Swelling

Human medicines European public assessment report (EPAR): Xolair, omalizumab, Date of authorisation: 25/10/2005, Revision: 49, Status: Authorised

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Xolair, omalizumab, Date of authorisation: 25/10/2005, Revision: 49, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Xolair, omalizumab, Date of authorisation: 25/10/2005, Revision: 49, Status: Authorised

Human medicines European public assessment report (EPAR): Bimervax, COVID-19 Vaccine (recombinant, adjuvanted), Date of authorisation: 30/03/2023, Revision: 3, Status: Authorised

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Bimervax, COVID-19 Vaccine (recombinant, adjuvanted), Date of authorisation: 30/03/2023, Revision: 3, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Bimervax, COVID-19 Vaccine (recombinant, adjuvanted), Date of authorisation: 30/03/2023, Revision: 3, Status: Authorised

Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41[...]

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA vaccine,elasomeran,elasomeran / imelasomeran,elasomeran / davesomeran,andusomeran, Date of authorisation: 06/01/2021, Revision: 41, Status: Authorised

Human medicines European public assessment report (EPAR): Nepexto, etanercept, Date of authorisation: 20/05/2020, Revision: 12, Status: Authorised

Retrieved on: 
Tuesday, January 2, 2024

Human medicines European public assessment report (EPAR): Nepexto, etanercept, Date of authorisation: 20/05/2020, Revision: 12, Status: Authorised

Key Points: 


Human medicines European public assessment report (EPAR): Nepexto, etanercept, Date of authorisation: 20/05/2020, Revision: 12, Status: Authorised

Atom Bioscience Receives FDA IND Clearance for Clinical Trial of ABP-745 for Acute Gout

Retrieved on: 
Tuesday, January 2, 2024

Atom Bioscience (Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd.), a clinical stage biotechnology company developing best-in-class treatments for inflammatory and metabolic diseases, announced today the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for a Phase 1 clinical trial of ABP-745, an anti-inflammatory oral small molecule drug, for the treatment of acute gout.

Key Points: 
  • Atom Bioscience (Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd.), a clinical stage biotechnology company developing best-in-class treatments for inflammatory and metabolic diseases, announced today the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for a Phase 1 clinical trial of ABP-745, an anti-inflammatory oral small molecule drug, for the treatment of acute gout.
  • Atom also has submitted an IND application for a Phase 1 clinical of ABP-745 in China.
  • Dr. William Dongfang Shi, Founder, Chairman and CEO of Atom Biosciences, said, “The IND clearance of ABP-745 is important progress in the anti-inflammatory research field of Atom Bioscience’s clinical development.
  • We expect to begin the Phase 1 trial for acute gout in the U.S. soon.

Hyatt Regency Hakone Resort and Spa Enhances its Wellness Treatments at Spa IZUMI

Retrieved on: 
Wednesday, November 8, 2023

TOKYO, Nov 8, 2023 - (JCN Newswire) - Hyatt Regency Hakone Resort and Spa, surrounded by Hakone's natural beauty, is pleased to announce the launch of its renewed Spa IZUMI treatment menu, beginning on November 1, 2023.

Key Points: 
  • TOKYO, Nov 8, 2023 - (JCN Newswire) - Hyatt Regency Hakone Resort and Spa, surrounded by Hakone's natural beauty, is pleased to announce the launch of its renewed Spa IZUMI treatment menu, beginning on November 1, 2023.
  • One of the newly introduced treatments, "Onsen Leg Relief," is more than just a spa treatment and incorporates the therapeutic benefits of the Owakudani hot springs.
  • This unique experience allows guests to harness the healing properties of this sulfuric acid spring, known for its rich sodium components.
  • The energy contained in the organic fruit seeds awakens your dormant healing power within, enhancing the body's ability to repair damage and regenerate.

Thinking of a(nother) tattoo this summer? What you need to know about sunburn, sweating and fading

Retrieved on: 
Saturday, December 30, 2023

More of us have tattoos than ever before. About 25% of Australians are inked. A tattoo can be a large investment in time, money and pain. So how do you take care of your tattooed skin? Here’s what you need to know about sunburn, sweating and fading.

Key Points: 


More of us have tattoos than ever before. About 25% of Australians are inked. A tattoo can be a large investment in time, money and pain. So how do you take care of your tattooed skin? Here’s what you need to know about sunburn, sweating and fading.

Read more:
Tattoos have a long history going back to the ancient world – and also to colonialism

What’s a tattoo, dermatologically speaking?


