Bypass surgery

CMR Surgical announces over 20,000 surgical cases completed using Versius

Retrieved on: 
Thursday, March 21, 2024
ICG, Colorectal surgery, CMR, Elective surgery, Nissen fundoplication, CE, Communication, Patient, Contraindication, Hospital, North Hertfordshire, Bleeding, Sale, Cancer, CMR Surgical, General surgery, MD, Thought, Surgeon, Rib cage, Bypass surgery, Pain, GMT, Cholecystectomy, Fatigue, MAS, Dentistry

CMR Surgical (CMR) – the global surgical robotics business – has today announced that over 20,000 Versius surgical cases have now been completed as the Company works with hospitals and surgeons around the world to bring minimal access surgery to everyone who needs it.

Key Points: 
  • CMR Surgical (CMR) – the global surgical robotics business – has today announced that over 20,000 Versius surgical cases have now been completed as the Company works with hospitals and surgeons around the world to bring minimal access surgery to everyone who needs it.
  • The Versius Surgical Robotic System is a small, modular and versatile surgical robot used for soft tissue surgery.
  • Over 75% of hospitals who have adopted Versius are using the system across two or more surgical specialties, leading to some hospitals around the world purchasing more than one system.
  • Through the Versius Connect app, Versius Trainer and CMR clinical registry, Versius unleashes a wealth of insights to ultimately improve surgical care.

CMR Surgical announces over 20,000 surgical cases completed using Versius

Retrieved on: 
Thursday, March 21, 2024
ICG, Colorectal surgery, CMR, Elective surgery, Nissen fundoplication, CE, Communication, Patient, Contraindication, Hospital, North Hertfordshire, Bleeding, Sale, Cancer, CMR Surgical, General surgery, MD, Thought, Surgeon, Rib cage, Bypass surgery, Pain, GMT, Cholecystectomy, Fatigue, MAS, Dentistry

CMR Surgical (CMR) – the global surgical robotics business – has today announced that over 20,000 Versius surgical cases have now been completed as the Company works with hospitals and surgeons around the world to bring minimal access surgery to everyone who needs it.

Key Points: 
  • CMR Surgical (CMR) – the global surgical robotics business – has today announced that over 20,000 Versius surgical cases have now been completed as the Company works with hospitals and surgeons around the world to bring minimal access surgery to everyone who needs it.
  • The Versius Surgical Robotic System is a small, modular and versatile surgical robot used for soft tissue surgery.
  • Over 75% of hospitals who have adopted Versius are using the system across two or more surgical specialties, leading to some hospitals around the world purchasing more than one system.
  • Through the Versius Connect app, Versius Trainer and CMR clinical registry, Versius unleashes a wealth of insights to ultimately improve surgical care.

Levita® Magnetics Achieves First Deployment of MARS™ Surgical System in a Private Institution

Retrieved on: 
Thursday, April 4, 2024
Bariatric surgery, Patient, Hospital, Prostate, Magnetism, Surgeon, Cleveland Clinic, Bypass surgery, Pain, Cholecystectomy, FDA, Health, Medical imaging

MOUNTAIN VIEW, Calif., April 4, 2024 /PRNewswire/ -- Levita Magnetics, whose mission is to expand patient access to advanced surgical care, today celebrates a key advancement in minimally invasive surgery with the deployment of its MARS surgical system at a North Texas-based hospital. This marks a significant milestone as the first implementation of the MARS system in a private institution, representing a critical development in the global expansion of the technology. This expansion follows Levita's recent international introduction in Chile and its first commercial application in the U.S. at Cleveland Clinic in late 2023.

Key Points: 
  • This marks a significant milestone as the first implementation of the MARS system in a private institution, representing a critical development in the global expansion of the technology.
  • "The introduction of the MARS system in Dallas represents a meaningful and impactful advancement in our surgical capabilities," said Dr. Chad Carlton.
  • The MARS system, an FDA-approved surgical platform, innovatively combines magnetic technology and machinery to minimize incisions, enhance visualization, and streamline laparoscopic surgery.
  • MARS builds on the clinical benefits of the Levita Magnetic Surgical System®, incorporating proprietary Dynamic Magnetic Positioning technology with dual surgeon-controlled arms.

