Social cognition

High Prevalence of Cognitive Impairment in Patients with Heart Failure Shown to Negatively Impact Disease Self-Management

Retrieved on: 
Tuesday, March 12, 2024
Function (mathematics), JCF, Prevalence, Learning, Deficit spending, Disease, Cognitive deficit, Heart failure, Memory, Patient, University of Utah, Knowledge, Journal, University, HF, Life expectancy, Science, Heart, MPH, Social cognition, Diuretic, Language, Medical device

The Cognitive Impairment in Heart Failure: A Heart Failure Society of America Scientific Statement published today in the Journal of Cardiac Failure (JCF), indicates that clinicians have a responsibility to recognize and address cognitive impairment as an integral component of personalized care for patients with heart failure (HF).

Key Points: 
  • The Cognitive Impairment in Heart Failure: A Heart Failure Society of America Scientific Statement published today in the Journal of Cardiac Failure (JCF), indicates that clinicians have a responsibility to recognize and address cognitive impairment as an integral component of personalized care for patients with heart failure (HF).
  • Heart failure clinicians should be equipped with tools to assess and identify markers for cognitive impairment.
  • Cognitive Impairment in Heart Failure outlines several domains affected by cognitive impairment including learning and memory, executive function, complex attention, perceptual-motor function, language, and social cognition.
  • The Cognitive Impairment in Heart Failure: A Heart Failure Society of America Scientific Statement is available online in the JCF at www.onlinejcf.com .

CuraSen Therapeutics Announces Oral Presentation of Additional Positive Phase 2a Data with CST-2032/CST-107 in Patients with Alzheimer’s or Parkinson’s Disease at AD/PD™ 2024 International Conference

Retrieved on: 
Thursday, March 7, 2024
Science, Neurology, Biotechnology, Research, Pharmaceutical, Health, Mental Health, Clinical Trials, Facial expression, PD, Doctor of Philosophy, Computation, CST, Cognition, Neurodegenerative disease, Conference, Nadolol, Safety, Attention, Social cognition, Biomarker, Therapy, Memory, Dementia, Facial recognition, Function (mathematics), MCI, Tablet, DSM-IV codes, DNA, Brain, Pharmaceutical industry

The oral presentation will take place at AD/PD™ 2024: The International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders, being held March 5-9, 2024, in Lisbon, Portugal.

Key Points: 
  • The oral presentation will take place at AD/PD™ 2024: The International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders, being held March 5-9, 2024, in Lisbon, Portugal.
  • CST-2032 is one of CuraSen’s two lead product candidates being tested in patients with Alzheimer’s and Parkinson’s disease.
  • Both CST-2032 and CST-103 work by enabling reactivation of brain adrenergic function lost early in the neurodegenerative disease process.
  • Target effect sizes of 0.2-0.3 or higher, as seen in this study, predict success in larger, longer studies.

How having five friends boosts the adolescent brain – and educational performance

Retrieved on: 
Wednesday, July 19, 2023
Cognition, Human, Friends, Vocabulary, Parent, Brain, Emotion, Attention, COVID, Research, Language, Social cognition, ABCD, Achievement Medal, Data, Reading, Adolescence, Ageing, Mental health, Social Problems, Memory, Toy, Design, Mobile phone, Tutoring, Ofsted

And in our latest study, published in eLife, we show that having roughly five friends during the beginning of adolescence is beneficial for cognition, mental health and educational performance.

Key Points: 
  • And in our latest study, published in eLife, we show that having roughly five friends during the beginning of adolescence is beneficial for cognition, mental health and educational performance.
  • In terms of brain health, we found that the number of close friends was related to the area and volume of the cortex (the outermost layer of the brain).
  • Having five friends was linked to having more volume in these cortical regions.
  • This is the best way to promote social cognition, which will in turn boost educational attainment and wellbeing.

Tonix Pharmaceuticals Announces Agreement and Initiation of Enrollment in Phase 2 Trial with the University of Washington to Study TNX-1900 (Potentiated Intranasal Oxytocin) for Social Anxiety Disorder

Retrieved on: 
Monday, July 17, 2023
Tonix Pharmaceuticals, Human, Central nervous system, University, DSM-IV codes, Magnesium, Anxiety, University of Washington, Fear, SAD, University of Bath Department of Psychology, Research, Social cognition, Oxytocin, Assistant professor, Acquisition, Animal, University of Washington School of Social Work, Social anxiety disorder, Behavior, Safety, Nursing, Pharmaceutical industry

Tonix entered into an agreement with the University of Washington to examine the potential role of TNX-1900 with Angela Fang, Ph.D., Assistant Professor, Department of Psychology, University of Washington as the principal investigator.

