Children's Hospital Oakland Research Institute

She Did it!! Ultra Marathon Swimmer Sarah Thomas Completes Swim Across Lake Mead Swimming 47.5 Miles to Make Waves to Fight Cancer for Swim Across America

Retrieved on: 
Tuesday, October 10, 2023
Johns Hopkins University, SAA, UCSF Benioff Children's Hospital, Multimedia, Golden Gate Bridge, Health care, Memorial Sloan Kettering Cancer Center, Hope, Isle, Swimming, Breast cancer, Dostarlimab, The New England Journal of Medicine, Seattle Cancer Care Alliance, Beauty, North Channel (Great Britain and Ireland), GSK plc, Atlantic Ocean, Swim Across America, UCSF, Weill Cornell Medicine, Hoover Dam, Cancer, Sound, Record, Patient, FDA, Movement, Nantucket Cottage Hospital, Immunotherapy, Clinical trial, Volunteering, English, Research, Children's Hospital Oakland Research Institute, Breast Cancer Awareness Month, Water, Hotel, Dentistry, Quarry, Birth control, Lake Mead, Pembrolizumab

LAS VEGAS, Oct. 10, 2023 /PRNewswire-PRWeb/ -- On October 7, 2023, ultra marathon swimmer Sarah Thomas set another world record with a monumental swim that no other swimmer has ever attempted. Sarah completed a 47.5-mile swim (pending ratification) of the entire length of Lake Mead – from the Colorado River to the Hoover Dam. The swim took her 26 hours, 45 minutes and 45 seconds (26:45:45) to complete. Sarah, a breast cancer survivor, took on this swim not just to break another world record, but to help make waves in the fight against cancer and to raise critical funds for cancer research with Swim Across America.

Key Points: 
  • Sarah completed a 47.5-mile swim (pending ratification) of the entire length of Lake Mead – from the Colorado River to the Hoover Dam.
  • I'm a cold water swimmer, so this was a bit warmer than I'm used to, but it ended up being lovely," said Sarah Thomas.
  • I'm so excited to be able to accomplish swimming in Lake Mead, and as a breast cancer survivor, to do it during Breast Cancer Awareness Month, all while raising crucial funds for cancer research with Swim Across America."
  • Sarah has supported Swim Across America since 2018, when the inaugural Swim Across America - Denver swim was held in her home community.

JCR Pharmaceuticals Announces 52-Week Interim Data from its Global Phase I/II Study of JR-171 in Individuals with Mucopolysaccharidosis Type I (MPS I)

Retrieved on: 
Friday, September 29, 2023
Health, General Health, Clinical Trials, Research, Science, Pharmaceutical, Biotechnology, Communication, Central nervous system, DSM-IV codes, Biomarker, Cerebrospinal fluid, MPS, CNS, Trial of the century, BBB, MPS I, ERT, Patient, UCSF, INN, UCSF Benioff Children's Hospital, Children's Hospital Oakland Research Institute, TSE, Hurler, Pharmaceutical industry, MD

JR-171 is a blood brain-barrier (“BBB”)-penetrating form of recombinant α-L-iduronidase that was developed using JCR’s proprietary J-Brain Cargo® technology.

Key Points: 
  • JR-171 is a blood brain-barrier (“BBB”)-penetrating form of recombinant α-L-iduronidase that was developed using JCR’s proprietary J-Brain Cargo® technology.
  • There are no approved therapies that cross the BBB and address the central nervous system (CNS) symptoms for individuals with MPS I.
  • The overall safety data concluded that JR-171 is suitable for the long-term treatment of individuals with MPS I.
  • There is no impact on the consolidated business results for this fiscal year ending on March 31, 2024, related to the matter.

