Kanazawa University research: Biochemical tails tell a story
Of particular importance in these processes are the end structures, or tails, of the histones.
- Of particular importance in these processes are the end structures, or tails, of the histones.
- Detailed studies, and especially visualizations, of nucleosome dynamics are crucial for better understanding the role of histone tails.
- Mikihiro Shibata from Kanazawa University and colleagues have now succeeded in making video recordings of tail-less nucleosomes, showing that the absence of histone tails significantly increases a nucleosome's dynamic activity.
- Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have in recent years developed HS-AFM further, so that it can be applied to study biochemical molecules and biomolecular processes in real-time.