Reflection paper on investigation of pharmacokinetics in the obese population - Scientific guideline

Retrieved on: 
Wednesday, February 14, 2024
Leptin, PD, Metabolism, Toxicity, Body composition, Ciprofloxacin, Clinical Pharmacokinetics, Water, LBW, Perfusion, LBM, Canadian International Council, AUC, PLOS One, Bariatric surgery, Clopidogrel, CYP, Breast, Health, DNA-binding protein, BMC Public Health, Pharmacology, BMI, CRP, Pharmaceutical Research (journal), Organ, Draft, Guideline, Bypass surgery, WHO, Ageing, INT, Pharmacokinetics, Liver, Bioavailability, Chronic liver disease, Human, Incidence, Committee, Absorption, TBW, Cardiovascular disease, Anatomy, CYP2C19, PBPK, Cmax, Factorization of polynomials, European, Lancet, CHMP, Journal, NASH, Pharmacotherapy, Adipose tissue, Non-alcoholic fatty liver disease, Journal of Clinical Investigation, Medication package insert, Overweight, NPS MedicineWise, Permeability, Benzodiazepine, Meta-analysis, Liver disease, Half-life, Acetylcholine, Ciclosporin, AAG, Kinetics, Midazolam, Kidney, Safety, Biomarker, Clinical Pharmacology & Therapeutics, Peptide, Classification, Hypertension, Metabolic syndrome, Acute coronary syndrome, Insulin resistance, Fatty liver disease, CYP2E1, Lithium, Body mass index, Reproduction, EMA, IBW, Injection, Anker, NCA, Enzyme, Inflammation, Cancer, Weight loss, Gastrointestinal tract, Cardiac output, Public health, Adipokine, CYP2C9, E pluribus unum, Physiology, Agency, Risk, Steroid, Lymph, CYP2D6, BSA, GI, Cytokine, Systematic review, Vaccine

Reflection paper on investigations of pharmacokinetics in

Key Points: 
    • Reflection paper on investigations of pharmacokinetics in
      the obese population
      Table of contents
      1.
    • References .............................................................................................. 9

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 2/12

      1.

    • This is considered
      a shortcoming that is potentially compounded by obese patients often being poorly represented in
      clinical studies.
    • The specific aims of this reflection paper are to:
      ?

      describe how the effects of obesity can be investigated during clinical medicinal product
      development.

    • ?

      provide recommendations on when investigations of the effect of obesity on the PK of a
      medicinal product should be particularly considered.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 3/12

      ?

      discuss how to reflect PK (and/or PK/PD) findings in weight/weight-based dosing
      recommendations.

    • Absorption
      Reduced rate of absorption linked to locally reduced blood flow (8) is reported for the subcutaneous
      and transdermal routes in obese subjects.
    • Distribution
      The distribution of medicinal products is driven by body composition, regional blood flow and binding to
      tissue and plasma proteins.
    • Obese subjects have a larger absolute lean body weight (LBW) as well as fat mass.
    • The physicochemical properties of a medicinal product (lipophilicity, polarity, molecular size, and
      degree of ionization) influence its distribution in the body.
    • In BMI class III obese
      subjects, the blood flow per gram of fat is significantly lower than that observed in class I obese or
      lean subjects (4).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 4/12

      An increased amount of alpha-1-acid-glycoprotein (AAG), linked to a chronic inflammatory state, is
      reported in obese individuals.

    • Fatty infiltrations are present in the liver for 90% of obese subjects, with the extent of the infiltrations
      being proportional to the degree of obesity.
    • In some cases, in particular for CYP3A4 metabolized medicinal products,
      bodyweight normalized clearance can be lower in obese patients (23).
    • Based on presently available data, it has been suggested that uptake transporters

      Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 5/12

      are downregulated while efflux transporters may be upregulated (31).

    • Platelet hyper-reactivity is also observed,
      which can impair the response to anti-platelet medicinal products in obese patients (42, 43).
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 6/12

      3.

      the medicinal product properties and scientific literature indicate that obesity may lead to a
      marked effect on elimination and/or distribution or on the PK/PD relationship.

