Asbestosis

Ocean Biomedical (NASDAQ: OCEA) Announces New Patent for Anti-Fibrosis Discovery with Allowance in Alcoholic Liver Disease and Multiple Fibrotic Conditions, Leading Causes of Death in the U.S.

Retrieved on: 
Tuesday, August 29, 2023
Patent, Human, Ocean Biomedical, NASH, RI, United States Patent and Trademark Office, Lupus, Asbestosis, Pulmonary fibrosis, Fibrosis, HPS, EPA, Connective tissue, Silicosis, Hermansky–Pudlak syndrome, Fatty liver disease, IPF, Alcoholic liver disease, Idiopathic pulmonary fibrosis, Rheumatoid arthritis, Scleroderma, Pharmaceutical industry, MD

Providence, RI, Aug. 29, 2023 (GLOBE NEWSWIRE) -- Ocean Biomedical, Inc. (NASDAQ: OCEA) announced today that the United States Patent and Trademark Office has issued a patent covering Ocean’s anti-Chitinase 1 small molecule candidate.

Key Points: 
  • Patent granted for use in IPF, HPS, alcoholic liver disease, nonalcoholic steatohepatitis (NASH), and scleroderma.
  • Providence, RI, Aug. 29, 2023 (GLOBE NEWSWIRE) -- Ocean Biomedical, Inc. (NASDAQ: OCEA ) announced today that the United States Patent and Trademark Office has issued a patent covering Ocean’s anti-Chitinase 1 small molecule candidate.
  • Targeted diseases include alcoholic liver disease, idiopathic pulmonary fibrosis (IPF), scleroderma, nonalcoholic steatohepatitis (NASH), and Hermansky-Pudlak Syndrome (HPS), a rare disease that currently has no known treatments.
  • Ocean’s approach has shown an 85%–90% reduction in collagen accumulation in four different IPF and HPS pulmonary fibrosis animal models.

Incremental environmental change can be as hazardous as a sudden shock – managing these ‘slow-burning’ risks is vital

Retrieved on: 
Thursday, August 10, 2023
Food, Carcinogen, Atmosphere, Garden, Cancer, Risk management, Risk assessment, Asbestosis, Resource Management Act 1991, Silicosis, Soil, Resource management, Risk, Asbestos, Water, City, Landslide, Climate change, Health, Increment, Environment, Legislation, Agriculture, Environmental remediation

Although risk assessment and management procedures try to account for hazards in a systematic way, they often overlook risks arising from incremental and seemingly insignificant environmental changes.

Key Points: 
  • Although risk assessment and management procedures try to account for hazards in a systematic way, they often overlook risks arising from incremental and seemingly insignificant environmental changes.
  • But over time, or when aggregated, incremental changes can lead to significant impacts on human health and wellbeing.
  • Incremental changes in our environments can evade regulation if their effects are slow-burning, uncertain, or there is a time lag between cause and effect.
  • However, given the requirement for significant change, it is hard to see how these provisions could be used proactively to manage incremental changes.

Respirable mineral dust

    • They can gradually accumulate in the lungs, causing diseases such as pleural changes, silicosis and asbestosis, even cancer.
    • However, the causes of frequent but low-level exposures to mineral dust have often escaped regulation.

Cumulative effects of incremental loss of green space

    • Our built environment of impermeable surfaces is slowly encroaching on urban green spaces and gardens.
    • Instead, consent applications are assessed on their individual impacts and there are few mechanisms to sufficiently assess and manage aggregate and cumulative effects.

What needs to happen

    • If we continue to only consider the immediate and local effects from individual actions, we are not able to protect people from future cumulative consequences.
    • Marc Tadaki receives funding from Te Apārangi Royal Society of New Zealand and the Ministry of Business, Innovation and Employment.
    • Martin Brook receives funding from Royal Society Te Apārangi, Toka Tū Ake EQC, and Ministry of Business, Innovation and Employment.
    • He is a chartered geologist (CGeol) with the Geological Society of London, and a member of Engineering New Zealand (MEngNZ).

