Quorum sensing

NEW INVESTIGATORS JOIN STOWERS INSTITUTE FOR MEDICAL RESEARCH

Retrieved on: 
Wednesday, May 3, 2023

KANSAS CITY, Mo., May 3, 2023 /PRNewswire/ -- The Stowers Institute for Medical Research announced the hiring of three principal investigators to further expand its team of scientists who seek to answer life's biggest mysteries through foundational research. Siva Sankari, Ph.D., from Massachusetts Institute for Technology, Neşet Özel, Ph.D., from New York University, and Ameya Mashruwala, Ph.D., from Princeton University, will join the Institute's current team of 17 principal investigators and staff of 500. The addition of these scientists will result in a total of 20 research labs at the Stowers Institute.

Key Points: 
  • KANSAS CITY, Mo., May 3, 2023 /PRNewswire/ -- The Stowers Institute for Medical Research announced the hiring of three principal investigators to further expand its team of scientists who seek to answer life's biggest mysteries through foundational research.
  • The addition of these scientists will result in a total of 20 research labs at the Stowers Institute.
  • "Recruitment of these three individuals solidifies the Stowers Institute and Kansas City as a life sciences powerhouse in the Midwest.
  • Sankari added, "The highly interdisciplinary, collaborative structure of the Stowers Institute is an ideal place to answer my complex research questions.

Humans weren't the first engineers, doctors and farmers – bacteria, plants and animals have lots to teach us

Retrieved on: 
Wednesday, April 19, 2023

Yet we often ignore the achievements of species that preceded us by billions of years.

Key Points: 
  • Yet we often ignore the achievements of species that preceded us by billions of years.
  • Bacteria, plants, fungi, insects, birds, whales and other species demonstrate language, engineering, science, medicine, agriculture and more.

Speaking nature’s language

    • Now, scientists from around the world are collaborating as part of the Cetacean Translation Initiative to use powerful AI algorithms and decode the language of sperm whales.
    • Plants communicate with each other using hormones such as jasmonate, which redirects resources from growth to repairing damage.
    • Meanwhile, bacteria have been “talking” to each other for billions of years by exchanging chemical messages via hormone-like molecules called autoinducers.
    • Studies into premature babies have shown the relationship between gut bacteria and human cells are crucial for cognitive development.

Skilled engineers

    • It is a permanent building site where bacteria, insects and humans alike create cities.
    • The engineering skills of honeybees are so sophisticated that a honeybee expert and a group of engineers used an algorithm inspired by honeybees to resolve internet traffic problems.
    • Bacteria are skilled engineers too.
    • Indeed, the entire planet was turned into a kind of bacterial internet three billion years ago.

Doctors and surgeons

    • Viruses invade bacteria and hijack their cellular machinery to make copies of themselves – a process which kills the bacteria.
    • Bacterial bodies produce enzymes that attack and kill virus DNA, a technique known as Crspr.
    • But ants from the species Megaponera analis, found in sub-Saharan Africa, are talented surgeons.
    • These ant surgeons were so effective that patients were spotted on the battlefield the next day.

Successful farmers

    • In turn, ambrosia beetles transport fungus spores in a pouch-like structure in their gut to tunnels bored into trees.
    • So, these tiny beings were all farmers millions of years before humans had even thought of it.
    • In so doing, this newly discovered wisdom could help us resolve the environmental crisis caused by our civilisation.

Researchers Discover Previously Unknown Role of BioAegis’ Therapeutic Gelsolin as Key Signaling Protein Vital for Regulating Immune Cell Inflammatory Response

Retrieved on: 
Tuesday, September 28, 2021

NORTH BRUNSWICK, New Jersey, Sept. 28, 2021 (GLOBE NEWSWIRE) -- BioAegis Therapeutics Inc., a clinical stage, private company developing therapies for infectious, inflammatory, and degenerative diseases based on a portfolio built around gelsolin technology, announced that a previously unknown role of gelsolin in a signaling system in macrophages was published in the Journal of Immunology.

Key Points: 
  • The paper, Quorum Sensing by Gelsolin Regulates Programmed Cell Death 4 Expression and a Density-Dependent Phenotype in Macrophages , was recently published in the Journal of Immunology.
  • The study shows that plasma gelsolin (pGSN) controls this process by regulating the expression of a protein known as Programmed Cell Death 4 (PCD4).
  • Gelsolin, a naturally occurring human protein that is abundant in healthy individuals, is a key component of the bodys innate immune system.
  • BioAegis will also have US biologics exclusivity and has recently filed new IP in areas of unmet need.

Quorum Sensing, 2019 - Food Packaging, Drug Delivery & Marine Biofilm - ResearchAndMarkets.com

Retrieved on: 
Wednesday, November 27, 2019

Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms.

Key Points: 
  • Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms.
  • It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application.
  • This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm.
  • Marine organisms, in particular sponges, plants and marine microorganisms are objects of her studies.