Key Points: 
  • Tonix entered into an agreement with the University of Washington to examine the potential role of TNX-1900 with Angela Fang, Ph.D., Assistant Professor, Department of Psychology, University of Washington as the principal investigator.
  • “We are excited to collaborate with the University of Washington and Dr. Fang on the development of TNX-1900 for social anxiety disorder,” said Seth Lederman, M.D., Chief Executive Officer of Tonix Pharmaceuticals.
  • These studies have shown that intranasal oxytocin may hold therapeutic promise for psychiatric disorders involving social deficits3-5.
  • The primary objective of the Phase 2 study is to examine the potential role of TNX-1900 in enhancing vicarious extinction learning in SAD, compared to healthy controls.

New Study: Brain Training Reduces Aggressive Behavior in People with Schizophrenia

Retrieved on: 
Tuesday, June 20, 2023
Cognition, Psychiatry, Exercise, Violence, Manhattan Psychiatric Center, Quality of life, Aggression, Research, Attention, History, Social cognition, Medicare, Patient, Risk, SAN, Hearing, Posit Science Corporation, Spectrum, Grammatical mood, Remedy, Social, Memory, Passive-aggressive behavior, Pharmaceutical industry, Schizophrenia

This study used the brain training app, BrainHQ from Posit Science .

Key Points: 
  • This study used the brain training app, BrainHQ from Posit Science .
  • While antipsychotic drugs are routinely used to manage aggression in schizophrenia, their benefits are limited by issues of non-adherence and inadequate treatment response.
  • A number of prior studies in schizophrenia found that BrainHQ exercises improved measures of cognitive function and social cognition in people with Schizophrenia.
  • The researchers hypothesized that a combination of BrainHQ exercises with computerized social cognition exercises might reduce aggressive behavior more than BrainHQ alone.

Drinking During Pregnancy Changes Baby's Brain Structure

Retrieved on: 
Tuesday, November 22, 2022
Health, Penning trap, Perception, Learning, Behavioral Problems, Medical imaging, STS, Society, Cerebral cortex, Pregnancy, Doctor of Philosophy, Medical school, Fetus, Korea Disease Control and Prevention Agency, Mother, Skull, Radiology, Neuroradiology, RSNA, Education, Research, Medical University of Vienna, Division, Radiological Society of North America, Social cognition, Alcohol abuse, Radiation, MRI, Brain, Speech, Language

CHICAGO, Nov. 22, 2022 /PRNewswire/ -- A new MRI study revealed that consumption of alcohol even in low to moderate amounts during pregnancy can change the baby's brain structure and delay brain development.

Key Points: 
  • CHICAGO, Nov. 22, 2022 /PRNewswire/ -- A new MRI study revealed that consumption of alcohol even in low to moderate amounts during pregnancy can change the baby's brain structure and delay brain development.
  • "We found the greatest changes in the temporal brain region and STS," Dr. Kasprian said.
  • Six mothers also reported at least one binge drinking event (exceeding four drinks on one occasion) during pregnancy.
  • "As we show in our study, even low levels of alcohol consumption can lead to structural changes in brain development and delayed brain maturation."

BrainHQ and Highmark Wholecare Target Fall Risk Reduction in Pennsylvania's Vulnerable Elderly Population

Retrieved on: 
Monday, August 15, 2022
Risk, Posit Science Corporation, CEO, Medicare, IOS, GLOBE, Population, Technology, Brain, Cognition, Falls, Hospital, Memory, Library, Attention, Health, Quality of life, SAN, Medicaid, Program, Even and odd functions, Gait, Android, Physician, Capital punishment, Social cognition, Medicine, Mobile phone, Health insurance

BrainHQs brain fitness exercises and services were recently made available to approximately 7,000 eligible Highmark Wholecare dual eligible Medicaid/Medicare members who were identified as a high risk for falls.

Key Points: 
  • BrainHQs brain fitness exercises and services were recently made available to approximately 7,000 eligible Highmark Wholecare dual eligible Medicaid/Medicare members who were identified as a high risk for falls.
  • BrainHQ exercises have been shown in multiple studies to improve mobility and decrease fall risk.
  • At Highmark Wholecare, our mission is to care for the whole person and bring services to individuals in the communities in which they live, saidBeth Dimpfl, Manager, Strategy and Execution, Highmark Wholecare.
  • We are proud to launch this innovative demonstration project with BrainHQ to address fall risk, and to provide eligible members with the many other benefits of BrainHQ.

