University of Colorado Colorado Springs

XORTX Sponsored Study Presented at the American Society of Nephrology – Kidney Week 2023

Retrieved on: 
Thursday, November 2, 2023
Uric acid, Session, University of Colorado Colorado Springs, ADPKD, Xanthine oxidase, Polycystic kidney disease, Effect, Cytokine, Research, Society, American Society of Nephrology, Acute kidney injury, PKD, ASN, Hyperuricemia, Kidney disease, University, Diet, Nephrology, Therapy, Patient, Oxipurinol, Pharmaceutical industry, Phosphorus, Prognosis

CALGARY, Alberta, Nov. 02, 2023 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. ("XORTX" or the “Company”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat progressive kidney disease, is pleased to announce the presentation of new research findings at the American Society of Nephrology meeting being held November 3, 2023 in Philadelphia. The abstract entitled "The Effect of Lowering Uric Acid with a Xanthine Oxidase Inhibitor on PKD in Mice” was reviewed by the ASN review panel for scientific merit and novel discoveries. The studies were conducted at the University of Colorado in the independent laboratory of Dr. Charles Edelstein and were sponsored by XORTX. The studies will be presented at Kidney Week during the Session Title: Genetic Diseases: Cystic - Therapeutic Investigations and Prognosis, November 2, 2023.

Key Points: 
  • The studies were conducted at the University of Colorado in the independent laboratory of Dr. Charles Edelstein and were sponsored by XORTX.
  • The studies will be presented at Kidney Week during the Session Title: Genetic Diseases: Cystic - Therapeutic Investigations and Prognosis, November 2, 2023.
  • This poster reports amalgamated results of studies in either rat and mouse models of polycystic kidney disease (“PKD”) challenged with low to moderate circulating uric acid.
  • The effect of increased uric acid on cyst growth – kidney size - and kidney function, as well as inflammatory markers was measured.

XORTX Sponsored Study Selected for Presentation at the American Society of Nephrology – Kidney Week 2023

Retrieved on: 
Thursday, September 28, 2023
Session, University of Colorado Colorado Springs, University, Xanthine oxidase, Effect, American Society of Nephrology, PKD, Research, ASN, Uric acid, Polycystic kidney disease, Patent, ADPKD, Prognosis, Therapy, Kidney, Society, Kidney disease, Pharmaceutical industry

The abstract outlines study results from a mouse model of polycystic kidney disease challenged with low to moderate circulating uric acid.

Key Points: 
  • The abstract outlines study results from a mouse model of polycystic kidney disease challenged with low to moderate circulating uric acid.
  • The study also identifies a novel inflammatory profile as a possible mechanism of injury inducing an increased cyst index and kidney enlargement.
  • XORTX will provide further details of the study at the time of the presentation during the first week of November at the ASN meeting scheduled for November 2, 2023.
  • XORTX granted patents and additional patent applications supporting the XRx-008 program are wholly owned by XORTX.”

BioLoomics Raises $8.7 Million Seed Round to Develop Target Degrading Antibodies

Retrieved on: 
Tuesday, September 19, 2023
Research, Technology, Infectious Diseases, Stem Cells, Biotechnology, Pharmaceutical, Robotics, Health, Science, Other Science, Cell biology, University of Colorado Colorado Springs, University, Therapy, CSO, RTA, Cancer, Eric Schmidt, Innovation, Antibody, DARPA, Li Ka-shing, Machine learning, Engineering, Cell engineering, SVP, Independent Board for Presbyterian Foreign Missions, Pfizer, Disease, Fine chemical, Vaccine

BioLoomics , the company pioneering directed evolution of target degrading antibodies using human cells, today announced it has raised $8.7 million in seed financing to advance its proprietary platform technology and antibody degrader programs.

Key Points: 
  • BioLoomics , the company pioneering directed evolution of target degrading antibodies using human cells, today announced it has raised $8.7 million in seed financing to advance its proprietary platform technology and antibody degrader programs.
  • He founded BioLoomics to apply principles from the RTA project to overcome market-wide throughput limitations for activity-based discovery of antibodies.
  • “Our mission is to make safer, more effective cancer therapeutics by hijacking how human proteins move antibodies around the cell,” said Dr. Douglas Chapnick, founder and CEO of BioLoomics.
  • With this new capital, BioLoomics will develop pre-clinical assets and form strategic partnerships with large pharma companies.

CiviCO Announces 2023-2024 Colorado Governors Fellows

Retrieved on: 
Monday, August 14, 2023
University of Colorado Colorado Springs, Partnership, University, Public policy, Museo Civico, Work, Fort Collins, Colorado, Management, Private investigator, Road

DENVER, Aug. 14, 2023 /PRNewswire/ -- CiviCO, a nonprofit that cultivates civic-minded leaders, announced 30 Colorado business executives and community leaders as 2023-24 Colorado Governors Fellows. The program prepares private and nonprofit sector leaders opportunities to deepen their understanding of Colorado state government and public policy issues by fostering meaningful connections with former and current administration officials.

