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Birth control PHILADELPHIA, June 5, 2023 /PRNewswire/ -- Yesterday, more than 3,000 people gathered at the Philadelphia Zoo to celebrate the 27th Children's Hospital of Philadelphia (CHOP) Fetal Family Reunion, representing patients and families from across the country.
Key Points:
- PHILADELPHIA, June 5, 2023 /PRNewswire/ -- Yesterday, more than 3,000 people gathered at the Philadelphia Zoo to celebrate the 27th Children's Hospital of Philadelphia (CHOP) Fetal Family Reunion, representing patients and families from across the country.
- The reunion brings together a unique community of families who have shared similar experiences.
- Babies diagnosed before birth either underwent fetal surgery to treat the condition in utero or received highly complex care immediately after birth.
- The team has also managed thousands of pregnancies complicated by birth defects in which newborns need immediate specialized medical care or surgery after delivery.
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MD Morgan Properties donation will help further the CVP’s outstanding work in the prevention of violence through evidence-based interventions.
Key Points:
- Morgan Properties donation will help further the CVP’s outstanding work in the prevention of violence through evidence-based interventions.
- A key aim of the Center for Violence Prevention is to reduce early exposure to violence whenever possible and to utilize appropriate interventions to mitigate the impact of violence when a child is victimized.
- The Center’s research and programs focus on important areas like bullying prevention, community violence and trauma support, suicide prevention and gun safety.
- “Morgan Properties looks forward to sponsoring CHOP’s CVP to help fund their research and programs, and to providing access to their educational resources and prevention tools to the thousands of people who call our communities home,” added Jonathan Morgan, President of Morgan Properties JV.
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Toy PHILADELPHIA, May 24, 2023 /PRNewswire/ -- Repeatedly heading a soccer ball has been previously associated with negative long-term brain health for professional players. However, in a new study from researchers at the Minds Matter Concussion Program at Children's Hospital of Philadelphia (CHOP), a small number of repeated soccer headers equivalent to a throw-in did not cause immediate neurophysiological deficits for teens, suggesting that limited soccer heading exposure in youth sports may not result in irreversible harm if players are properly trained.
Key Points:
- The findings, which represent the most comprehensive real-time study of soccer headers in adolescent athletes, were published in the Journal of Biomechanical Engineering .
- For some professional athletes, repeated head loading in sports – using your head as part of the game – is associated with negative long-term brain health even when there are no initial clinical symptoms.
- Despite the awareness of long-term consequences, short-term neurophysiological issues after repeated head impacts like soccer heading are poorly understood in youth athletes.
- The study did not assess the safety of regular soccer headers over the course of a season or scholastic career.
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MD PHILADELPHIA, May 18, 2023 /PRNewswire/ -- Children's Hospital of Philadelphia (CHOP) announced that it has received a multi-million dollar gift from the Topolewski family, longstanding supporters of the Cardiac Center at CHOP , to establish the Topolewski Pediatric Heart Valve Center .
Key Points:
- PHILADELPHIA, May 18, 2023 /PRNewswire/ -- Children's Hospital of Philadelphia (CHOP) announced that it has received a multi-million dollar gift from the Topolewski family, longstanding supporters of the Cardiac Center at CHOP , to establish the Topolewski Pediatric Heart Valve Center .
- The Topolewski Pediatric Heart Valve Center brings together a comprehensive team of cardiac surgeons, cardiologists, scientists, researchers, and experts in interventional cardiology and cardiac imaging to revolutionize pediatric cardiac care.
- This multidisciplinary group takes a coordinated approach and is working to develop precise, evidence-based long-term solutions for infants and children with heart valve disease.
- As part of the Topolewski family gift, Dr. Jolley will hold the inaugural Topolewski Endowed Chair in Pediatric Cardiology.
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Immunology PHILADELPHIA, May 17, 2023 /PRNewswire/ -- Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called "Isoform peptides from RNA splicing for Immunotherapy target Screening" (IRIS), was described in a paper published today in the Proceedings of the National Academy of Sciences.
Key Points:
- "We know that aberrant alternative RNA splicing is widespread in cancer and generates a range of potential immunotherapy targets.
- In our study, we were able to show that our computational platform was able to identify immunotherapy targets that arise from alternative splicing, introducing a broadly applicable framework for discovering novel cancer immunotherapy targets that arise from this process."
- "This proof-of-concept study demonstrates that alternatively spliced RNA transcripts are viable targets for cancer immunotherapy and provides a big data and multiomics-powered computational platform for finding these targets," Dr. Xing added.
