Dizziness

The American Dream: Doctors Unite to Educate About Proactive Health on "The World Wellness Show"

Retrieved on: 
Thursday, March 14, 2024

GAINESVILLE, Fla., March 14, 2024 (GLOBE NEWSWIRE) -- The World Wellness Show expands collaborative movement towards proactive health to 137 countries with the help of top wellness experts.

Key Points: 
  • GAINESVILLE, Fla., March 14, 2024 (GLOBE NEWSWIRE) -- The World Wellness Show expands collaborative movement towards proactive health to 137 countries with the help of top wellness experts.
  • Doctors wanting to share "their messages" globally and create personalized content for their clinic's social media and websites can schedule their interview now at: www.TheWorldWellnessShow.com .
  • Trish Gleason, Host of the World Wellness Show, shared: “Together we can educate the world and spark a shift in wellcare from treatment to prevention.
  • Our goal is to spark a paradigm shift to how we perceive and prioritize health and move away from reactive treatments and towards proactive wellness practices.

 Bristol Myers Squibb Presents New Pooled Interim Long-Term Safety and Metabolic Outcomes Data from the EMERGENT Program Evaluating KarXT in Schizophrenia at the 2024 Annual Congress of the Schizophrenia International Research Society

Retrieved on: 
Saturday, April 6, 2024

Bristol Myers Squibb (NYSE: BMY) today announced interim long-term safety, tolerability and metabolic outcomes data from its Phase 3 EMERGENT program evaluating KarXT (xanomeline-trospium) in adults with schizophrenia.

Key Points: 
  • Bristol Myers Squibb (NYSE: BMY) today announced interim long-term safety, tolerability and metabolic outcomes data from its Phase 3 EMERGENT program evaluating KarXT (xanomeline-trospium) in adults with schizophrenia.
  • “These long-term safety results and metabolic outcomes from the EMERGENT program are extremely encouraging, allowing us to further understand the tolerability profile of KarXT in people living with schizophrenia,” said Roland Chen , MD, senior vice president and head, Immunology, Cardiovascular and Neuroscience development, Bristol Myers Squibb.
  • In the pooled analysis, KarXT demonstrated a favorable impact on weight and long-term metabolic profile where most patients experienced stability or improvements on key metabolic parameters over 52 weeks of treatment.
  • In the long-term studies, KarXT was generally well-tolerated across 52 weeks of treatment, with a side effect profile consistent with prior trials of KarXT in schizophrenia.

Astria Therapeutics Announces Positive Initial Proof-of-Concept Results from the ALPHA-STAR Phase 1b/2 Trial of STAR-0215 for HAE

Retrieved on: 
Monday, March 25, 2024

Based on the positive results, Astria plans to advance STAR-0215 to Phase 3 development with trial initiation expected in Q1 2025 and top-line results expected by year-end 2026.

Key Points: 
  • Based on the positive results, Astria plans to advance STAR-0215 to Phase 3 development with trial initiation expected in Q1 2025 and top-line results expected by year-end 2026.
  • Initial safety and efficacy data from Q3M and Q6M dosing in the ALPHA-SOLAR trial are expected mid-2025.
  • Pending regulatory feedback, the Company expects to start a pivotal Q3M Phase 3 trial in Q1 2025, with top-line results expected by year-end 2026.
  • Interested parties may join the webcast via the Investors section of the Astria website, www.astriatx.com or with following the link https://lifescievents.com/event/astriatx/ .

Alnylam Launches Hereditary ATTR (hATTR) Amyloidosis Campaign to Help Shorten Time to Diagnosis for Inherited and Rapidly Progressive Disease

Retrieved on: 
Wednesday, March 13, 2024

“Family history is considered one of the most important risk factors for health problems.

