  • Danco remains confident in the safety and effectiveness of Mifeprex® under the 2023 REMS that currently governs its use.
  • The changes in 2016 and 2021—approved by FDA after careful analysis—have expanded the availability and use of Mifeprex®, providing crucial individual and public health benefits.
  • Serious and sometimes fatal infections and bleeding occur very rarely following spontaneous, surgical, and medical abortions, including following MIFEPREX use.
  • The frequency of adverse reactions varies between studies and may be dependent on many factors including the patient population and gestational age.

Emergency contraception: here’s what you probably don’t know but should

Retrieved on: 
Thursday, August 31, 2023
Nausea, Acetate, Pregnancy, Headache, Life, STI, Friends, IUD, Pharmacy, Tubing (recreation), Method, Ovulation, Birth, Abortion, Levonorgestrel, Uterus, Tablet, Vomiting, Dizziness, Risk, Fertility, Quarterlife, Ulipristal acetate, Menstrual cycle, Chronic pain, Condom, NHS, Mental health, Family, Environment, Birth control

Whatever the reason, if you need to prevent an unplanned pregnancy you might decide to use emergency contraception.

Key Points: 
  • Whatever the reason, if you need to prevent an unplanned pregnancy you might decide to use emergency contraception.
  • For emergency IUD fittings, you need to go to a contraceptive and sexual health clinic, or your GP or gynaecologist.
  • This article is part of Quarter Life, a series about issues affecting those of us in our twenties and thirties.

How does it work?

    • Levonorgestrel and ulipristal both work by delaying ovulation.
    • This means that if there are sperm inside the fallopian tubes, there won’t be an egg for them to meet and fertilise.
    • In a typical menstrual cycle, you’re most at risk of pregnancy on days nine to 14.
    • But even if you’re more than halfway through your typical monthly cycle, these tablets can still work.

How effective is it?

    • While it’s the most effective form of emergency contraception, it can be uncomfortable or even painful to have an IUD fitted.
    • It’s at least 95% effective at stopping pregnancies when taken within this time frame.
    • Levonorgestrel is 95% effective at preventing pregnancy if taken within 24 hours of unprotected sex.
    • But both tablets are up to 95% effective at stopping pregnancies when taken soon after unprotected sex.

What should you expect?

    • It may also cause your next period to begin earlier or later than normal.
    • Ectopic pregnancy (when a fertilised egg implants in a fallopian tube) may be possible if emergency contraception fails.
    • It’s also worth noting that emergency contraceptives have no effect on long-term fertility and can be used even if you plan to have children later on.

Danco Statement on 5th Circuit Ruling, August 16, 2023

Retrieved on: 
Thursday, August 17, 2023
REMS, Pregnancy, Reproductive rights, Bleeding, Allergy, Medication, Diarrhea, Internal bleeding, Pharmacy, Mifepristone, IUD, Gestational age, Misoprostol, Health care, Fever, Danco, Weakness, Woman, Prescription, Multimedia, Prostaglandin, Angioedema, Hypovolemic shock, Patient, Abdominal pain, Sepsis, Rash, Tachycardia, Tablet, Vomiting, Leukocytosis, Congress, Death, Administration, Syncope, Vaginal bleeding, Dizziness, United States Court of Appeals for the Fifth Circuit, Fungal infection, Anaphylaxis, Anemia, Supreme court, Nausea, Genetically modified bacteria, FDA, Headache, Hematocrit, Zauderer v. Office of Disciplinary Counsel of Supreme Court of Ohio, Safety, Full, Birth control, Pharmaceutical industry, Vaccine, Dentistry, Nursing, Infection

NEW YORK, Aug. 16, 2023 /PRNewswire/ -- The Fifth Circuit panel's decision is inconsistent with established Supreme Court principles governing standing and administrative law challenges.

Key Points: 
  • NEW YORK, Aug. 16, 2023 /PRNewswire/ -- The Fifth Circuit panel's decision is inconsistent with established Supreme Court principles governing standing and administrative law challenges.
  • Danco remains confident in the safety and effectiveness of Mifeprex® and committed to making the drug available as broadly as possible.
  • Danco will continue to be at the forefront of this fight, working closely with the reproductive rights community and pharmaceutical industry, as this case moves forward.
  • Over 5 million women have used Mifeprex® in the United States since its approval for the termination of early pregnancy in 2000.