    • These
      models may aid in extrapolating the known efficacy and safety in the non-obese population to the
      obese population.
    • The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients
      Before and One Year After Bariatric Surgery.
    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 11/12

      41.

    • Reflection paper on investigations of pharmacokinetics in the obese population
      EMA/CHMP/535116/2016

      Page 12/12

New York Bariatric Group Celebrates 17 Doctors Named Top Doctors by Castle Connolly

Retrieved on: 
Tuesday, February 6, 2024
Multimedia, Bariatric surgery, Obesity, Patient, NYBG, Castle Connolly Medical, Physician, Health, Bariatrics, Bypass surgery, Nursing

The following New York Bariatric Group doctors have earned this esteemed recognition:

Key Points: 
  • The following New York Bariatric Group doctors have earned this esteemed recognition:
    The doctors at New York Bariatric Group express deep gratitude for this esteemed honor.
  • New York Bariatric Group remains at the forefront of advancing weight loss solutions, and the acknowledgment from Castle Connolly reinforces the group's dedication to excellence in healthcare.
  • New York Bariatric Group (NYBG) is a nationally renowned bariatric practice.
  • Utilizing minimally invasive techniques, technology, talent, and experience, New York Bariatric Group is the elite institution for the treatment of obesity.

Leading Journal Unveils Groundbreaking Efficacy of Novel Treatment for Obesity, Diabetes, and Liver Disease

Retrieved on: 
Thursday, January 18, 2024
Obesity, DSM-IV codes, Patient, Weight gain, Overalls, MASH, Bypass surgery, Insulin, Safety, King's College London, Glucose, Liver, BMI, Stomach, Gastroenterology, Endoscopy, Medical device

The study, authored by an international team of prominent researchers, appeared in Gut, which is the leading international journal in the field of gastroenterology.

Key Points: 
  • The study, authored by an international team of prominent researchers, appeared in Gut, which is the leading international journal in the field of gastroenterology.
  • Substantial improvements in how the body handles insulin and reduces glucose in the liver compared to controls.
  • Markedly improved response to insulin, enhanced overall body’s use of glucose, and beneficial changes in metabolic health-related gut bacteria.
  • Should the upcoming trials, as anticipated, confirm the safety and efficacy demonstrated in animal studies, this device is poised to transform the treatment of severe and morbid obesity in the years ahead.

Global Surgical Robots Market Forecast Report to 2030 - Partner & Customer Ecosystem Competitive Index & Regional Footprints - ResearchAndMarkets.com

Retrieved on: 
Wednesday, January 24, 2024
Biotechnology, Surgery, Health, Robotics, Technology, Artificial intelligence, CMR Surgical, Renishaw plc, Infection, Research, Bypass surgery, Hospital, Intuitive Surgical, Partner, Others, Surgeon, Stryker Corporation, AI, Government, Appendectomy, Algorithm, Risk, Johnson & Johnson, USD, Pain, Medtronic, Hysterectomy, Instrument, Machine learning, Colectomy, Region, Prostatectomy, Siemens Healthineers, Growth, Medical device

The "Global Surgical Robots Market 2030 by Product Type, Application, End-user, and Region - Partner & Customer Ecosystem Competitive Index & Regional Footprints" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Surgical Robots Market 2030 by Product Type, Application, End-user, and Region - Partner & Customer Ecosystem Competitive Index & Regional Footprints" report has been added to ResearchAndMarkets.com's offering.
  • Major players Surgical Robots Market include: Stryker Corporation, Medrobotics, Smith & Nephew, TransEnterix Surgical, Inc., Renishaw plc., Intuitive Surgical, Medtronic, THINK Surgical, Inc., Zimmer Biomet, Asensus Surgical, Siemens Healthineers, CMR Surgical, Johnson & Johnson, Renishaw Plc.
  • The demand for these computer-assisted surgical systems is substantial, being utilized in open surgeries, laparoscopic procedures, and flexible endoscopic procedures.
  • One key trend in the Surgical Robots Market is the integration of artificial intelligence (AI) and machine learning (ML) technologies into surgical robotic systems.