Key Points: 
  • DENVER, Aug. 14, 2023 /PRNewswire/ -- CiviCO , a nonprofit that cultivates civic-minded leaders, announced 30 Colorado business executives and community leaders as 2023-24 Colorado Governors Fellows.
  • "I am thrilled to welcome the newest cohort of Governors Fellows through the continued partnership between CiviCO and the Colorado Governor's Office.
  • These fellows will gain valuable experience and go on to help ensure Colorado is the best place to live, work and run a business," said Governor Jared Polis.
  • Josh Beard - Fort Collins, Liquor Store Services, Inc. (DBA Bullfrog Wine/Spirits, Mulberry Max Wine/Spirits)
    Alana Lipscomb - Colorado Springs, Kingdom Builders Family Life Center
    Stephanie Einfeld - Steamboat Springs, Northwest Colorado Health
    Kimberly Gold - Colorado Springs, The Gold Standard
    Kathryn V Harris - Denver, ActivateWork
    Malikah Marrus - Colorado Springs, University of Colorado - Colorado Springs
    Trevor Nolan - Colorado Springs, Summit Advanced Program Consulting
    Brandon Stam - Grand Junction, Downtown Grand Junction Partnership
    David Thurow - Grand Junction, Prosono
    "The program creates a space for leaders to grow their civic engagement and multi-sector leadership," said Ryan Heckman, chairman of CiviCO.

Zillow's top markets for college grads offer a balance of opportunity and affordability

Retrieved on: 
Wednesday, May 24, 2023
LBGTQ, University of Colorado Colorado Springs, 3D@Home Consortium, Quality of life, Recreation, Housing, Zillow, ZIP, Research, Gonzaga University, Nursing, Renting, Lease

SEATTLE, May 24, 2023 /PRNewswire/ -- Colorado Springs, Colorado, has been named Zillow's top market for college grads in 2023, highlighting how, this year, markets with a smaller population, relatively affordable rents and lots of career prospects contribute to a high quality of life for individuals beginning a new phase in their lives.

Key Points: 
  • These vibrant regions offer abundant job opportunities along with rents that are more affordable than their larger metro counterparts Denver and Seattle.
  • College graduates flock to these areas, seeking an excellent quality of life, outdoor recreation and economic prospects at a reasonable cost.
  • Among the top metros, Phoenix and Portland stand out as the largest markets by population size.
  • Peak rental season is in full swing, and new college grads looking to sign a lease only add to the competition for rentals.

University of Colorado Colorado Springs Launches New Equitable Access Program with Akademos Partnership

Retrieved on: 
Thursday, April 6, 2023
Colorado Springs, Colorado, Learning, Academus, Partnership, University of Colorado Colorado Springs, University, Education, UCCS, EVP, Student, Textbook, Access, OER, Community Access Program, Book, Software, Tutoring

COLORADO SPRINGS, Colo., April 6, 2023 /PRNewswire/ -- The University of Colorado Colorado Springs today announced a partnership with online bookstore technology company Akademos to help launch their new Textbook Affordability & Access Program (TAAP), to reduce the cost of attendance and increase the accessibility of course materials for its 12,000+ students.

Key Points: 
  • COLORADO SPRINGS, Colo., April 6, 2023 /PRNewswire/ -- The University of Colorado Colorado Springs today announced a partnership with online bookstore technology company Akademos to help launch their new Textbook Affordability & Access Program (TAAP), to reduce the cost of attendance and increase the accessibility of course materials for its 12,000+ students.
  • "Reducing the out-of-pocket cost of books by over 30% will help ensure all of our students have access to the materials they need to succeed."
  • "We are proud to partner with the University of Colorado Colorado Springs as they continue to innovate and fuel success for many generations of UCCS graduates to come."
  • More information regarding the UCCS Textbook Affordability and Access Program can be found at: uccs.edu/TAAP

XORTX Announces New Proof of Concept Data in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Retrieved on: 
Thursday, December 8, 2022
Kidney disease, Uric acid, XOI, Kidney failure, Heart, Oxipurinol, TKV, XO, Polycystic kidney disease, Time-invariant system, Fibrosis, Society, University of Colorado Colorado Springs, Nephrology, Therapy, Xanthine oxidase, Creatinine, University, American Society of Nephrology, Pharmaceutical industry, Dietary supplement, Hyperuricemia, ADPKD

If Xanthine oxidase (XO) is expressed in the mouse RC/RC model of polycystic kidney disease (“PKD”), a model for human ADPKD.

Key Points: 
  • If Xanthine oxidase (XO) is expressed in the mouse RC/RC model of polycystic kidney disease (“PKD”), a model for human ADPKD.
  • How increased circulating uric acid concentrations in the cardiovascular system affect kidney weight, heart, inflammatory status and fibrosis.
  • How inhibiting of XO by XORTX’s proprietary XRx-008 formulation of oxypurinol, XORLOTM, attenuates total kidney volume, cyst genesis and cyst growth rate.
  • Pkd1RC/RC mouse develops a slowly progressing polycystic kidney disease with embryonic cyst initiation, present cystic lesions in the liver and elongated primary cilia in collecting ducts.

