Lichen

• IRVINE, Calif., March 25, 2024 /PRNewswire/ -- LightBox announced today that its RCM capital markets technology platform is the engine powering Walker & Dunlop's recently launched W&D investor portal ( www.wdinvestorportal.com ).
• The portal is a customized and curated marketplace experience for buyers and sellers of commercial real estate and is a specially adapted configuration of LightBox RCM technology for the Walker & Dunlop broker and investor community.
• The W&D portal delivers an integrated source for marketing and managing Walker & Dunlop property listings to streamline transactions among deal participants.
• "This portal is part of our overall strategy to reach our 'Drive to 25' goals," said Walker Harris, senior vice president and director of operations, Walker & Dunlop Investment Sales.

• Most of them grow from southern Oregon down into northern California, snugged up against the rugged Pacific coast.
• Redwoods, like all trees, are engineered marvels.
• They even have two kinds of leaves that help the trees adapt to both wet and dry conditions.
• Researchers and horticulturists at the botanical gardens are thinking about trees, and how to integrate them into larger landscapes, in new ways.

Redwood communities

• A structure or building typically is a sort of island unto itself, separate from its neighbors; in contrast, the coast redwood is an ecosystem with enormously broad consequences for other life forms.
• Some of these life forms rely on the tree; others on occupants in and around the tree.
• The coast redwood hosts so many different ecological interactions that it’s faintly ridiculous.
• Nestled into extensive mats of ferns that grow high up in redwood canopies, researchers find aquatic crustaceans called copepods that normally would live in larger bodies of water.

Enduring but not static

• Even species as enduring as coast redwoods are affected by climate change.
• New fire dangers put them at risk, and more frequent floods erode the big trees’ footing.
• Since these trees are so networked and interconnected, the sum is greater than its parts and isn’t easy to quantify.

New territory

• I’ve resisted giving names to this duo, although many giant redwoods have monikers like Adventure, Brutus, Nugget, Paradox and Atlas – most named by the scientists who first quantified their extreme heights.
• The redwoods outside my window are perhaps 100 feet tall – puny by comparison to their northern brethren.

Daniel Lewis does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

• MC2-25 VLS is a novel treatment paradigm based on a di-peptide that inhibits carbamylation of amino acids and proteins in skin.
• MC2 Therapeutics believes that carbamylation of amino acids and proteins in the vulvar region by iso-cyanate is the root cause of VLS.
• The Phase 2 clinical trial is being conducted at multiple centres across Denmark and will evaluate the safety and efficacy of MC2-25 VLS in patients with VLS.
• The data generated from this double-blinded, placebo-controlled PoC trial will inform the trial design for a larger Phase 2b trial.

• The tree’s dramatic and photogenic setting made it a culturally significant landmark, often used as a symbol of the surrounding Northumberland region.
• However, this single tree also symbolised our relationship with the landscape in this part of the world, both past and future.
• Sycamores are also often found in soil with lots of different fungal species, and they’re an important habitat for lichens.

300 years of change

• The sycamore needed this tough coloniser biology to survive its 300 year or so lifespan in Northumberland, where it endured significant environmental changes over the centuries.
• Those summers became drier and brighter in the 20th century, until anthropogenic climate change really took hold and the tree recently withstood its hottest decade on record.
• The landscape of Northumberland is also not fixed, but has seen significant alterations often driven by thousands of years of human economic and social change.
• Don’t have time to read about climate change as much as you’d like?