Cognitive development

Ultragenyx Announces Data Demonstrating Treatment with UX111 Results in Significant Reduction in Heparan Sulfate Exposure in Cerebrospinal Fluid Correlated with Improved Long-term Cognitive Function in Patients with Sanfilippo Syndrome Type A (MPS IIIA)

Retrieved on: 
Tuesday, February 6, 2024

These data are from the modified intention to treat group (mITT) in the pivotal Transpher A study (N=17).

Key Points: 
  • These data are from the modified intention to treat group (mITT) in the pivotal Transpher A study (N=17).
  • 8 of 17 patients in the mITT group who reached 24 months post-treatment achieved an overall mean percent reduction from baseline of 51% (p
  • Specifically, 15 of 17 patients had both a reduction in toxic CSF HS exposure and an improvement in cognitive function.
  • Both trials are ongoing, and patients will continue to be followed for a minimum of 5 years following treatment with UX111.

Being an 'authentic' CEO is a job in itself for women

Retrieved on: 
Saturday, December 30, 2023

Prior to that, I’d spent three decades rising up the ranks in the media and university leadership.

Key Points: 
  • Prior to that, I’d spent three decades rising up the ranks in the media and university leadership.
  • It has taken a clean break from the boardroom to clear the mental clutter.
  • One bizarre realisation that has bubbled up is that I haven’t seen my natural hair colour in 40 years.

From the glass ceiling to the glass cliff

  • And of course, there have been advances in breaking the “glass ceiling” that stops women from rising to leadership positions.
  • But research continues to show how women that do reach senior positions are more likely to leave these roles much sooner than men.
  • For example, when an organisation in crisis appoints a woman CEO and then dismisses her for failing to achieve a turnaround.
  • In other words, authenticity is not measured in the same way for male and female leaders.

Working women’s ‘double bind’

  • Hair, clothing choice, tone of voice and non-verbal behaviour are all discussed as ways to achieve this in the accounts I have collected to date.
  • Across industries from fashion to railways, women executives feel their appearance is scrutinised as a measure of their competence in ways men’s clothing and demeanour isn’t.
  • The world desperately needs authentic, ethical and compassionate leadership – by men and women – right now.


Sarah Niblock does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Orchard Therapeutics Receives U.S. FDA Fast Track Designation for OTL-203 in MPS-IH

Retrieved on: 
Thursday, November 30, 2023

BOSTON and LONDON, Nov. 30, 2023 (GLOBE NEWSWIRE) -- Orchard Therapeutics (Nasdaq: ORTX), a global gene therapy leader, today announced the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to OTL-203, an investigational hematopoietic stem cell gene (HSC) therapy being developed for the potential treatment of the Hurler subtype of mucopolysaccharidosis type I (MPS-IH). Fast Track designation is intended to expedite the development of promising medicines that address serious medical needs. Therapeutic candidates that receive Fast Track designation may be eligible for enhanced interactions with the FDA, including potentially quicker submission and review timelines.

Key Points: 
  • Fast Track designation is intended to expedite the development of promising medicines that address serious medical needs.
  • Therapeutic candidates that receive Fast Track designation may be eligible for enhanced interactions with the FDA, including potentially quicker submission and review timelines.
  • “We are encouraged that OTL-203 has been granted Fast Track designation because new treatment options are urgently needed for children with MPS-IH, as the current standard of care is associated with significant morbidity and mortality.
  • Throughout the PoC study, treatment with OTL-203 has been generally well-tolerated with a safety profile consistent with the selected conditioning regimen.

As part of seven outputs being tested and evaluated, ECA announces Pioneering Pilots to Address Tech Challenges as part of World Early Childhood Development (WED) Movement

Retrieved on: 
Monday, November 27, 2023

ABU DHABI, UAE, Nov. 27, 2023 /PRNewswire/ --  Abu Dhabi Early Childhood Authority (ECA) announced the roll out of two key outputs as part of the World Early Childhood Development (WED) Movement.

Key Points: 
  • ABU DHABI, UAE, Nov. 27, 2023 /PRNewswire/ --  Abu Dhabi Early Childhood Authority (ECA) announced the roll out of two key outputs as part of the World Early Childhood Development (WED) Movement.
  • The progress of the pilots will be unveiled at the bi-annual WED Forum and an inaugural Tech Humanity for Children Symposium in 2024.
  • World Early Childhood Development (WED) Movement is a pioneering initiative that unitesglobal and local experts, partners, and innovators to address global Early Childhood Development (ECD) challenges.
  • WED Movement collaborates with key partners and government entities to improve Early Childhood Development (ECD) services and outcomes, through the Abu Dhabi Early Childhood Development Strategy 2035.

As part of seven outputs being tested and evaluated, ECA announces Pioneering Pilots to Address Tech Challenges as part of World Early Childhood Development (WED) Movement

Retrieved on: 
Monday, November 27, 2023

ABU DHABI, UAE, Nov. 27, 2023 /PRNewswire/ --  Abu Dhabi Early Childhood Authority (ECA) announced the roll out of two key outputs as part of the World Early Childhood Development (WED) Movement.