Key Points: 
  • “Family history is considered one of the most important risk factors for health problems.
  • “It took seeing nine doctors over seven years for me to finally receive a diagnosis of hATTR amyloidosis,” said Christine, a Family Health History Road Trip participant who is living with hATTR amyloidosis.
  • If I had, I could have potentially been diagnosed and started on a disease management plan much earlier.”
    With an inherited disease like hATTR amyloidosis that progresses rapidly, early diagnosis is crucial.
  • A genetic test can determine whether a person carries one of the more than 120 variants in the TTR gene associated with hATTR amyloidosis.

Merck Announces Plans to Conduct Clinical Trials of a Novel Investigational Multi-Valent Human Papillomavirus (HPV) Vaccine and Single-Dose Regimen for GARDASIL®9

Retrieved on: 
Wednesday, March 13, 2024

Separately, the company also plans to conduct clinical trials in both females and males to evaluate the efficacy and safety of a single-dose regimen of GARDASIL®9 (Human Papillomavirus 9-valent, recombinant), compared to the approved three-dose regimen.

Key Points: 
  • Separately, the company also plans to conduct clinical trials in both females and males to evaluate the efficacy and safety of a single-dose regimen of GARDASIL®9 (Human Papillomavirus 9-valent, recombinant), compared to the approved three-dose regimen.
  • Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.
  • The latest addition to the pipeline employs the company’s proprietary virus-like particle (VLP) technology to incorporate additional VLPs for expanded HPV type coverage.
  • These randomized, double-blind, multi-year clinical trials will examine the short and long-term efficacy and immunogenicity of a single-dose of GARDASIL 9 versus the currently approved three-dose regimen.

FDA Approves New Antibiotic for Three Different Uses

Retrieved on: 
Wednesday, April 3, 2024

"The FDA will continue our important work in this area as part of our efforts to protect the public health."

Key Points: 
  • "The FDA will continue our important work in this area as part of our efforts to protect the public health."
  • Zevtera's efficacy in treating SAB was evaluated in a randomized, controlled, double-blind, multinational, multicenter trial .
  • In the trial, researchers randomly assigned 390 subjects to receive Zevtera (192 subjects) or daptomycin plus optional aztreonam [the comparator] (198 subjects).
  • A total of 69.8% of subjects who received Zevtera achieved overall success compared to 68.7% of subjects who received the comparator.

Athletico Physical Therapy Opens in Grand Blanc, Michigan

Retrieved on: 
Thursday, March 28, 2024

GRAND BLANC, Mich., March 28, 2024 /PRNewswire/ -- Athletico Physical Therapy has opened a new location in Grand Blanc, Michigan, located across from Kroger and next to Starbucks on S. Saginaw Rd. This location offers convenient hours, including early morning, late evening and Saturday appointments, and does not require a referral or prescription to start treatment. To learn more, or to schedule a free assessment, visit www.athletico.com/GrandBlanc.

Key Points: 
  • GRAND BLANC, Mich., March 28, 2024 /PRNewswire/ -- Athletico Physical Therapy has opened a new location in Grand Blanc, Michigan, located across from Kroger and next to Starbucks on S. Saginaw Rd.
  • "I'm looking forward to providing quality physical therapy services to patients in the wonderful community of Grand Blanc," said Brad Bond, PT, DPT, Clinic Manager of Athletico Grand Blanc.
  • "Physical therapy has many benefits for individuals experiencing pain, decreased range of motion, strength or balance issues, and anything that impairs the quality and function of their life.
  • Services available at Athletico Grand Blanc include:
    Physical therapy – Our physical therapists treat you to reduce pain, improve or restore mobility, and to help you remain at your optimal health without further risk of injury.

Advisory - Only use authorized nicotine pouches as directed, and do not use unauthorized nicotine pouches

Retrieved on: 
Wednesday, March 20, 2024

Consuming multiple nicotine products at the same time, including authorized nicotine replacement therapy products, or varenicline (a prescription smoking cessation drug), may increase the adverse effects of nicotine.