- "IRIS: discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing," Proceedings of the National Academy of Sciences, online May 16, 2023, DOI: 10.1073/pnas.2221116120
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Urology PHILADELPHIA, May 2, 2023 /PRNewswire/ -- Children's Hospital of Philadelphia (CHOP) has named Thomas F. Kolon, MD, as Chief of the Division of Urology. Dr. Kolon has served as the Associate Chief of CHOP's Division of Urology since 2014 and is a Professor of Urology at the Perelman School of Medicine at the University of Pennsylvania. He is an expert in the care of children with genital disorders and renal, bladder, and prostate cancer and has helped develop creative 3-D printing models for planning safe organ-sparing surgery. A talented and accomplished researcher and physician, Dr. Kolon holds the Howard M. Snyder III Endowed Chair in Pediatric Urology at CHOP.
Key Points:
- PHILADELPHIA, May 2, 2023 /PRNewswire/ -- Children's Hospital of Philadelphia (CHOP) has named Thomas F. Kolon, MD, as Chief of the Division of Urology.
- Dr. Kolon has served as the Associate Chief of CHOP's Division of Urology since 2014 and is a Professor of Urology at the Perelman School of Medicine at the University of Pennsylvania.
- Following his pediatric urology fellowship at Texas Children's Hospital, he served as Director of Pediatric Urology at the Naval Medical Center-San Diego.
- Dr. Kolon is currently the executive secretary for the Pediatric Urology Advisory Council to the American Board of Urology.
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Nursing PHILADELPHIA, April 19, 2023 /PRNewswire/ -- Children's Hospital of Philadelphia (CHOP) today announced a $6.15 million donation from The Wawa Foundation to elevate and expand the hospital's Wawa Volunteer Services program. The gift will establish a Wawa Coffee and Care Cart, currently operating on CHOP's Philadelphia campus, at CHOP's second inpatient hospital, the Middleman Family Pavilion in King of Prussia, in July 2023. The gift will also enable the purchase and upgrade of coffee makers, single serve brewing systems, pods and other accessories to provide a warm drink to employees, patient families and visitors. Additionally, the gift will provide funding for the reception area of a Family Resource Center in the new patient tower on CHOP's Philadelphia campus, scheduled to open in 2028.
Key Points:
- To recognize this investment, the welcome area of the Family Resource Center will incorporate The Wawa Foundation's name.
- While Wawa Volunteer Services at CHOP was established in 2016, Wawa's legacy of support for CHOP began more than 165 years ago.
- Since 1855, Wawa and CHOP have shared a steadfast commitment to compassionate care for children and an emphasis on serving the entire family.
- "The Wawa Foundation's investment will empower us to deliver a seamless, inclusive, family-centered experience to everyone who enters our doors.
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Woman Throughout her distinguished career, Dr. Furth has had a passion for mentoring junior researchers, personally mentoring many students, residents, postdoctoral fellows and junior faculty.
Key Points:
- Throughout her distinguished career, Dr. Furth has had a passion for mentoring junior researchers, personally mentoring many students, residents, postdoctoral fellows and junior faculty.
- "It's incredibly meaningful to be recognized with this award from ACTS," Dr. Furth said.
- ACTS presents its annual Translational Science Awards to recognize investigators for their outstanding contributions to the clinical research and translational science field.
- The ACTS Distinguished Educator: Mentorship Innovation Award recognizes distinguished mentors with outstanding innovation in mentorship resulting in significant scientific accomplishments by the next generation of clinical and translational researchers and/or innovative approaches in mentorship to promote diversity and retention of under-represented groups in translational research.
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Child While prior studies provided strong evidence for the benefits of early intervention in autism, many are correlation studies rather than randomized controlled studies that can provide more conclusive results.
Key Points:
- While prior studies provided strong evidence for the benefits of early intervention in autism, many are correlation studies rather than randomized controlled studies that can provide more conclusive results.
- Researchers used the Early Social Interaction (ESI) model, a parent-implemented intervention for toddlers diagnosed with autism that provides a framework to support a child's development in social communication and active engagement.
- The study found that children who received individualized ESI coaching earlier showed greater gains in use and understanding of language, social use of communication skills, and self-help skills.
- This research was also supported in part by the funding from Autism Speaks and the Simons Foundation.
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Nature PHILADELPHIA, April 5, 2023 /PRNewswire/ -- In a twist on the question, "Which came first, the chicken or the egg?", scientists have long faced a similar question about how human adenovirus replicates: "Which comes first, assembly of the viral particle, or packaging of the viral genome?" Now, in a new study published today in Nature, researchers at Children's Hospital of Philadelphia (CHOP) have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.
Key Points:
- However, little is known about how genome replication, particle assembly, and genome packaging are coordinated in the crowded nuclear environment.
- Led by Dr. Charman, we have shown that a biophysical process known as phase separation allows this process to occur in an orderly, coordinated fashion."
- To investigate the potential role of BMCs in this process, the researchers studied adenovirus, a nuclear-replicating DNA virus.
- Because the adenovirus proteins involved in genome replication are distinct from those involved in particle assembly and genome packaging, the researchers reasoned focusing on this virus would allow them to dissect and more easily identify the role of phase separation in specific viral processes.