NZ workers have unacceptably high exposures to carcinogens – they need better protection and long-term health monitoring

Retrieved on: 
Thursday, June 29, 2023
International, NZCS, Human, Employment, Carcinogen, Prevalence, IARC, Group 1, Group 3, Agriculture, Farmer, Workplace, Eye, Electricity, Data collection, Woman, International Agency for Research on Cancer, Emergency, Asbestosis, Death, Solvent, Forestry, Man, Health authority, Work, Population, UV, Risk, Styrene, Mining, Water, Occupation, Solution, Health, Hydrocarbon, Periodic table, Research, Smoking, WorkSafe New Zealand, Benzene, Disease, Personal protective equipment, Mobile phone, Oil, Mineral wool, Mineral oil, Nursing, Pacific Ocean, Cancer

The New Zealand Carcinogens Survey (NZCS), commissioned by WorkSafe New Zealand, was the first to examine the prevalence of occupational carcinogens in the working population.

Key Points: 
  • The New Zealand Carcinogens Survey (NZCS), commissioned by WorkSafe New Zealand, was the first to examine the prevalence of occupational carcinogens in the working population.
  • Workers in primary industries are exposed to the highest number of carcinogens at any level.
  • Māori and Pacific workers and men are the most likely to be exposed to at least one carcinogen.

Work-related exposures


    Work-related disease is estimated to account for 750-900 deaths a year in New Zealand. Cancer contributes to about half of these deaths and at least a third of work-related hospitalisations. These figures are largely based on overseas estimates applied to Aotearoa New Zealand health data. Establishing the number of workplace injuries is relatively straightforward but investigation of work-related cancers is much more difficult because:
    Therefore, understanding the prevalence, frequency and distribution of exposure to work-related carcinogens is crucial.

    Read more:
    Nail salon workers suffer chemical exposures that can be like working at a garage or a refinery

Which exposures matter?


    How do we know which workplace exposures contribute to cancer risk? The International Agency for Research on Cancer (IARC) regularly undertakes expert reviews of the relevant scientific literature to identify cancer-causing substances and practices. They classify exposures on the basis of the quality of evidence as:
    • Until the NZCS report, New Zealand-specific data on work exposures to carcinogens have been lacking.
    • It used a web-based exposure-assessment programme to estimate the likelihood of exposures and probable level based on questions to workers about substances, jobs and specific tasks.

What is to be done?

    • However, it is important to concentrate on the unmistakable evidence that a large number of people are exposed to high levels of workplace carcinogens.
    • But data alone are not sufficient; they need to inform action.
    • There are too many examples of Aotearoa being slower than other countries to act when sufficient evidence exists.
    • New Zealand was the last country in the world to halt the production of the toxic dioxin-contaminated herbicide 2,4,5-T, in 1987.
    • A lack of dedicated health services for occupational health hampers progress in addressing work-related diseases in New Zealand.

Ocean Biomedical (NASDAQ: OCEA) Announces Notice of Allowance for U.S. Patent Application for Breakthrough Pulmonary Fibrosis Treatments Issued to Scientific Co-founder Dr. Jack A. Elias.

Retrieved on: 
Thursday, April 20, 2023
Yale University, Patent, Kidney failure, Ocean Biomedical, Idiopathic pulmonary fibrosis, Therapy, Prevalence, NASH, Critical Care Medicine (journal), RI, United States Patent and Trademark Office, University, Survival, Dean, Yale New Haven Hospital, Research, Asbestosis, Pulmonary fibrosis, Pharmacotherapy, Fibrosis, HPS, Science, Silicosis, Patient, Chandos Chair of Medicine and Anatomy, Hermansky–Pudlak syndrome, Brown University, IPF, Alcoholic liver disease, IND, Biology, Scleroderma, Pharmaceutical industry, Medicine

This patent allowance covers pulmonary fibrosis caused by multiple conditions including: idiopathic pulmonary fibrosis (IPF), genetic pulmonary fibrosis such as Hermansky-Pudlak Syndrome (HPS), chemotherapy and radiation-induced pulmonary fibrosis, and exposure-induced interstitial lung diseases including asbestosis and silicosis.