Key Points: 
  • Consuming multiple nicotine products at the same time, including authorized nicotine replacement therapy products, or varenicline (a prescription smoking cessation drug), may increase the adverse effects of nicotine.
  • Use authorized nicotine pouches only as directed:
    To date, Health Canada has authorized only one nicotine pouch , containing 4 mg of nicotine per dose.
  • Nicotine replacement therapies, including nicotine pouches, are not authorized for recreational use or for use by nonsmokers and people under 18 years old.
  • There are no authorized nicotine pouches in Canada that contain more than 4 mg of nicotine per dose.

Huawei Named a Leader in the 2024 Gartner® Magic Quadrant™ for Enterprise Wired and Wireless LAN Infrastructure, with Highest 3 in the "Ability to Execute"

Retrieved on: 
Monday, March 11, 2024

SHENZHEN, China, March 11, 2024 /PRNewswire/ -- Huawei announced that it was named a Leader in the 2024 Gartner® Magic Quadrant™ for Enterprise Wired and Wireless LAN Infrastructure, the only non-North American vendor positioned in the Leaders Quadrant.

Key Points: 
  • SHENZHEN, China, March 11, 2024 /PRNewswire/ -- Huawei announced that it was named a Leader in the 2024 Gartner® Magic Quadrant™ for Enterprise Wired and Wireless LAN Infrastructure, the only non-North American vendor positioned in the Leaders Quadrant.
  • Nowadays, it is widely recognized that 2024 is the first year for large-scale deployment of Wi-Fi 7.
  • As a leader in Wi-Fi 7, Huawei will continue to launch 13 all-scenario Wi-Fi 7 APs in 2024, helping enterprises to build leading digital infrastructure.
  • Looking ahead, Huawei will continue to delve into technical research and product innovation regarding enterprise wired and wireless LAN infrastructure.

Why cocaine is considered performance-enhancing for athletes, and why it matters when the athlete took it

Retrieved on: 
Wednesday, April 3, 2024

Last year a Melbourne Demons player, Joel Smith, and two Sydney Swans AFLW players were caught with cocaine.

Key Points: 
  • Last year a Melbourne Demons player, Joel Smith, and two Sydney Swans AFLW players were caught with cocaine.
  • So how is cocaine considered performance enhancing, and why does it matter when they took it?

What is cocaine and is it performance enhancing?

  • Once consumed, cocaine increases the level of a chemical in the brain called dopamine – a messenger molecular that is associated with pleasure and reward.
  • A surge in dopamine is responsible for feelings of euphoria, heightened energy, and alertness, which makes cocaine highly sought-after for recreational purposes.
  • When used during sport, cocaine is considered to have performance enhancing effects and is prohibited under the World Anti-Doping Code and listed under the Substances of Abuse Category.

Recreational (out of competition) vs performancing-enhancing (in-competition) use

  • As a result, instead of a ban from competing, the court gave them 12-month conditional release orders, with no convictions recorded.
  • Under the AFL’s anti-doping code, a finding of using cocaine for performance enhancement could come with a four-year ban.
  • If he was found to have used it for only recreational purposes, not on game day, the ban would instead just be one or three months.

Can urine testing determine when someone took cocaine?

  • Intact cocaine can remain detectable in urine for periods up to 15 days, and BZE can be detectable up to 25 days.
  • To determine the date of cocaine use, the concentration of intact drug in the athlete’s urine, and possibly the BZE concentration, need to be considered.
  • But there are fundamental flaws in making these comparisons to determine when an athlete took cocaine.

Why is cocaine still considered performance-enhancing?


While it’s unlikely an athlete can genuinely get an athletic edge on their rivals by taking cocaine, it is still on Sports Integrity Australia’s Prohibited List because “all prohibited substances are added to the Prohibited List because they meet two of the three following criteria”:
Athletes really are risking a lot for minimal (if any) athletic reward when they take cocaine – not just the health risks, but the possibility of getting caught with a substance that is extremely unlikely to improve their on-field performances.
Nial Wheate has previously appeared as an expert witness for an athlete accused by Sport Integrity Australia of in-competition cocaine use. Shoohb Alassadi does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.