PXR

Journal of Pharmaceutical Analysis Articles Provide Novel Insights into Previously Unknown Disease Mechanisms

Retrieved on: 
Tuesday, February 27, 2024
Nerve, Central nervous system, Metabolism, PXR, Alzheimer's disease, Testosterone, PCN, Research, MSI, Diabetic cardiomyopathy, Inflammation, Pathology, Deficit spending, Pregnane X receptor, MALDI, Neurotoxicity, Dysbiosis, JPA, Hippocampus, CYP, Heart failure, DCM, Domestic airport, Phenytoin, Mass spectrometry, PHT, Triglyceride, TMAO, Transplant, Glucocorticoid, Lipid metabolism, Patient, Journal, Glucose, Heart, Mouse, Glycated hemoglobin, Brain

XI'AN, China, Feb. 27, 2024 /PRNewswire/ -- DCM is the leading cause of heart failure in patients with chronic diabetes, with unclear mechanisms and limited treatments. Another mystery is the regulation of cytochrome P450 enzymes (CYPs) in the central nervous system. Moreover, the link between the gut microbiome, microbiota-derived metabolites, and the progression of AD remains unknown. In the December issue of Journal of Pharmaceutical Analysis (JPA), three articles explore the interconnected pathologies of DCM, hippocampal neurotoxicity, and AD, offering a comprehensive insight.

Key Points: 
  • Moreover, the link between the gut microbiome, microbiota-derived metabolites, and the progression of AD remains unknown.
  • In the December issue of Journal of Pharmaceutical Analysis (JPA), three articles explore the interconnected pathologies of DCM, hippocampal neurotoxicity, and AD, offering a comprehensive insight.
  • Their findings, available online on 17 August 2023, were published in Volume 13, Issue 12 of the journal in December 2023.
  • Gut dysbiosis aggravates cognitive deficits, amyloid pathology and lipid metabolism dysregulation in a transgenic mouse model of Alzheimer's disease

PX5 RTOS Simplifies Development of 64-bit Hard Real-Time Applications with Support for IAR Embedded Workbench for Arm

Retrieved on: 
Monday, June 12, 2023
Other Manufacturing, Technology, Security, Software, Manufacturing, Networks, Internet, Hardware, Electronic Design Automation, IOT (Internet of Things), Cortex, Product management, IAR, PXR, AMP, Arm, Memory corruption, Internet of things, API, SMP, Asymmetric, Investment, Asymmetric multiprocessing, Linux, Workload, POSIX, PDV, Symmetric multiprocessing, Safety, Computer data storage

PX5, a global leader in high-performance real-time operating systems and middleware, today announced hard real-time Asymmetric Multiprocessing (AMP) and Symmetric Multiprocessing (SMP) support for the 64-bit Arm architecture integrated with the IAR Embedded Workbench® for Arm® development environment.

Key Points: 
  • PX5, a global leader in high-performance real-time operating systems and middleware, today announced hard real-time Asymmetric Multiprocessing (AMP) and Symmetric Multiprocessing (SMP) support for the 64-bit Arm architecture integrated with the IAR Embedded Workbench® for Arm® development environment.
  • This new support brings unprecedented load balancing and security features to hard real-time applications and complements existing PX5 RTOS Arm support for the 32-bit Cortex-M, Cortex-R, and Cortex-A architectures.
  • “Many applications that demand hard real-time and deterministic processing require capabilities well beyond those of embedded Linux, the most popular operating system for Arm 64-bit architectures,” said William Lamie, CEO, PX5.
  • The industrial-grade PX5 RTOS is an advanced, fifth-generation RTOS designed for the most demanding embedded applications with best-of-class size, performance, safety, and security.

PWR Steer's Innovative PXR Program Includes Pulley with External Reservoir in One Kit

Retrieved on: 
Wednesday, October 19, 2022
OEM, PWR, PGI, Industry, PXR, Program, Multimedia, View, Hydraulic machinery, Video game console

The company has released a new series of Installation Readypower steering pumps - PXR "Pulley with External Reservoir.

Key Points: 
  • The company has released a new series of Installation Readypower steering pumps - PXR "Pulley with External Reservoir.
  • "This new product includes an external reservoir in one kit, enhancing the installation experience and empowering the professional installer and DIYer alike.
  • PXR includes all-new OEM-quality pumps, pulleys, return line fittings, and external reservoirs with cap all in one kit.
  • Unlike most products in the aftermarket, PXR includes all-new OEM-quality pumps, pulleys, return line fittings, and external reservoirs with cap all in one kit.

PXR Web3, the crypto marketing agency on its way to global leadership

Retrieved on: 
Friday, July 22, 2022
Goal, Social media, GLOBE, Industry, Iđoš, CMO, Advertising, Marketing, IDO, PXR, Web3, Communication, ROI, Cryptocurrency, Sales, Public relations

Milan, Italy, July 22, 2022 (GLOBE NEWSWIRE) -- PXR Web3 - the crypto marketing agency for Web3, metaverse and blockchain projects - is on its way to become the leading agency in the market.

Key Points: 
  • Milan, Italy, July 22, 2022 (GLOBE NEWSWIRE) -- PXR Web3 - the crypto marketing agency for Web3, metaverse and blockchain projects - is on its way to become the leading agency in the market.
  • PXR Web3 is the brand of PXR Italy , the Marketing Consulting Firm with global exposure from many years.
  • Among the clients of PXR Web3 there are also investment funds and venture capitals which advise their startups to adopt PXR services to maximize the ROI through marketing.
  • The success of the marketing managed by PXR Web3 is demonstrated by data:
    ICO/IDO average success rate: x4.

Nuclear Receptors and Drug-Drug Interactions: How to Better Understand Potential Toxicity, Upcoming Webinar Hosted by Xtalks

Retrieved on: 
Tuesday, April 12, 2022
Metabolism, Absorption, Pharmacokinetics, ADME, Pharmacology, CAR, CSO, Aryl hydrocarbon receptor, FXR, Industry, Pennsylvania State University, DDI, PXR, Nuclear, Enzyme, Toxicity, Food, NFE2L2, Pregnane X receptor, Pharmaceutical industry

TORONTO, April 12, 2022  /PRNewswire-PRWeb/ -- Drug-drug interactions (DDI) resulting in adverse outcomes cause approximately 3% of all hospitalizations annually in the United States. This costs the health care system over a billion dollars. Fortunately, many aspects of DDI are predictable based on the increasing understanding of the mechanisms of altered absorption, distribution, metabolism and excretion (ADME).

Key Points: 
  • Attendees will also learn how these cell-based screening assays can be used to address species differences in the drug response.
  • TORONTO, April 12, 2022 /PRNewswire-PRWeb/ -- Drug-drug interactions (DDI) resulting in adverse outcomes cause approximately 3% of all hospitalizations annually in the United States.
  • Register for this webinar to learn about various drug screening assays that are available for identifying potential DDI in vitro.
  • For more information, or to register for this event, visit Nuclear Receptors and Drug-Drug Interactions: How to Better Understand Potential Toxicity.