AB Science reports a first complete bone marrow response in a relapsed refractory acute myeloid leukemia patient from the very low dose arm of its AB8939 Phase I/II clinical trial (AB18001)
Remarkably, this response was achieved at a very low dose of AB8939, corresponding to the second step of dose increment (out of 13 potential steps) in phase I.
- Remarkably, this response was achieved at a very low dose of AB8939, corresponding to the second step of dose increment (out of 13 potential steps) in phase I.
- At the request of the investigator, AB Science has authorized further treatment cycles of AB8939 to this patient.
- AB8939 treatment of this AML subpopulation is the subject matter of a provisional patent application filed by AB Science.
- Study AB18001 is titled ‘A Phase 1/2 Study to Assess the Safety, Pharmacokinetics, and Efficacy of Daily Intravenous AB8939 in patients with Relapsed/Refractory Acute Myeloid Leukemia’.