First Life Saved with AI-Discovered Repurposed Medicine for Castleman Disease with Significant Potential Applications to Treat Other Illnesses
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Thursday, July 13, 2023
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PHILADELPHIA, July 13, 2023 /PRNewswire/ -- A patient's life was saved after researchers at the University of Pennsylvania, Castleman Disease Collaborative Network, Medidata, a Dassault Systèmes company, and Every Cure, led by Dr. David Fajgenbaum, utilized AI to uncover a previously unknown use for an existing drug, adalimumab, to treat idiopathic multicentric Castleman disease (iMCD). Every Cure and its partners are developing medical databases and AI algorithms to unlock new uses for existing medicines across all diseases, and the latest scoring identified adalimumab as the most promising treatment for iMCD out of all 3,000 approved drugs.
Key Points:
- Every Cure and its partners are expanding upon this discovery to harness a novel AI algorithm that calculates the potential use of every drug to treat every disease.
- iMCD is a rare and life-threatening disorder that involves hyperactivation of the body's immune system which causes uncontrolled organ dysfunction.
- The only FDA-approved treatment works in a portion of those diagnosed with iMCD, leaving the majority of patients with limited options.
- The algorithm scores every existing drug's potential to treat every known disease based on worldwide knowledge from publications and databases.