Curae Pharma360 Promotes Autumn Ehnow to Chief Executive Officer

Retrieved on: 
Tuesday, June 13, 2023
Levonorgestrel, Policy, MD, Operational definition, IUD, Doctor of Philosophy, OTC, Management, Pharmaceutical industry, Growth, Cura del Popolo

SAN FRANCISCO, June 13, 2023 /PRNewswire/ -- Curae Pharma360 (Curae), a mission-driven pharmaceutical company strengthening access to and affordability of life-changing generic medicines, announced today it has promoted Autumn Ehnow to Chief Executive Officer. A founding leader of Curae and its Chief Operating Officer since the company's inception last year, Ehnow will continue to serve as Executive Vice President, Policy & Strategic Market Access at Medicines360, the nonprofit parent company of Curae.

Key Points: 
  • Ehnow's Leadership and Operational Expertise to Drive Curae's Growth, Partnerships, and Product Portfolio
    SAN FRANCISCO, June 13, 2023 /PRNewswire/ -- Curae Pharma360 (Curae), a mission-driven pharmaceutical company strengthening access to and affordability of life-changing generic medicines, announced today it has promoted Autumn Ehnow to Chief Executive Officer.
  • A founding leader of Curae and its Chief Operating Officer since the company's inception last year, Ehnow will continue to serve as Executive Vice President, Policy & Strategic Market Access at Medicines360, the nonprofit parent company of Curae.
  • Ehnow, who had a major role establishing the commercial operations at Curae, brings two decades of experience as a pharmaceutical and nonprofit leader to the CEO role.
  • "Autumn's expertise is exactly what Curae needs in a leader," said Andrea Olariu, MD, PhD, CEO of Medicines360.

Want long-term contraception? There are more effective options than the pill. But they can be hard to find

Retrieved on: 
Thursday, June 1, 2023
Workforce, Aura, Migraine, Pregnancy, Senate, Ovary, IUD, Birth, Nursing, Intrauterine device, Uterus, Government, Hormone, Pain, Medicare, Abortion, Swimming, Copper, Hysterectomy, Smoke, Magnetic resonance, Remuneration, GP, PBS, Skin, Breast cancer, Birth control, Hormonal intrauterine device

Australians’ access to a range of contraceptive options depends on where they live and how wealthy they are.

Key Points: 
  • Australians’ access to a range of contraceptive options depends on where they live and how wealthy they are.
  • A recent parliamentary inquiry recommends ways to end this “postcode lottery” for people who want to use long-acting reversible contraception.
  • There are several types of long-acting reversible contraception: the hormonal contraceptive implant, the hormonal intrauterine devices (IUD) and copper IUDs.

How do they work?

    • It releases a progestogen hormone which prevents monthly egg release from the ovary for up to three years.
    • IUDs are small T-shaped devices which are inserted into the uterus.
    • Hormonal IUDs contain a progestogen hormone and mainly work by thickening the cervical mucus and preventing sperm from swimming up into the uterus.

They have additional benefits for some users

    • As well as better protection from pregnancy, some long-acting reversible contraception methods have other benefits.
    • The hormonal IUD, Mirena, for example, reduces heavy menstrual bleeding.
    • This includes people with hormone-driven cancers such as breast cancer, for whom any hormonal contraceptive would be considered unsafe.

Why aren’t they more available?

    • Out-of-pocket IUD insertion-related costs can also vary from zero to hundreds of dollars if people don’t have access to publicly funded services.
    • Here’s what to expect

      On the supply side, too few health professionals provide these essential services.

    • There are multiple successful models of nurse-led long-acting reversible contraception services and postpartum insertion of implants by midwifes nationally and internationally.
    • However, most nurses aren’t able to access Medicare remuneration, which creates additional barriers for this highly skilled workforce to provide these services.

What are the recommendations for reform?

    • The Senate inquiry has recognised these barriers and recommends making contraception universally affordable, and specifically, subsidising copper IUDs.
    • It also recommends adequate remuneration through Medicare for GPs, nurses and midwives to provide long-acting reversible contraception insertion and removal, and collaborative efforts between the government and medical colleges to improve access to workforce training.
    • While the recommendations are welcome, they now need to be turned into actions through adequate funding.