Histone

Kanazawa University research: Biochemical tails tell a story

Retrieved on: 
Wednesday, April 24, 2024
Protein, Histone, Map, X-ray crystallography, Animal, AFM, Motion, Plant, H3, Nano Letters, Lens, DNA, Kanazawa University, Nucleosome, Gene expression, H4, H2B, Microscope

Of particular importance in these processes are the end structures, or tails, of the histones.

Key Points: 
  • Of particular importance in these processes are the end structures, or tails, of the histones.
  • Detailed studies, and especially visualizations, of nucleosome dynamics are crucial for better understanding the role of histone tails.
  • Mikihiro Shibata from Kanazawa University and colleagues have now succeeded in making video recordings of tail-less nucleosomes, showing that the absence of histone tails significantly increases a nucleosome's dynamic activity.
  • Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have in recent years developed HS-AFM further, so that it can be applied to study biochemical molecules and biomolecular processes in real-time.

Kanazawa University research: Biochemical tails tell a story

Retrieved on: 
Wednesday, April 24, 2024
Protein, Histone, Map, X-ray crystallography, Animal, AFM, Motion, Plant, H3, Nano Letters, Lens, DNA, Kanazawa University, Nucleosome, Gene expression, H4, H2B, Microscope

Of particular importance in these processes are the end structures, or tails, of the histones.

Key Points: 
  • Of particular importance in these processes are the end structures, or tails, of the histones.
  • Detailed studies, and especially visualizations, of nucleosome dynamics are crucial for better understanding the role of histone tails.
  • Mikihiro Shibata from Kanazawa University and colleagues have now succeeded in making video recordings of tail-less nucleosomes, showing that the absence of histone tails significantly increases a nucleosome's dynamic activity.
  • Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have in recent years developed HS-AFM further, so that it can be applied to study biochemical molecules and biomolecular processes in real-time.

Sepsis Drug Pipeline Research Report 2024: Insights from 30 Companies and 35 Pipeline Drugs - ResearchAndMarkets.com

Retrieved on: 
Tuesday, February 27, 2024
Pharmaceutical, Health, Clinical Trials, Therapy, Acquisition, Blood pressure, HBV, HCV, Hepatitis B virus, Heparin, CRISPR, Infection, Escherichia coli, Melanoma, News, Cancer, Liver cancer, Discovery, Cell, Vaccine, Intensive care medicine, Adrenomedullin, ADM, COVID, Fungal infection, Patient, Protein, Clinical trial, Survival, Endothelium, NDA, Histone, Thymosin

This report provides comprehensive insights about 30+ companies and 35+ pipeline drugs in Sepsis pipeline landscape.

Key Points: 
  • This report provides comprehensive insights about 30+ companies and 35+ pipeline drugs in Sepsis pipeline landscape.
  • A detailed picture of the Sepsis pipeline landscape is provided which includes the disease overview and Sepsis treatment guidelines.
  • This segment of the Sepsis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery.
  • The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Sepsis drugs.

Kanazawa University research: Chromatin Accessibility: A new avenue for gene editing

Retrieved on: 
Friday, February 16, 2024
Nucleosome, ATAC, Kanazawa University, CRISPR, Gene editing, Stem cell, B cell, TFDP1, Genome, Digital selective calling, Protein, Gene, Histone, DNA, Running, Chromatin, Vaccine

KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.

Key Points: 
  • KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.
  • This phenomenon known as 'chromatin accessibility' involves a privileged set of protein molecules, many of which are still unknown.
  • Now, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, led by Yusuke Miyanari, have used advanced genetic screening methods to unravel chromatin accessibility and its pathways.
  • In this study the genes identified by CRISPR screening were subjected to ATAC-see to confirm their involvement with chromatin accessibility.

Kanazawa University research: Chromatin Accessibility: A new avenue for gene editing

Retrieved on: 
Friday, February 16, 2024
Nucleosome, ATAC, Kanazawa University, CRISPR, Gene editing, Stem cell, B cell, TFDP1, Genome, Digital selective calling, Protein, Gene, Histone, DNA, Running, Chromatin, Vaccine

KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.

Key Points: 
  • KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.
  • This phenomenon known as 'chromatin accessibility' involves a privileged set of protein molecules, many of which are still unknown.
  • Now, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, led by Yusuke Miyanari, have used advanced genetic screening methods to unravel chromatin accessibility and its pathways.
  • In this study the genes identified by CRISPR screening were subjected to ATAC-see to confirm their involvement with chromatin accessibility.