Ultra Marathon Swimmer Sarah Thomas Will Attempt 50-Mile Swim in Lake Mead from Colorado River to the Hoover Dam and Make Waves to Fight Cancer with Swim Across America

Retrieved on: 
Thursday, September 28, 2023
Golden Gate Bridge, Dostarlimab, Volunteering, GSK plc, English, Sound, North Channel (Great Britain and Ireland), Health care, The New England Journal of Medicine, Johns Hopkins University, Clinical trial, Seattle Cancer Care Alliance, Cancer, SAA, Record, Hope, UCSF Benioff Children's Hospital, Research, Multimedia, Immunotherapy, Movement, Beauty, Patient, UCSF, Nantucket Cottage Hospital, Water, Atlantic Ocean, Memorial Sloan Kettering Cancer Center, Isle, Swim Across America, Hoover Dam, Weill Cornell Medicine, FDA, Children's Hospital Oakland Research Institute, Breast cancer, Hotel, Dentistry, Birth control, Dam, Pharmaceutical industry, Lake Mead, Pembrolizumab

LAS VEGAS, Sept. 28, 2023 /PRNewswire-PRWeb/ -- On October 6, 2023, ultra marathon swimmer Sarah Thomas will attempt to set another world record with a monumental swim that no other swimmer has ever attempted. Sarah will set out to complete a 50-mile swim of the entire length of Lake Mead – from the Colorado River to the Hoover Dam. She estimates the swim will take her 30 hours to complete. Sarah, a breast cancer survivor, is undertaking this swim not just to break another world record, but to help make waves in the fight against cancer and to raise critical funds for cancer research with Swim Across America.

Key Points: 
  • Sarah will set out to complete a 50-mile swim of the entire length of Lake Mead – from the Colorado River to the Hoover Dam.
  • Sarah already holds a long list of record-breaking feats and hopes to add the Lake Mead swim to her list.
  • "After my first visit to the Hoover Dam in February 2021, I knew I had to swim across Lake Mead," said Sarah.
  • Sarah's swim across Lake Mead will start in South Cove, where her favorite river, The Colorado, enters the lake.

Swim Across America Launches College Cup and College Ambassador Programs

Retrieved on: 
Tuesday, September 26, 2023
Golden Gate Bridge, Dostarlimab, Johns Hopkins University, Patient, Nantucket Cottage Hospital, Weill Cornell Medicine, Northeastern University, Environment, GSK plc, College Cup, University, Face, Seattle Cancer Care Alliance, UCSF Benioff Children's Hospital, Research, Vasa, North Star College Cup, Athlete, Swimming, UCSF, FDA, Health care, Cancer, SAA, Providence College, Immunotherapy, Outline, Water, Memorial Sloan Kettering Cancer Center, Children's Hospital Oakland Research Institute, The New England Journal of Medicine, Partnership, College, Roger Williams University, Student, Sound, Clinical trial, University of South Florida, Movement, Nursing, Hotel, Swim Across America, Pembrolizumab

CHARLOTTE, N.C., Sept. 26, 2023 /PRNewswire-PRWeb/ -- Swim Across America (SAA) is pleased to announce two new programs aimed at college students and college swim teams who want to make a bigger impact in their community through leadership, fundraising, and friendly competition. The Swim Across America College Cup features 30+ collegiate, club and alumni teams and more than 1,000 participants all united to make waves in the fight against cancer through swimming. The second program is the SAA College Ambassador program where 21 college swimmers and ambassadors have been selected to represent Swim Across America throughout the school year to help raise awareness on the importance of making waves to fight cancer. Both programs are supported through partnerships with College Swimming Coaches Association of America (CSCAA) and Vasa, the fitness training company for swimmers.

Key Points: 
  • New Programs Offer Fun, Fresh, and Exciting Ways for College Students to Make a Bigger Impact With Swim Across America, College Swimming Coaches Association of America, Inc. and Vasa are proud partners of College Cup Competition
    CHARLOTTE, N.C., Sept. 26, 2023 /PRNewswire-PRWeb/ -- Swim Across America (SAA) is pleased to announce two new programs aimed at college students and college swim teams who want to make a bigger impact in their community through leadership, fundraising, and friendly competition.
  • Through December 1, 2023, college or college-affiliated swim teams will compete in the Swim Across America College Cup , a fundraising competition among collegiate teams in the U.S.
  • Swim Across America is also excited to announce another new college initiative, the Swim Across America College Ambassadors program.
  • Earlier this year, Swim Across America invited college students to apply for the Swim Across America College Ambassadors program.