Key Points: 
  • This patent allowance covers pulmonary fibrosis caused by multiple conditions including: idiopathic pulmonary fibrosis (IPF), genetic pulmonary fibrosis such as Hermansky-Pudlak Syndrome (HPS), chemotherapy and radiation-induced pulmonary fibrosis, and exposure-induced interstitial lung diseases including asbestosis and silicosis.
  • A Notice of Allowance is issued after the USPTO examines a patent application and determines that the applicant should be granted a patent from the application.
  • Ocean Biomedical anticipates that a patent will be issued by the USPTO from Dr. Elias’ application in the coming months.
  • In four pulmonary fibrosis animal models, Ocean Biomedical’s OCF-203 has shown an 85% – 90% reduction in collagen accumulation.

HONX, Inc. Bankruptcy Establishes Deadline for Filing Claims Related to Current Asbestos Injury

Retrieved on: 
Tuesday, January 10, 2023
Lung cancer, Oil refinery, Lindsey Oil Refinery, Asbestos-related diseases, Asbestos, Otorhinolaryngology, Esophageal cancer, Laryngeal cancer, Unsecured guarantor loan, Stomach cancer, Pneumoconiosis, Mesothelioma, Asbestosis, Official Committee of Equity Security Holders, Oil

Workers at this Oil Refinery (and family members and others who came into contact with these workers) may have been exposed to asbestos.

Key Points: 
  • Workers at this Oil Refinery (and family members and others who came into contact with these workers) may have been exposed to asbestos.
  • Virtually all oil refineries built before 1980 used or contained products with asbestos.
  • Even if an individual's exposure to asbestos was many years ago, this notice could affect them as asbestos-related illness can occur decades after the exposure to asbestos.
  • Claims may also be filed on behalf of a family member who is deceased, incapacitated, or a minor.

HONX, Inc. Bankruptcy Establishes Deadline for Filing Claims Related to Current Asbestos Injury

Retrieved on: 
Tuesday, January 10, 2023
Lung cancer, Oil refinery, Lindsey Oil Refinery, Asbestos-related diseases, Asbestos, Otorhinolaryngology, Esophageal cancer, Laryngeal cancer, Unsecured guarantor loan, Stomach cancer, Pneumoconiosis, Mesothelioma, Asbestosis, Official Committee of Equity Security Holders, Oil

Workers at this Oil Refinery (and family members and others who came into contact with these workers) may have been exposed to asbestos.

Key Points: 
  • Workers at this Oil Refinery (and family members and others who came into contact with these workers) may have been exposed to asbestos.
  • Virtually all oil refineries built before 1980 used or contained products with asbestos.
  • Even if an individual's exposure to asbestos was many years ago, this notice could affect them as asbestos-related illness can occur decades after the exposure to asbestos.
  • Claims may also be filed on behalf of a family member who is deceased, incapacitated, or a minor.

Global Respiratory Partnering Directory/Report 2021: Comprehensive Access to 850+ Deal Records - Deal Trends, Players and Financials - ResearchAndMarkets.com

Retrieved on: 
Monday, March 14, 2022
General Health, Pharmaceutical, Health, Other Health, Shortness of breath, Hypersensitivity pneumonitis, Pulmonary hypertension, Contract, Research, Finance, Nasal congestion, Bronchitis, Asthma, Chronic obstructive pulmonary disease, Acute respiratory distress syndrome, Respiratory disease, Players, Respiratory tract infection, Silicosis, Idiopathic pulmonary fibrosis, Technology, Sarcoidosis, Coalworker's pneumoconiosis, Pulmonary embolism, Chest pain, Occupational lung disease, Allergic rhinitis, Sales, Poultry, Asbestosis, Sinusitis, Cough, Global, Snoring, Pneumonia