Tattoo inks are deposited in the layer of skin called the dermis. This layer contains sweat and oil glands, a blood supply, immune cells, collagen to support the skin’s structures, and fibroblasts, which produce collagen.
Fibroblasts take up the ink particles, as do immune cells in the dermal tissue known as macrophages. The ink particles also stick inside bundles of collagen. Between these three mechanisms, the dermis holds tattoo inks so well they can be seen even on the 5,300-year-old ice mummy Ötzi.

Read more:
What Ötzi the prehistoric iceman can teach us about the use of tattoos in ceremonial healing or religious rites

Can I get a tattoo if I’m sunburnt?

  • During sunburn, your skin calls in extra immune cells and fluid to kill off and break down cells that have too much UV damage.
  • This inflammation can affect the tattoo ink deposits.

How soon after my new tattoo can I go into the sun?


There’s not much research on how soon you can expose your new tattoo to the sun. However, most tattooists advise you to avoid sun exposure while the tattoo heals, generally about three weeks. This seems sensible, as your fresh tattoo is a type of wound.

  • There is an influx of immune cells to deal with the damage, much like a sunburn.
  • So, in one way, you should treat your new tattoo like sunburn and avoid sun exposure while it heals.
  • But you shouldn’t use sunscreen on the tattoo in that time.

What happens if my tattoo gets sunburnt?

  • There’s usually swelling, itching or stinging on the tattoo site that can start immediately or develop over the course of a day.
  • There is also a small amount of evidence that sunburn on a tattoo temporarily suppresses the skin’s immune system, allowing an infection to become established.

Do tattoos increase my risk of skin cancer?

  • However, there’s no evidence skin cancers are more likely in tattooed skin.
  • Tattoos make newly-developed skin cancers more difficult to detect.
  • Red tattoos seem to be more prone to large but benign (non-cancerous) skin tumours called keratoacanthomas.
  • However, they can be difficult to distinguish from squamous cell carcinomas (a type of skin cancer).

Can sunlight fade my tattoo?

  • As tattoos age, they can fade a bit as some of the loose ink particles filter deeper into the dermis.
  • Sun exposure can also degrade ink particles.
  • After all, most people don’t want to fade their tattoos for science.

Does tattooed skin sweat differently to un-inked skin?

  • If you’ve got a full sleeve or your whole back is your canvas, that’s a significant amount of skin.
  • Since tattooing punctures the skin repeatedly, sweat glands in the dermis may be damaged.
  • However, when other researchers looked at sweating induced by exercise there was no effect in the volume of sweat between tattooed and un-tattooed skin.

Longer-term risks


When performed under the clean conditions of a licenced tattoo parlour, tattooing is relatively safe. But long term, some people develop allergic reactions to certain colours due to the different compounds in each, most commonly red dyes. This can cause lumps, scales, scarring or other visible changes. So, what’s the most common long-term side effect of tattoos? Tattoo regret and wanting to have them removed.
Katie Lee receives funding from the National Health and Medical Research Council. Erin McMeniman does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Stepping Into Winter: Watch Out for Common Foot and Ankle Injuries

Retrieved on: 
Thursday, December 21, 2023

Unfortunately, the accumulation of ice and snow can make sidewalks and roads slippery, which can lead to slips, falls and foot and ankle injuries.

Key Points: 
  • Unfortunately, the accumulation of ice and snow can make sidewalks and roads slippery, which can lead to slips, falls and foot and ankle injuries.
  • Watch out for common foot and ankle injuries and follow advice from foot and ankle orthopaedic surgeons to help you stay pain free this winter and enjoy the holidays with family and friends.
  • “The slick surfaces can cause rotational injuries to the foot and ankle,” he said.
  • Keeping your feet as dry as possible will help prevent athlete’s foot as well as cold-related foot injuries such as frostbite, he said.

Mario Gonzalez Wrongful Death Case Against Alameda Officers Settles for $11 Million

Retrieved on: 
Friday, December 15, 2023

The parties then negotiated this settlement, which was approved by the Alameda City Council and its insurers last night, December 14.

Key Points: 
  • The parties then negotiated this settlement, which was approved by the Alameda City Council and its insurers last night, December 14.
  • Officer McKinley asked Mario Gonzalez how he was doing, and Mr. Gonzalez responded that he was fine, although he appeared confused and disoriented.
  • Officers’ body-camera video shows officers placing Mr. Gonzalez in multiple pain compliance holds before they forced him face-down on the ground.
  • Officers forced Mr. Gonzalez into a prone position, and Officers McKinley and Fisher held him down with their force and body weight.