PathologyWatch Welcomes Joseph Willman, MD, to Digital Dermatopathology Practice

Retrieved on: 
Thursday, November 17, 2022
Health, Dermatology, Workflow, Pathology, Marie Cassidy, MD, University, Clinical professor, Internal medicine, Patient, SALT, University of Colorado Colorado Springs, Hospital, EMR, Laboratory, Medical device, Medical imaging, Online shopping

SALT LAKE CITY, Nov. 17, 2022 /PRNewswire-PRWeb/ -- PathologyWatch, a full-service digital dermatopathology solution, welcomes Dr. Joseph Willman, MD, to its team of respected pathologists. Dr. Willman, a dermatopathologist with over two decades of experience, will utilize state-of-the-art digital pathology workflows to deliver optimal patient care to dermatology clinics.

Key Points: 
  • SALT LAKE CITY, Nov. 17, 2022 /PRNewswire-PRWeb/ -- PathologyWatch , a full-service digital dermatopathology solution, welcomes Dr. Joseph Willman, MD, to its team of respected pathologists.
  • With 20 years of experience in dermatopathology, Dr. Willman brings extensive expertise to PathologyWatch.
  • PathologyWatch is the groundbreaking leader of digital dermatopathology services.
  • This can facilitate best-in-class reads and, in some cases, enable additional revenue to the practice by in-housing pathology.

ColdQuanta Expands Leadership Team with Promotion of Chris Wood to Chief Technology Officer and Addition of New Top Talent

Retrieved on: 
Tuesday, October 4, 2022
Solution, International Space Station, VP, YouTube, QC Ware, Die (integrated circuit), Engineering, CSO, National Space Development Agency of Japan, Ecosystem, Quantum, Business development, CTO, Knowledge, David Hilbert, Defense, Multimedia, Mechanics, National Geospatial-Intelligence Agency, View, Wood, Intelligence community, Growth, Senior, NASA, Physics, Program, Element, Politics of the International Space Station, Conference, Forest Law Enforcement and Governance Program, Acquisition, Heel, University, University of Wisconsin–Madison, Intellectual property, CO, JILA, Intelligence, Founder, General Dynamics Mission Systems, University of Colorado Colorado Springs, Microscope, Management, Research

BOULDER, Colo., Oct. 4, 2022 /PRNewswire/ -- ColdQuanta, the global quantum ecosystem leader, today announced it has expanded its leadership team with a stable of quantum experts including: Dr. William Clark as Vice President of Quantum Development, Laura Hale as Vice President of Government Programs, and Steve Matthews, as Vice President of Sales & Business Development for Quantum Information Platforms. VP of Photonic Technologies, Dr. Chris Wood, has been promoted to Chief Technology Officer (CTO). Acting Chief Technology Officer, Dr. Dana Z. Anderson, will serve as Chief Strategy Officer (CSO), guiding the company's long-term quantum strategy. 

Key Points: 
  • VP of Photonic Technologies, Dr. Chris Wood, has been promoted to Chief Technology Officer (CTO).
  • Acting Chief Technology Officer, Dr. Dana Z. Anderson, will serve as Chief Strategy Officer (CSO), guiding the company's long-term quantum strategy.
  • Additionally, ColdQuanta announced the commercial beta launch of Hilbert , the world's first cold atom quantum computer.
  • The name ColdQuanta and the ColdQuanta logo are both registered trademarks of ColdQuanta, Inc.
    View original content to download multimedia: https://www.prnewswire.com/news-releases/coldquanta-expands-leadership-t...

Medtronic receives FDA clearance for next-generation UNiD™ Spine Analyzer with degenerative spine surgery predictive model

Retrieved on: 
Thursday, July 14, 2022
Technology, Goal, Leveque, Security (finance), Surgeon, U.S. Securities and Exchange Commission, Analyser, Solution, LinkedIn, Neuroscience, Webbed toes, Risk, Adult, Patient, Deformity, Spine, Algorithm, Food, Degeneracy, Veni, vidi, vici, Database, Malalignment of the nail plate, Pain, University of Colorado Colorado Springs, FDA, Disability, Twitter, Food and Drug Administration, Intelligence, Health, Anatomical terms of location, University, NYSE, Dentistry, Medical device, Risk management, Medical imaging, Medtronic

DUBLIN, July 14, 2022 /PRNewswire/ -- Medtronic plc (NYSE:MDT), a global leader in healthcare technology, today announced it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for its UNiD™ Spine Analyzer v4.0 planning platform, which includes a new Degen Algorithm for degenerative spine procedures. The algorithm leverages machine learning to help surgeons plan and personalize procedures for patients undergoing lower lumbar spine surgery and predicts spinal compensation mechanisms six months after the operation.

Key Points: 
  • Medtronic is the first and only company to have FDA cleared predictive models for spine surgery.
  • "It is truly exciting to share that we have expanded our UNiD ASI technology to include hardware and software solutions dedicated to helping spine surgeons treat degenerative spinal pathologies, where the majority of spine surgery is performed."
  • Degenerative spine disease is a common health condition and significant cause of disability for many patients worldwide1.
  • Surgical planning, using the UNiD Spine Analyzer, is especially important for degenerative spine procedures, as studies suggest nearly a third of these degenerative patients have a hidden deformity2.