Brain & Behavior Research Foundation Honors Outstanding Psychiatric Researchers

Retrieved on: 
Monday, August 1, 2022
Lists of diseases, MRI, Neuron, Brain, Psychiatry, Gerald Klerman, GLOBE, Physician, TMS, Human, Foundation, Schizophrenia, CEO, Neuropsychiatry, Brain & Behavior Research Foundation, Research, Deep brain stimulation, Transcranial magnetic stimulation, Psychosis, Institute, Emotional and behavioral disorders, Psychopathology, Even and odd functions, Diffusion, Language, Executive dysfunction, Behavior, DBS, Technology, Method, Medical research, Washington University School of Medicine, Social cognition, George Washington University School of Engineering and Applied Science, Population, Cognitive neuroscience, Pharmaceutical industry, Medical device, Medical imaging

The Klerman and Freedman prizes recognize innovative thinking and outstanding talent across the field of neuropsychiatry, said Jeffrey Borenstein, M.D., President and CEO of the Brain & Behavior Research Foundation.

Key Points: 
  • The Klerman and Freedman prizes recognize innovative thinking and outstanding talent across the field of neuropsychiatry, said Jeffrey Borenstein, M.D., President and CEO of the Brain & Behavior Research Foundation.
  • We applaud these researchers for their groundbreaking work, and we thank our generous donors for supporting scientists in brain and behavior research.
  • Six scientists received recognition for their outstanding work in brain and behavior research:
    Dr. Siddiqis research is focused on causal mapping of human brain function and dysfunction.
  • Using techniques such as functional connectivity MRI, Dr. Siddiqi maps brain circuits to link brain lesions and brain stimulation sites that can modify different psychiatric symptoms.

Study Suggests Cognitive Decline and Dementia May Be Preventable and Reversible

Retrieved on: 
Thursday, July 7, 2022
Memory, Patient, CEO, Dementia, Journal, Social cognition, Even and odd functions, Attention, GLOBE, Element, Gait, Moca, SAN, Publication, Risk, Worldwide, Library, MCI, Quality of life, Cognition, Incidence, Medicare, Posit Science Corporation, Randomized controlled trial, Medical imaging, Toy

For the cognitive training portion of the treatment, the study used computerized brain exercises from the BrainHQ app, made by Posit Science .

Key Points: 
  • For the cognitive training portion of the treatment, the study used computerized brain exercises from the BrainHQ app, made by Posit Science .
  • This single-arm, proof-of-concept, study enrolled twenty-five patients with dementia or Mild Cognitive Impairment (MCI) a pre-dementia condition that denotes high risk for dementia.
  • At baseline, each patient was evaluated for numerous markers associated with cognitive decline.
  • This study builds on the 20 prior publications on BrainHQ in pre-dementia conditions and the two prior dementia prevention studies (showing reductions in dementia risk and/or incidence).

YMCA of San Francisco and BrainHQ Implementing NIH-funded Dementia Prevention Program

Retrieved on: 
Monday, June 27, 2022
Memory, Government, YMCA, CEO, DPP, Dementia, Social cognition, Even and odd functions, Attention, American Academy, World Health Organization, National Institute, Gait, Curriculum, NIH, World, Woman, University of California, San Francisco, Risk, American Academy of Neurology, Library, Diabetes, Diet, University, YMCA Hotel (San Francisco, California), Lou Ruvo Center for Brain Health, Organization, Â, Quality of life, Medicare, Program, Posit Science Corporation, Cognition, Pharmaceutical industry, Mobile phone, Neurology

The community-based Brain Health Program plans to leverage the behavioral change infrastructure developed by the Diabetes Prevention Program (DPP).

Key Points: 
  • The community-based Brain Health Program plans to leverage the behavioral change infrastructure developed by the Diabetes Prevention Program (DPP).
  • The Brain Health Program is being developed by Posit Science and the YMCA in collaboration with brain health experts at the University of California, San Francisco.
  • The Diabetes Prevention Program reduced new cases of diabetes by more than 50%, and I believe the Brain Health Program should have a similar effect on dementia.
  • The YMCA of San Francisco strives to address community needs and fill programming-based gaps in order to provide the greatest impact in San Francisco, Marin, and San Mateo counties through 14 YMCA campuses and 160 off-campus programs.