The "Global Respiratory Partnering 2010-2021: Deal Trends, Players and Financials" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Respiratory Partnering 2010-2021: Deal Trends, Players and Financials" report has been added to ResearchAndMarkets.com's offering.
  • The Global Respiratory Partnering 2010 to 2021 report provides comprehensive access to available deals and contract documents for over 850 respiratory deals.
  • The report takes readers through the comprehensive Respiratory disease deal trends, key players and top deal values allowing the understanding of how, why and under what terms companies are currently entering Respiratory deals.
  • Global Respiratory Partnering 2010 to 2021 includes:
    In Global Respiratory Partnering 2010 to 2021, available deals and contracts are listed by:

Global Occupational Health Market Forecast to 2028 - COVID-19 Impact and Analysis - ResearchAndMarkets.com

Retrieved on: 
Tuesday, March 1, 2022
General Health, Professional Services, Health, Human Resources, Conditional sentence, Workplace, Disorder, Growth, Prevalence, Diagnosis, Hearing loss, Awareness, Asthma, Noise, COVID-19, Industry, Medicine, Occupational medicine, Safety, Mental health, Occupational safety and health, Geography, Occupational Safety and Health Act 1994, Injury, Asbestosis, CAGR, Time, Personal protective equipment, Marketing, Agriculture

The "Occupational Health Market Forecast to 2028 - COVID-19 Impact and Global Analysis - by Type" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Occupational Health Market Forecast to 2028 - COVID-19 Impact and Global Analysis - by Type" report has been added to ResearchAndMarkets.com's offering.
  • Factors such as increasing prevalence of chronic diseases and rising awareness of personalized medicines are boosting the occupational health market growth.
  • Occupational health is a branch of medicine that emphasizes on physical and mental health along with wellbeing of employees at the workplace.
  • Scrutinize in-depth global market trends and outlook coupled with the factors driving the occupational health market, as well as those hindering it.

Global Respiratory Equipment Market Size & Forecast Report 2022-2026 with Impact Analysis of COVID-19 - ResearchAndMarkets.com

Retrieved on: 
Tuesday, February 15, 2022
Medical Devices, Health, Philips, Degenerative disease, Patient, Growth, Neuromuscular Disorders, Carbon, Medtronic, CPAP, Non-invasive ventilation, ResMed, Fisher & Paykel Healthcare, Conditional sentence, Respiratory disease, Tuberculosis, Population, Pneumonia, Disease, Diagnosis, COVID-19, Asbestosis, Respiration, Industry, Dietary supplement

The "Global Respiratory Equipment Market: Size & Forecast with Impact Analysis of COVID-19 (2022-2026 Edition)" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Respiratory Equipment Market: Size & Forecast with Impact Analysis of COVID-19 (2022-2026 Edition)" report has been added to ResearchAndMarkets.com's offering.
  • Global Respiratory Equipment Market report provides an in-depth analysis of the global respiratory equipment market including a detailed description of the impact of COVID-19, market sizing and growth.
  • Respiratory equipment includes medical equipment that assists patients with respiration in a severe medical situation.
  • The global respiratory equipment market has increased progressively over the years and the market is further expected to propel at a steady pace during the forecasted years 2022 to 2026.

Center for Asbestos Related Disease (CARD) Article Illuminates High Levels of Asbestos Related Mortality

Retrieved on: 
Thursday, January 20, 2022
Mortality, Patient, Poison, Hope, Asbestosis, CARD, Occupational medicine, Death, Agency, American Journal, Cancer, Public health, Center, History, Asbestos, ATSDR, Asbestos-related diseases, Multimedia, Degenerative disease, American Journal of Industrial Medicine, Awareness, Pharmaceutical industry

These findings illuminate the high levels of asbestos related mortality associated with Libby Amphibole.

Key Points: 
  • These findings illuminate the high levels of asbestos related mortality associated with Libby Amphibole.
  • Mortality from asbestos related disease in this group was 55%, with death from asbestosis or asbestos related pleural fibrosis accounting for 70% and asbestos related cancers the other 30%.
  • We are available for consultation regarding amphibole asbestos and asbestos related disease screening for those who qualify under our grant.
  • The Center for Asbestos Related Disease (CARD) has emerged as a national center of excellence in addressing healthcare issues associated with Libby Amphibole (previously called tremolite) asbestos.