Groundbreaking Results Using Canady Helios™ Cold Plasma Treatment Published in MDPI Journal “Cancers”

Retrieved on: 
Wednesday, August 2, 2023
Research, Technology, Medical Devices, Surgery, Health Technology, Biotechnology, Robotics, Health, Science, Oncology, Canady, Cell death, RNS, Histone, Survival, Clinical trial, Immunotherapy, CHCP, Irreversible electroporation, Plasma, ROS, Cancer, LRR, Patient, Sheba Medical Center, Reactive oxygen species, Apoptosis, Education minister, Cell division, FACS, Neoplasm, Rush University Medical Center, Recurrence, FDA, Reactive nitrogen species, Messenger, Pharmaceutical industry

It is estimated that 65% of solid tumor resections result in residual microscopic tumor cells at the surgical margin, which contributes to LRR and poor survival rates.

Key Points: 
  • It is estimated that 65% of solid tumor resections result in residual microscopic tumor cells at the surgical margin, which contributes to LRR and poor survival rates.
  • The recent trial reveals that treating the surgical margin following a tumorectomy significantly reduced local recurrence and increased overall survival.
  • CHCP opens a new and promising treatment for addressing the challenges of eradicating microscopic residual cancer cells following surgical tumor resection.
  • Jerome Canady, M.D., FACS, CEO stated, “We are very pleased to have our results published in the peer reviewed journal 'Cancers'.

HiStone's LUNA X HK568/HK568U: The Game-Changing POS Solution Redefining Retail and Hospitality Experiences

Retrieved on: 
Wednesday, June 28, 2023
Rotation, POS, Business, Central processing unit, Sale, Histone, LATAM, Mobile phone, Online shopping

QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U. This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.

Key Points: 
  • HiStone reveals LUNA X HK568/HK568U, an all-in-one point-of-sale (POS) model revolutionizing the retail and hospitality industries
    QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U.
  • This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.
  • This enhanced processing capability empowers retailers and hospitality providers to handle complex operations efficiently, ensuring frictionless payment services for their customers.
  • With the launch of the HK568/HK568U, HiStone once again demonstrates its commitment to driving digital transformation and supporting businesses in the retail and hospitality sectors.

HiStone's LUNA X HK568/HK568U: The Game-Changing POS Solution Redefining Retail and Hospitality Experiences

Retrieved on: 
Wednesday, June 28, 2023
Rotation, POS, Business, Central processing unit, Sale, Histone, Mobile phone, Online shopping

QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U. This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.

Key Points: 
  • HiStone reveals LUNA X HK568/HK568U, an all-in-one point-of-sale (POS) model revolutionizing the retail and hospitality industries
    QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U.
  • This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.
  • This enhanced processing capability empowers retailers and hospitality providers to handle complex operations efficiently, ensuring frictionless payment services for their customers.
  • With the launch of the HK568/HK568U, HiStone once again demonstrates its commitment to driving digital transformation and supporting businesses in the retail and hospitality sectors.

HiStone's LUNA X HK568/HK568U: The Game-Changing POS Solution Redefining Retail and Hospitality Experiences

Retrieved on: 
Wednesday, June 28, 2023
Rotation, POS, Central processing unit, Sale, Histone, Mobile phone, Online shopping

QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U. This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.

Key Points: 
  • HiStone reveals LUNA X HK568/HK568U, an all-in-one point-of-sale (POS) model revolutionizing the retail and hospitality industries
    QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U.
  • This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.
  • This enhanced processing capability empowers retailers and hospitality providers to handle complex operations efficiently, ensuring frictionless payment services for their customers.
  • With the launch of the HK568/HK568U, HiStone once again demonstrates its commitment to driving digital transformation and supporting businesses in the retail and hospitality sectors.

HiStone's LUNA X HK568/HK568U: The Game-Changing POS Solution Redefining Retail and Hospitality Experiences

Retrieved on: 
Wednesday, June 28, 2023
Rotation, POS, Business, Central processing unit, Sale, Histone, Mobile phone, Online shopping

QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U. This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.

Key Points: 
  • HiStone reveals LUNA X HK568/HK568U, an all-in-one point-of-sale (POS) model revolutionizing the retail and hospitality industries
    QINGDAO, China, June 28, 2023 /PRNewswire/ -- HiStone, a leading provider of innovative POS and Self-Checkout hardware solutions, announces the release of its latest addition to the LUNA X model range, the HK568/HK568U.
  • This all-in-one POS model sets new standards in performance, flexibility, and user experience, solidifying HiStone's position as a reliable and premium-quality technology vendor in the industry.
  • This enhanced processing capability empowers retailers and hospitality providers to handle complex operations efficiently, ensuring frictionless payment services for their customers.
  • With the launch of the HK568/HK568U, HiStone once again demonstrates its commitment to driving digital transformation and supporting businesses in the retail and hospitality sectors.