Global Surgical Robots Market Report 2024 - Projected at USD 7.3 Billion by 2030: Integration of AI & High Demand for Minimally Invasive Surgeries Propel North America to the Forefront

Retrieved on: 
Wednesday, January 24, 2024
Artificial intelligence, CMR Surgical, Renishaw plc, Infection, Research, Bypass surgery, Hospital, Intuitive Surgical, Partner, Others, Surgeon, Stryker Corporation, AI, Government, Appendectomy, Algorithm, Risk, Johnson & Johnson, USD, Pain, Medtronic, Hysterectomy, Instrument, Machine learning, Colectomy, Region, Prostatectomy, Siemens Healthineers, Growth, Medical device

Major players Surgical Robots Market include: Stryker Corporation, Medrobotics, Smith & Nephew, TransEnterix Surgical, Inc., Renishaw plc., Intuitive Surgical, Medtronic, THINK Surgical, Inc., Zimmer Biomet, Asensus Surgical, Siemens Healthineers, CMR Surgical, Johnson & Johnson, Renishaw Plc.

Key Points: 
  • Major players Surgical Robots Market include: Stryker Corporation, Medrobotics, Smith & Nephew, TransEnterix Surgical, Inc., Renishaw plc., Intuitive Surgical, Medtronic, THINK Surgical, Inc., Zimmer Biomet, Asensus Surgical, Siemens Healthineers, CMR Surgical, Johnson & Johnson, Renishaw Plc.
  • The use of medical robotic systems has become widespread in the fields of gynaecology and cosmetology, particularly for minimally invasive surgeries.
  • The demand for these computer-assisted surgical systems is substantial, being utilized in open surgeries, laparoscopic procedures, and flexible endoscopic procedures.
  • One key trend in the Surgical Robots Market is the integration of artificial intelligence (AI) and machine learning (ML) technologies into surgical robotic systems.

Rezolute Announces Further Evidence of RZ358’s Efficacy in Tumor-Mediated Hyperinsulinism

Retrieved on: 
Wednesday, October 11, 2023
Birth, The New England Journal of Medicine, MD, Rezolution Pictures, FDA, Rare, Bypass surgery, Hyperinsulinism, Neoplasm, Hypoglycemia, EAP, Patient, Pharmaceutical industry

The Company previously reported on the successful use of RZ358 for a patient with refractory hypoglycemia due to metastatic insulinoma, which has since been published in a recent edition of the New England Journal of Medicine (389;8).

Key Points: 
  • The Company previously reported on the successful use of RZ358 for a patient with refractory hypoglycemia due to metastatic insulinoma, which has since been published in a recent edition of the New England Journal of Medicine (389;8).
  • Notably, the individual with metastatic insulinoma has remained on RZ358 for nearly a year.
  • “We believe that this provides further validation of our long-held view of hyperinsulinism as a group of related conditions, and RZ358 as a potential universal treatment for any of the various causes of hyperinsulinism, whether congenital, induced by gastric bypass, or mediated by tumors.
  • We are in the process of evaluating next steps to develop RZ358 in these additional indications.”

26th World Congress of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) - Obesity, bariatric surgery 'cuts' the risk of cancer: -25%

Retrieved on: 
Monday, August 28, 2023
Weight, Male, Federico, University, Unimed, Harvard University, Weight loss, Cancer, Woman, Research, DSM-IV codes, Colon, Congress, Incidence, Bariatric surgery, Patient, Physician, Risk, Angrisani, Bypass surgery, Mortality, General surgery, Duodenal switch, Birth control, Dentistry, Obesity

NAPLES, Italy, Aug. 28, 2023 /PRNewswire/ -- Losing weight with bariatric surgery can have a major impact on the risk of developing cancer.

Key Points: 
  • NAPLES, Italy, Aug. 28, 2023 /PRNewswire/ -- Losing weight with bariatric surgery can have a major impact on the risk of developing cancer.
  • Almost 22,000 patients undergoing bariatric surgery were involved and matched to be compared with non-operated people with obesity.
  • The risk of cancer in women, who are the majority of people undergoing bariatric surgery, is significantly reduced.
  • People with obesity and physicians should take these benefits seriously into consideration when evaluating and discussing bariatric surgery with their patients.