Key Points: 
  • ABU DHABI, UAE, Nov. 27, 2023 /PRNewswire/ --  Abu Dhabi Early Childhood Authority (ECA) announced the roll out of two key outputs as part of the World Early Childhood Development (WED) Movement.
  • The progress of the pilots will be unveiled at the bi-annual WED Forum and an inaugural Tech Humanity for Children Symposium in 2024.
  • World Early Childhood Development (WED) Movement is a pioneering initiative that unitesglobal and local experts, partners, and innovators to address global Early Childhood Development (ECD) challenges.
  • WED Movement collaborates with key partners and government entities to improve Early Childhood Development (ECD) services and outcomes, through the Abu Dhabi Early Childhood Development Strategy 2035.

Learn Wall Street Teaches Teenagers the Power of Investing

Retrieved on: 
Tuesday, October 3, 2023

NEW YORK, Oct. 2, 2023 /PRNewswire/ -- Learn Wall Street, a new after-school program that teaches teenagers about finance and investing, launched its first semester in September.

Key Points: 
  • NEW YORK, Oct. 2, 2023 /PRNewswire/ -- Learn Wall Street, a new after-school program that teaches teenagers about finance and investing, launched its first semester in September.
  • "Financial knowledge is somewhat unique in comparison to other subjects like math or history," says Raji Khabbaz, co-founder of Learn Wall Street.
  • Learn Wall Street trying to make finance and investing interesting in the same way.
  • Learn Wall Street is open to teenagers in grades 9-12.

Novo Integrated Sciences’ IoNovo for Kids Granted Registration Number and Regulatory Approval by Turkey’s Ministry of Health

Retrieved on: 
Wednesday, September 13, 2023

Novo Integrated Sciences, Inc. (NASDAQ: NVOS) (the “Company” or “Novo”), today announced that its IoNovo for Kids pure iodine oral spray has been granted a registration number and received regulatory approval by Turkey’s Ministry of Health as a dietary supplement determined to be safe, effective, of high quality, and eligible for sale in Turkey.

Key Points: 
  • Novo Integrated Sciences, Inc. (NASDAQ: NVOS) (the “Company” or “Novo”), today announced that its IoNovo for Kids pure iodine oral spray has been granted a registration number and received regulatory approval by Turkey’s Ministry of Health as a dietary supplement determined to be safe, effective, of high quality, and eligible for sale in Turkey.
  • With this registration, Novo’s two IoNovo Iodine related products have full approval for distribution and sale throughout Turkey.
  • IoNovo Iodine is directly absorbed into the bloodstream through a precise oral spray dosage without interacting with the oral micro-biome or any bacteria or viruses.
  • All of Novo’s IoNovo products are designed to be delivered via oral spray which is proven to be significantly more effective in absorption than pill or gel capsules.

2023 LINGOKIDS YOUTH SCREEN TIME STUDY: HOW TO HELP KIDS NOT BECOME 'SCREEN ZOMBIES'

Retrieved on: 
Tuesday, August 29, 2023

Only 50% of parents are very involved in monitoring their children's screen time.

Key Points: 
  • Only 50% of parents are very involved in monitoring their children's screen time.
  • "Interactive screen time is a language of our time, and it is how we learn, communicate, create and connect with others.
  • The study revealed that only 50% of parents are actively involved in monitoring and regulating their children's screen time.
  • By setting good examples and fostering safe and active screen time, parents can ensure that their children's digital experiences are enriching and fun.

2023 LINGOKIDS YOUTH SCREEN TIME STUDY: HOW TO HELP KIDS NOT BECOME 'SCREEN ZOMBIES'

Retrieved on: 
Tuesday, August 29, 2023

Only 50% of parents are very involved in monitoring their children's screen time.

Key Points: 
  • Only 50% of parents are very involved in monitoring their children's screen time.
  • "Interactive screen time is a language of our time, and it is how we learn, communicate, create and connect with others.
  • The study revealed that only 50% of parents are actively involved in monitoring and regulating their children's screen time.
  • By setting good examples and fostering safe and active screen time, parents can ensure that their children's digital experiences are enriching and fun.

Novo Integrated Sciences’ IoNovo Iodine Granted Registration Number and Regulatory Approval by Turkey’s Ministry of Health

Retrieved on: 
Tuesday, August 22, 2023

Novo Integrated Sciences, Inc. (NASDAQ: NVOS) (the “Company” or “Novo”), today announced that its IoNovo Iodine product has been granted a registration number and received regulatory approval by Turkey’s Ministry of Health as a dietary supplement determined to be safe, effective, of high quality, and eligible for sale in Turkey.

Key Points: 
  • Novo Integrated Sciences, Inc. (NASDAQ: NVOS) (the “Company” or “Novo”), today announced that its IoNovo Iodine product has been granted a registration number and received regulatory approval by Turkey’s Ministry of Health as a dietary supplement determined to be safe, effective, of high quality, and eligible for sale in Turkey.
  • For decades, the global medical community has recognized Iodine as an essential micronutrient that assists the thyroid to produce T3 and T4 hormones needed for a healthy metabolism, immune system, increased energy levels, and cognitive development, Additionally, Iodine is known to promote healthy skin, nails, and hair.
  • IoNovo Iodine is directly absorbed into the bloodstream through a precise oral spray dosage without interacting with the oral micro-biome or any bacteria or viruses.
  • All of Novo’s IoNovo products are designed to be delivered via oral spray which is proven to be significantly more effective in absorption than pill or gel capsules.