During African American Bone Marrow Awareness Month 10-Year-Old Texas Boy Makes Appeal for More Blood Stem Cell and Marrow Donors

Retrieved on: 
Tuesday, July 12, 2022
MJ, Television, African Americans, Hospital, July, Center, Education, Leukemia, Awareness, Senior, Cheek, Children's Hospital Oakland Research Institute, Cross-matching, Lymphatic system, Degenerative disease, Patient, Enrollment, Texas Children's Hospital, Adult, Cell, Time, Plasma, Center for International Blood and Marrow Transplant Research, Pains, Gift of Life Marrow Registry, Research, National Marrow Donor Program, Medical College of Wisconsin, Cancer, Partnership, FOX, Medical device, Dentistry, Black, Match

MINNEAPOLIS, July 12, 2022 /PRNewswire/ -- July is African American Bone Marrow Awareness Month, and Be The Match is working to raise awareness of a health disparity on the national blood stem cell and marrow registry that affects Black and African American patients in need of life-saving cell therapies. Patients battling blood cancers such as leukemia or blood diseases like sickle cell disease are most likely to find a matching donor in someone who shares their heritage or ethnicity. The odds of finding a match are dependent on a patient's ethnicity, with Black and African American patients least likely to find a matching donor. Black patients find matching donors 29% of the time compared to a 79% chance for white patients.

Key Points: 
  • MINNEAPOLIS, July 12, 2022 /PRNewswire/ --July is African American Bone Marrow Awareness Month, and Be The Match is working to raise awareness of a health disparity on the national blood stem cell and marrow registry that affects Black and African American patients in need of life-saving cell therapies.
  • Black patients find matching donors 29% of the time compared to a 79% chance for white patients.
  • The event combines virtual and in-person events aimed at educating and registering potential donors within the African American community.
  • To learn more about the myths and facts of blood stem cell donation or to join the Be The Match Registry visit http://www.BeTheMatchBLK.org/cheek-week .

Study Shows the Combination of OGM and NGS with Linked-Reads Detects Significantly More Clinically Relevant Variants Resulting in Higher Success Rates for Resolving Previously Unclassified Subjects in Genetic Disease Research

Retrieved on: 
Thursday, October 14, 2021
Data analysis, Genetic testing, WES, WGS, San Francisco, Diagnosis, Genome, UCSF Benioff Children's Hospital, Private Securities Litigation Reform Act, Adoption, Security (finance), Doctor of Philosophy, FGA, NHEJ1, Genomics, Degenerative disease, University of California, San Francisco, Genetics, Lineagen, Disease, Cytogenetics, Karyotype, Deletion, OGM, Autism, GLOBE, Chromosomal translocation, U.S. Securities and Exchange Commission, ASD, NGS, Forward-looking statement, SAN, University, Annual report, Children's Hospital Oakland Research Institute, CEO, Chromosome, UCSF, SVS, Genetic distance, Research, Whole genome sequencing, COVID-19, Medical imaging, Pharmaceutical industry, Risk management

The authors also identified candidate variants in another 60% (18 of 30 cases) for future follow-up.

Key Points: 
  • The authors also identified candidate variants in another 60% (18 of 30 cases) for future follow-up.
  • FGA provides information beyond current assays and results in higher resolution genome maps that can be used for future studies.
  • Fifty percent of the participants in this study had clinically relevant variants hidden in their genomes that WES alone had not uncovered.
  • We believe there is tremendous potential in using OGM together with NGS to understand disease from the very beginning of any study.